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SCFBio, IIT Delhi Hauz Khas, New Delhi

Molecular Targets

Interactions between compounds and specific gene/protein targets.

Total Rows 750,454
Pages 30,019
BIMP_ID Target Name Gene Organism Action Source URL
Abcb1a
Rattus norvegicus (Norway rat)
Amphetamine results in decreased expression of ABCB1A mRNA
https://ctdbase.org/detail.go?type=gene&acc=18671
Abcb1a
Mus musculus (house mouse)
ABCB1A gene mutant form results in decreased susceptibility to diclofenac
https://ctdbase.org/detail.go?type=gene&acc=18671
Abcb1a
Mus musculus (house mouse)
Diclofenac results in decreased activity of ABCB1A protein
https://ctdbase.org/detail.go?type=gene&acc=18671
Abcb1a
Cricetulus griseus (Chinese hamster)
Mitotane inhibits the reaction [ABCB1A protein results in decreased susceptibility to daunorubicin]|abcb1a protein results in decreased susceptibility to daunorubicin
https://ctdbase.org/detail.go?type=gene&acc=18671
Abcb1a
Homo sapiens (human)
Cyclosporine inhibits the reaction [ABCB1A protein results in increased export of daunorubicin]|abcb1a protein results in increased export of daunorubicin
https://ctdbase.org/detail.go?type=gene&acc=18671
Abcb1a
Mus musculus (house mouse)
ABCB1A affects the susceptibility to daunorubicin
https://ctdbase.org/detail.go?type=gene&acc=18671
Abcb1a
Mus musculus (house mouse)
Pirinixic acid results in increased expression of ABCB1A mRNA
https://ctdbase.org/detail.go?type=gene&acc=18671
Abcb1a
Rattus norvegicus (Norway rat)
Pirinixic acid affects the expression of ABCB1A mRNA
https://ctdbase.org/detail.go?type=gene&acc=18671
Abcb1a
Mus musculus (house mouse)
Mifepristone results in increased expression of ABCB1A mRNA
https://ctdbase.org/detail.go?type=gene&acc=18671
Abcb1a
Rattus norvegicus (Norway rat)
Ascorbic acid inhibits the reaction [abamectin results in increased expression of ABCB1A mrna]|[ascorbic acid co-treated with sesame oil] inhibits the reaction [abamectin results in increased expression of ABCB1A mrna]
https://ctdbase.org/detail.go?type=gene&acc=18671
Abcb1a
Rattus norvegicus (Norway rat)
[rifampin metabolite results in decreased activity of ABCB1A protein] which results in decreased abundance of adenosine triphosphate
https://ctdbase.org/detail.go?type=gene&acc=18671
Abcb1a
Mus musculus (house mouse)
[dietary fats co-treated with dietary sucrose] results in increased expression of ABCB1A mRNA
https://ctdbase.org/detail.go?type=gene&acc=18671
Abcb1a
Mus musculus (house mouse)
Reserpine inhibits the reaction [ABCB1A protein results in increased secretion of fluorexon]
https://ctdbase.org/detail.go?type=gene&acc=18671
Abcb1a
Rattus norvegicus (Norway rat)
Piperonyl butoxide results in increased expression of ABCB1A mRNA
https://ctdbase.org/detail.go?type=gene&acc=18671
Abcb1a
Rattus norvegicus (Norway rat)
T-2 toxin results in decreased expression of ABCB1A mRNA
https://ctdbase.org/detail.go?type=gene&acc=18671
Abcb1a
Rattus norvegicus (Norway rat)
[morphine co-treated with naloxone] results in increased expression of ABCB1A mRNA
https://ctdbase.org/detail.go?type=gene&acc=18671
Abcb1a
Rattus norvegicus (Norway rat)
[sulforaphane co-treated with aflatoxin B1] affects the expression of ABCB1A mRNA
https://ctdbase.org/detail.go?type=gene&acc=18671
Abcb1a
Rattus norvegicus (Norway rat)
Sulforaphane inhibits the reaction [genistein results in increased expression of ABCB1A mrna]
https://ctdbase.org/detail.go?type=gene&acc=18671
Abcb1a
Rattus norvegicus (Norway rat)
Oxycodone results in increased expression of ABCB1A protein|oxycodone results in increased expression of ABCB1A mRNA
https://ctdbase.org/detail.go?type=gene&acc=18671
Abcb1a
Homo sapiens (human)
ABCB1A protein results in increased transport of cyclosporine
https://ctdbase.org/detail.go?type=gene&acc=18671
Abcb1a
Homo sapiens (human)
Cyclosporine inhibits the reaction [ABCB1A protein results in increased export of technetium tc 99m sestamibi]|cyclosporine inhibits the reaction [ABCB1A protein results in increased export of daunorubicin]
https://ctdbase.org/detail.go?type=gene&acc=18671
Abcb1a
Mus musculus (house mouse)
ABCB1A protein affects the susceptibility to [pentobarbital co-treated with cyclosporine]
https://ctdbase.org/detail.go?type=gene&acc=18671
Abcb1a
Mus musculus (house mouse)
Cyclosporine results in decreased activity of ABCB1A protein|abcb1a protein results in increased export of cyclosporine
https://ctdbase.org/detail.go?type=gene&acc=18671
Abcb1a
Mus musculus (house mouse)
Cyclosporine inhibits the reaction [ABCB1A protein results in increased secretion of fluorexon]
https://ctdbase.org/detail.go?type=gene&acc=18671
Abcb1a
Mus musculus (house mouse)
Cyclosporine results in increased expression of ABCB1A mRNA
https://ctdbase.org/detail.go?type=gene&acc=18671
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