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Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
Abcb1a
|
Rattus norvegicus (Norway rat)
|
Amphetamine results in decreased expression of ABCB1A mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Mus musculus (house mouse)
|
ABCB1A gene mutant form results in decreased susceptibility to diclofenac
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Mus musculus (house mouse)
|
Diclofenac results in decreased activity of ABCB1A protein
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Cricetulus griseus (Chinese hamster)
|
Mitotane inhibits the reaction [ABCB1A protein results in decreased susceptibility to daunorubicin]|abcb1a protein results in decreased susceptibility to daunorubicin
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Homo sapiens (human)
|
Cyclosporine inhibits the reaction [ABCB1A protein results in increased export of daunorubicin]|abcb1a protein results in increased export of daunorubicin
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Mus musculus (house mouse)
|
ABCB1A affects the susceptibility to daunorubicin
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Mus musculus (house mouse)
|
Pirinixic acid results in increased expression of ABCB1A mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Rattus norvegicus (Norway rat)
|
Pirinixic acid affects the expression of ABCB1A mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Mus musculus (house mouse)
|
Mifepristone results in increased expression of ABCB1A mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Rattus norvegicus (Norway rat)
|
Ascorbic acid inhibits the reaction [abamectin results in increased expression of ABCB1A mrna]|[ascorbic acid co-treated with sesame oil] inhibits the reaction [abamectin results in increased expression of ABCB1A mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Rattus norvegicus (Norway rat)
|
[rifampin metabolite results in decreased activity of ABCB1A protein] which results in decreased abundance of adenosine triphosphate
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Mus musculus (house mouse)
|
[dietary fats co-treated with dietary sucrose] results in increased expression of ABCB1A mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Mus musculus (house mouse)
|
Reserpine inhibits the reaction [ABCB1A protein results in increased secretion of fluorexon]
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Rattus norvegicus (Norway rat)
|
Piperonyl butoxide results in increased expression of ABCB1A mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Rattus norvegicus (Norway rat)
|
T-2 toxin results in decreased expression of ABCB1A mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Rattus norvegicus (Norway rat)
|
[morphine co-treated with naloxone] results in increased expression of ABCB1A mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Rattus norvegicus (Norway rat)
|
[sulforaphane co-treated with aflatoxin B1] affects the expression of ABCB1A mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Rattus norvegicus (Norway rat)
|
Sulforaphane inhibits the reaction [genistein results in increased expression of ABCB1A mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Rattus norvegicus (Norway rat)
|
Oxycodone results in increased expression of ABCB1A protein|oxycodone results in increased expression of ABCB1A mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Homo sapiens (human)
|
ABCB1A protein results in increased transport of cyclosporine
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Homo sapiens (human)
|
Cyclosporine inhibits the reaction [ABCB1A protein results in increased export of technetium tc 99m sestamibi]|cyclosporine inhibits the reaction [ABCB1A protein results in increased export of daunorubicin]
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Mus musculus (house mouse)
|
ABCB1A protein affects the susceptibility to [pentobarbital co-treated with cyclosporine]
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Mus musculus (house mouse)
|
Cyclosporine results in decreased activity of ABCB1A protein|abcb1a protein results in increased export of cyclosporine
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Mus musculus (house mouse)
|
Cyclosporine inhibits the reaction [ABCB1A protein results in increased secretion of fluorexon]
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Mus musculus (house mouse)
|
Cyclosporine results in increased expression of ABCB1A mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
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