Molecular Targets : Dataset Browser

BIMP_ID	Target Name	Gene	Organism	Action	Source URL
BIMP082880	ABCB1A	Abcb1a	Rattus norvegicus (Norway rat)	Cyclosporine inhibits the reaction [ABCB1A protein results in increased export of risperidone]\|cyclosporine results in decreased activity of ABCB1A protein\|cyclosporine inhibits the reaction [ABCB1A protein results in increased export of paliperidone palmitate]	https://ctdbase.org/detail.go?type=gene&acc=18671
BIMP082958	ABCB1A	Abcb1a	Rattus norvegicus (Norway rat)	[morphine co-treated with naloxone] results in increased expression of ABCB1A mRNA	https://ctdbase.org/detail.go?type=gene&acc=18671
BIMP087829	ABCB1A	Abcb1a	Cricetulus griseus (Chinese hamster)	ABCB1A protein results in decreased susceptibility to vincristine	https://ctdbase.org/detail.go?type=gene&acc=18671
BIMP087829	ABCB1A	Abcb1a	Rattus norvegicus (Norway rat)	Vincristine results in increased expression of ABCB1A mRNA	https://ctdbase.org/detail.go?type=gene&acc=18671
BIMP079668	ABCB1A	Abcb1a	Rattus norvegicus (Norway rat)	Benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [isoborneol results in decreased expression of ABCB1A protein]	https://ctdbase.org/detail.go?type=gene&acc=18671
BIMP090429	ABCB1A	Abcb1a	Rattus norvegicus (Norway rat)	Dexamethasone inhibits the reaction [lipopolysaccharides results in decreased expression of ABCB1A mrna]	https://ctdbase.org/detail.go?type=gene&acc=18671
BIMP090429	ABCB1A	Abcb1a	Rattus norvegicus (Norway rat)	Dexamethasone results in decreased expression of ABCB1A mRNA	https://ctdbase.org/detail.go?type=gene&acc=18671
BIMP090429	ABCB1A	Abcb1a	Rattus norvegicus (Norway rat)	Dexamethasone results in increased expression of ABCB1A protein\|dexamethasone results in increased expression of ABCB1A mRNA	https://ctdbase.org/detail.go?type=gene&acc=18671
BIMP090535	ABCB1A	Abcb1a	Mus musculus (house mouse)	Estradiol results in decreased expression of ABCB1A mRNA	https://ctdbase.org/detail.go?type=gene&acc=18671
BIMP090535	ABCB1A	Abcb1a	Rattus norvegicus (Norway rat)	Estradiol results in decreased expression of ABCB1A mRNA	https://ctdbase.org/detail.go?type=gene&acc=18671
BIMP082232	ABCB1A	Abcb1a	Mus musculus (house mouse)	[vancomycin co-treated with neomycin co-treated with ampicillin co-treated with metronidazole co-treated with amphotericin B] results in increased expression of ABCB1A mRNA	https://ctdbase.org/detail.go?type=gene&acc=18671
BIMP082231	ABCB1A	Abcb1a	Rattus norvegicus (Norway rat)	Genistein results in increased expression of ABCB1A mrna\|sulforaphane inhibits the reaction [genistein results in increased expression of ABCB1A mrna]\|ketoconazole inhibits the reaction [genistein results in increased expression of ABCB1A mrna]\|nr1i2 protein affects the reaction [genistein results in increased expression of ABCB1A mrna]	https://ctdbase.org/detail.go?type=gene&acc=18671
BIMP082446	ABCB1A	Abcb1a	Rattus norvegicus (Norway rat)	Fulvestrant inhibits the reaction [zearalenone results in increased expression of ABCB1A mrna]	https://ctdbase.org/detail.go?type=gene&acc=18671
BIMP082446	ABCB1A	Abcb1a	Rattus norvegicus (Norway rat)	Zearalenone affects the expression of ABCB1A protein	https://ctdbase.org/detail.go?type=gene&acc=18671
BIMP082446	ABCB1A	Abcb1a	Rattus norvegicus (Norway rat)	Zearalenone results in decreased expression of ABCB1A mRNA	https://ctdbase.org/detail.go?type=gene&acc=18671
BIMP082446	ABCB1A	Abcb1a	Rattus norvegicus (Norway rat)	Zearalenone results in increased expression of ABCB1A mRNA	https://ctdbase.org/detail.go?type=gene&acc=18671
BIMP091061	ABCB1A	Abcb1a	Mus musculus (house mouse)	Ethinyl estradiol affects the expression of ABCB1A mRNA	https://ctdbase.org/detail.go?type=gene&acc=18671
BIMP091061	ABCB1A	Abcb1a	Mus musculus (house mouse)	[tetrachlorodibenzodioxin co-treated with ethinyl estradiol] results in decreased expression of ABCB1A mrna\|ethinyl estradiol results in decreased expression of ABCB1A mRNA	https://ctdbase.org/detail.go?type=gene&acc=18671
BIMP091061	ABCB1A	Abcb1a	Rattus norvegicus (Norway rat)	Ethinyl estradiol results in decreased expression of ABCB1A mRNA	https://ctdbase.org/detail.go?type=gene&acc=18671
BIMP091300	ABCB1A	Abcb1a	Mus musculus (house mouse)	ABCB1A gene mutant form results in decreased susceptibility to irinotecan	https://ctdbase.org/detail.go?type=gene&acc=18671
BIMP091300	ABCB1A	Abcb1a	Mus musculus (house mouse)	Everolimus inhibits the reaction [ABCB1A protein affects the metabolism of irinotecan]\|bis(4-nitrophenyl)phosphate inhibits the reaction [ABCB1A protein affects the metabolism of irinotecan]\|abcb1a protein affects the metabolism of irinotecan	https://ctdbase.org/detail.go?type=gene&acc=18671
BIMP091300	ABCB1A	Abcb1a	Rattus norvegicus (Norway rat)	Irinotecan affects the expression of ABCB1A mRNA	https://ctdbase.org/detail.go?type=gene&acc=18671
BIMP091430	ABCB1A	Abcb1a	Rattus norvegicus (Norway rat)	Dimethylnitrosamine results in increased expression of ABCB1A mRNA	https://ctdbase.org/detail.go?type=gene&acc=18671
BIMP091430	ABCB1B	Abcb1b	Rattus norvegicus (Norway rat)	Dimethylnitrosamine results in increased expression of ABCB1B mRNA	https://ctdbase.org/detail.go?type=gene&acc=18669
BIMP091300	ABCB1B	Abcb1b	Mus musculus (house mouse)	Everolimus inhibits the reaction [ABCB1B protein affects the metabolism of irinotecan]\|bis(4-nitrophenyl)phosphate inhibits the reaction [ABCB1B protein affects the metabolism of irinotecan]\|abcb1b protein affects the metabolism of irinotecan	https://ctdbase.org/detail.go?type=gene&acc=18669

BIMP082880

ABCB1A

Abcb1a

Rattus norvegicus (Norway rat)

Cyclosporine inhibits the reaction [ABCB1A protein results in increased export of risperidone]|cyclosporine results in decreased activity of ABCB1A protein|cyclosporine inhibits the reaction [ABCB1A protein results in increased export of paliperidone palmitate]