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SCFBio, IIT Delhi Hauz Khas, New Delhi
MOLECULAR TARGET

ABCB1A

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136

Interactions

Rattus norvegicus (Norway rat)

Organism

Abcb1a

Gene Name

Compound Associations

S.No BIMP ID Organism Action References
1 BIMP095241 Rattus norvegicus (Norway rat) Ethanol results in increased expression of ABCB1A mRNA
2 BIMP094500 Rattus norvegicus (Norway rat) Nonylphenol results in increased expression of ABCB1A mRNA
3 BIMP094500 Rattus norvegicus (Norway rat) Nonylphenol results in increased expression of ABCB1A mRNA
4 BIMP092603 Rattus norvegicus (Norway rat) Tert-butylhydroperoxide results in increased expression of ABCB1A mRNA
5 BIMP091430 Rattus norvegicus (Norway rat) Dimethylnitrosamine results in increased expression of ABCB1A mRNA
6 BIMP091703 Rattus norvegicus (Norway rat) Mannitol inhibits the reaction [vitamin A results in decreased expression of ABCB1A mrna]
7 BIMP091521 Rattus norvegicus (Norway rat) ABCB1A protein results in decreased susceptibility to colchicine
8 BIMP091585 Rattus norvegicus (Norway rat) Cycloheximide inhibits the reaction [tetrabromobisphenol A results in increased expression of and results in increased activity of ABCB1A protein]
9 BIMP091300 Rattus norvegicus (Norway rat) ABCB1A gene mutant form results in decreased susceptibility to irinotecan
10 BIMP091300 Rattus norvegicus (Norway rat) Everolimus inhibits the reaction [ABCB1A protein affects the metabolism of irinotecan]|bis(4-nitrophenyl)phosphate inhibits the reaction [ABCB1A protein affects the metabolism of irinotecan]|abcb1a protein affects the metabolism of irinotecan
11 BIMP091300 Rattus norvegicus (Norway rat) Irinotecan affects the expression of ABCB1A mRNA
12 BIMP096895 Rattus norvegicus (Norway rat) Coptisine results in increased expression of ABCB1A mrna|coptisine results in increased expression of ABCB1A protein|dactinomycin inhibits the reaction [coptisine results in increased expression of ABCB1A mrna]
13 BIMP100881 Rattus norvegicus (Norway rat) 1,3-butadiene results in increased expression of ABCB1A mRNA
14 BIMP098224 Rattus norvegicus (Norway rat) Prochloraz results in increased expression of ABCB1A mRNA
15 BIMP098224 Rattus norvegicus (Norway rat) Prochloraz results in increased expression of ABCB1A protein
16 BIMP098224 Rattus norvegicus (Norway rat) [cyproconazole co-treated with epoxiconazole co-treated with prochloraz] results in increased expression of ABCB1A mRNA
17 BIMP094277 Rattus norvegicus (Norway rat) [bisphenol A results in increased activity of NR1I2 protein] which results in increased expression of ABCB1A mRNA
18 BIMP094277 Rattus norvegicus (Norway rat) [NR1I2 gene results in increased susceptibility to bisphenol A] which results in increased expression of ABCB1A mRNA
19 BIMP094277 Rattus norvegicus (Norway rat) [tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with diethylhexyl phthalate co-treated with bisphenol A] results in increased expression of ABCB1A mRNA
20 BIMP094277 Rattus norvegicus (Norway rat) Bisphenol A results in decreased expression of ABCB1A mRNA
21 BIMP094277 Rattus norvegicus (Norway rat) Bisphenol A results in increased methylation of ABCB1A gene
22 BIMP093437 Rattus norvegicus (Norway rat) Cannabidiol results in increased expression of ABCB1A mRNA
23 BIMP101295 Rattus norvegicus (Norway rat) [tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with diethylhexyl phthalate co-treated with bisphenol A] results in increased expression of ABCB1A mRNA
24 BIMP101315 Rattus norvegicus (Norway rat) [vancomycin co-treated with neomycin co-treated with ampicillin co-treated with metronidazole co-treated with amphotericin B] results in increased expression of ABCB1A mRNA
25 BIMP037221 Rattus norvegicus (Norway rat) ABCB1A affects the susceptibility to dronabinol
26 BIMP037961 Rattus norvegicus (Norway rat) [perfluorooctane sulfonic acid co-treated with cellulose] results in increased expression of ABCB1A mRNA
27 BIMP064420 Rattus norvegicus (Norway rat) Aflatoxin B1 affects the expression of ABCB1A mRNA
28 BIMP064420 Rattus norvegicus (Norway rat) [sulforaphane co-treated with aflatoxin B1] affects the expression of ABCB1A mRNA
29 BIMP065112 Rattus norvegicus (Norway rat) Troleandomycin inhibits the reaction [ABCB1A protein results in increased secretion of fluorexon]
30 BIMP064585 Rattus norvegicus (Norway rat) ABCB1A protein results in increased export of palmatine|palmatine inhibits the reaction [ABCB1A protein results in increased export of fluorescent dyes]|palmatine results in increased expression of ABCB1A mRNA
31 BIMP067854 Rattus norvegicus (Norway rat) Cholic acid results in increased expression of ABCB1A mRNA
32 BIMP067854 Rattus norvegicus (Norway rat) Cholic acid results in increased expression of ABCB1A protein
33 BIMP036503 Rattus norvegicus (Norway rat) Schizandrin B inhibits the reaction [carbon tetrachloride results in increased expression of ABCB1A mrna]
34 BIMP026434 Rattus norvegicus (Norway rat) Folic acid results in decreased expression of ABCB1A mRNA
35 BIMP034250 Rattus norvegicus (Norway rat) Capsaicin results in decreased expression of ABCB1A mRNA
36 BIMP032534 Rattus norvegicus (Norway rat) [vancomycin co-treated with imipenem] results in decreased expression of ABCB1A mRNA
37 BIMP032534 Rattus norvegicus (Norway rat) [vancomycin co-treated with neomycin co-treated with ampicillin co-treated with metronidazole co-treated with amphotericin B] results in increased expression of ABCB1A mRNA
38 BIMP032534 Rattus norvegicus (Norway rat) Vancomycin results in increased expression of ABCB1A mRNA
39 BIMP032534 Rattus norvegicus (Norway rat) JBP 485 inhibits the reaction [vancomycin results in decreased expression of ABCB1A mrna]|vancomycin results in decreased expression of ABCB1A protein|vancomycin results in decreased expression of ABCB1A mrna|jbp 485 inhibits the reaction [vancomycin results in decreased expression of ABCB1A protein]
40 BIMP025809 Rattus norvegicus (Norway rat) ABCB1A protein results in increased secretion of vinblastine
41 BIMP012975 Rattus norvegicus (Norway rat) 1,9-dideoxyforskolin results in decreased activity of ABCB1A protein
42 BIMP013011 Rattus norvegicus (Norway rat) ABCB1A mutant form promotes the reaction [triptolide results in decreased expression of BCL2 protein]|abcb1a protein results in decreased susceptibility to triptolide|abcb1a mutant form promotes the reaction [triptolide results in increased expression of BAX protein]|[abcb1a mutant form co-treated with triptolide] results in increased abundance of malondialdehyde|abcb1a mutant form promotes the reaction [triptolide results in increased activity of GPT protein]
43 BIMP013011 Rattus norvegicus (Norway rat) Triptolide results in decreased expression of ABCB1A protein
44 BIMP013011 Rattus norvegicus (Norway rat) Triptolide results in increased expression of ABCB1A protein
45 BIMP016143 Rattus norvegicus (Norway rat) Toluene results in increased expression of ABCB1A mRNA
46 BIMP013961 Rattus norvegicus (Norway rat) [ABCB1A mutant form co-treated with triptolide] results in increased abundance of malondialdehyde
47 BIMP009803 Rattus norvegicus (Norway rat) Kainic acid results in increased expression of ABCB1A mrna|kainic acid results in increased expression of ABCB1A protein
48 BIMP071726 Rattus norvegicus (Norway rat) ABCB1A gene mutant form results in decreased susceptibility to diclofenac
49 BIMP071726 Rattus norvegicus (Norway rat) Diclofenac results in decreased activity of ABCB1A protein
50 BIMP072198 Rattus norvegicus (Norway rat) Valproic acid affects the expression of ABCB1A mRNA
51 BIMP072198 Rattus norvegicus (Norway rat) Valproic acid results in increased expression of ABCB1A protein
52 BIMP072198 Rattus norvegicus (Norway rat) Valproic acid results in decreased expression of ABCB1A mRNA
53 BIMP072198 Rattus norvegicus (Norway rat) Valproic acid results in increased expression of ABCB1A mRNA
54 BIMP071851 Rattus norvegicus (Norway rat) LEPR gene mutant form affects the reaction [[methionine deficiency co-treated with choline deficiency] results in increased expression of ABCB1A mrna]|[methionine deficiency co-treated with choline deficiency] results in increased expression of ABCB1A mrna|[lepr gene mutant form co-treated with methionine deficiency co-treated with choline deficiency] results in increased expression of ABCB1A protein
55 BIMP073679 Rattus norvegicus (Norway rat) 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [vitamin A results in decreased expression of ABCB1A mrna]
56 BIMP073679 Rattus norvegicus (Norway rat) 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid results in decreased expression of ABCB1A protein
57 BIMP073812 Rattus norvegicus (Norway rat) Mitotane inhibits the reaction [ABCB1A protein results in decreased susceptibility to daunorubicin]|mitotane inhibits the reaction [ABCB1A protein results in decreased susceptibility to dactinomycin]|mitotane inhibits the reaction [ABCB1A protein results in decreased susceptibility to thapsigargin]
58 BIMP075130 Rattus norvegicus (Norway rat) Notoginsenoside R1 results in increased expression of ABCB1A mRNA
59 BIMP074634 Rattus norvegicus (Norway rat) ABCB1A protein affects the susceptibility to quinidine
60 BIMP074905 Rattus norvegicus (Norway rat) ABCB1A protein affects the susceptibility to hypaconitine
61 BIMP074420 Rattus norvegicus (Norway rat) ABCB1A protein affects the susceptibility to puromycin|puromycin results in increased expression of ABCB1A protein|puromycin results in increased expression of ABCB1A mRNA
62 BIMP075559 Rattus norvegicus (Norway rat) Ochratoxin A results in decreased expression of ABCB1A mRNA
63 BIMP072777 Rattus norvegicus (Norway rat) Gentamicins results in increased expression of ABCB1A mRNA
64 BIMP072654 Rattus norvegicus (Norway rat) [[ABCB1A gene mutant form co-treated with ABCB1B gene mutant form] affects the susceptibility to fluoxetine] which affects the abundance of olanzapine|[[abcb1a gene mutant form co-treated with ABCB1B gene mutant form] affects the susceptibility to fluoxetine] which results in increased uptake of olanzapine|[abcb1a gene mutant form co-treated with ABCB1B gene mutant form] affects the susceptibility to fluoxetine
65 BIMP069171 Rattus norvegicus (Norway rat) ABCB1A gene mutant form results in decreased metabolism of and results in increased abundance of aconitine|abcb1a gene mutant form promotes the reaction [aconitine results in increased expression of S100B protein]|abcb1a gene mutant form affects the susceptibility to aconitine
66 BIMP068600 Rattus norvegicus (Norway rat) Berberine results in increased expression of ABCB1A mRNA
67 BIMP068482 Rattus norvegicus (Norway rat) Benzo(a)pyrene results in decreased expression of ABCB1A mRNA
68 BIMP070301 Rattus norvegicus (Norway rat) ABCB1A protein affects the susceptibility to verapamil
69 BIMP070301 Rattus norvegicus (Norway rat) Verapamil promotes the reaction [vanadates results in decreased activity of ABCB1A protein]
70 BIMP070301 Rattus norvegicus (Norway rat) Verapamil results in decreased activity of ABCB1A protein
71 BIMP070301 Rattus norvegicus (Norway rat) Verapamil results in decreased activity of ABCB1A protein
72 BIMP070301 Rattus norvegicus (Norway rat) Verapamil results in decreased expression of ABCB1A mRNA
73 BIMP073146 Rattus norvegicus (Norway rat) [indole-3-carbinol co-treated with diethylnitrosamine] results in increased expression of ABCB1A mRNA
74 BIMP073529 Rattus norvegicus (Norway rat) ABCB1A protein affects the susceptibility to loratadine
75 BIMP073251 Rattus norvegicus (Norway rat) Isoproterenol results in increased expression of ABCB1A mRNA
76 BIMP072264 Rattus norvegicus (Norway rat) Ursodeoxycholic acid results in increased expression of ABCB1A mRNA
77 BIMP072262 Rattus norvegicus (Norway rat) Tetrachloroethylene results in increased expression of ABCB1A mRNA
78 BIMP072300 Rattus norvegicus (Norway rat) ABCB1A gene mutant form results in increased susceptibility to doxorubicin
79 BIMP072300 Rattus norvegicus (Norway rat) ABCB1A protein affects the transport of doxorubicin
80 BIMP072300 Rattus norvegicus (Norway rat) ABCB1A protein results in increased export of doxorubicin
81 BIMP072300 Rattus norvegicus (Norway rat) ABCB1A protein results in increased secretion of doxorubicin|lipopolysaccharides affects the reaction [ABCB1A protein results in increased secretion of doxorubicin]
82 BIMP072300 Rattus norvegicus (Norway rat) [doxorubicin co-treated with polyisohexylcyanoacrylate] results in increased expression of ABCB1A mrna|doxorubicin results in increased expression of ABCB1A mRNA
83 BIMP072300 Rattus norvegicus (Norway rat) Doxorubicin results in increased expression of ABCB1A protein|doxorubicin promotes the reaction [CEBPB protein alternative form promotes the reaction [[chloroquine co-treated with bortezomib] results in decreased expression of ABCB1A protein]]
84 BIMP071142 Rattus norvegicus (Norway rat) Chloroquine promotes the reaction [bortezomib results in decreased expression of and results in increased nitrosation of ABCB1A protein]|cebpb protein alternative form promotes the reaction [[chloroquine co-treated with bortezomib] results in decreased expression of ABCB1A protein]|chloroquine results in decreased expression of and results in increased nitrosation of ABCB1A protein|chloroquine results in decreased expression of ABCB1A mrna|bortezomib promotes the reaction [chloroquine results in decreased expression of ABCB1A mrna]|chloroquine promotes the reaction [bortezomib results in decreased expression of ABCB1A mrna]|[chloroquine co-treated with bortezomib] results in decreased expression of ABCB1A protein|bortezomib promotes the reaction [chloroquine results in decreased expression of and results in increased nitrosation of ABCB1A protein]|doxorubicin promotes the reaction [CEBPB protein alternative form promotes the reaction [[chloroquine co-treated with bortezomib] results in decreased expression of ABCB1A protein]]
85 BIMP071289 Rattus norvegicus (Norway rat) PPARA promotes the reaction [clofibrate results in increased expression of ABCB1A protein]|clofibrate results in increased expression of ABCB1A mrna|clofibrate results in increased expression of ABCB1A protein|ppara promotes the reaction [clofibrate results in increased expression of ABCB1A mrna]
86 BIMP071289 Rattus norvegicus (Norway rat) Clofibrate affects the expression of ABCB1A mRNA
87 BIMP071304 Rattus norvegicus (Norway rat) Clotrimazole inhibits the reaction [ABCB1A protein results in increased secretion of fluorexon]
88 BIMP071247 Rattus norvegicus (Norway rat) Ciprofibrate results in increased expression of ABCB1A mRNA
89 BIMP071166 Rattus norvegicus (Norway rat) ABCB1A protein affects the uptake of digoxin
90 BIMP071166 Rattus norvegicus (Norway rat) ABCB1A protein results in increased uptake of digoxin
91 BIMP071583 Rattus norvegicus (Norway rat) Amphetamine results in decreased expression of ABCB1A mRNA
92 BIMP071712 Rattus norvegicus (Norway rat) Mitotane inhibits the reaction [ABCB1A protein results in decreased susceptibility to daunorubicin]|abcb1a protein results in decreased susceptibility to daunorubicin
93 BIMP071712 Rattus norvegicus (Norway rat) Cyclosporine inhibits the reaction [ABCB1A protein results in increased export of daunorubicin]|abcb1a protein results in increased export of daunorubicin
94 BIMP071712 Rattus norvegicus (Norway rat) ABCB1A affects the susceptibility to daunorubicin
95 BIMP090429 Rattus norvegicus (Norway rat) Dexamethasone inhibits the reaction [lipopolysaccharides results in decreased expression of ABCB1A mrna]
96 BIMP090429 Rattus norvegicus (Norway rat) Dexamethasone results in decreased expression of ABCB1A mRNA
97 BIMP090429 Rattus norvegicus (Norway rat) Dexamethasone results in increased expression of ABCB1A protein|dexamethasone results in increased expression of ABCB1A mRNA
98 BIMP089937 Rattus norvegicus (Norway rat) Pirinixic acid results in increased expression of ABCB1A mRNA
99 BIMP089937 Rattus norvegicus (Norway rat) Pirinixic acid affects the expression of ABCB1A mRNA
100 BIMP078749 Rattus norvegicus (Norway rat) ABCB1A gene mutant form affects the transport of and results in increased abundance of huperzine A
101 BIMP079116 Rattus norvegicus (Norway rat) ABCB1A protein results in increased transport of nortriptyline metabolite|abcb1a protein results in increased transport of nortriptyline
102 BIMP079668 Rattus norvegicus (Norway rat) Benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [isoborneol results in decreased expression of ABCB1A protein]
103 BIMP077156 Rattus norvegicus (Norway rat) 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [vitamin A results in decreased expression of ABCB1A mrna]|mannitol inhibits the reaction [vitamin A results in decreased expression of ABCB1A mrna]|vitamin A results in decreased expression of ABCB1A mRNA
104 BIMP078516 Rattus norvegicus (Norway rat) Nevirapine results in increased expression of ABCB1A mRNA
105 BIMP089333 Rattus norvegicus (Norway rat) Mifepristone results in increased expression of ABCB1A mRNA
106 BIMP086637 Rattus norvegicus (Norway rat) [sulforaphane co-treated with aflatoxin B1] affects the expression of ABCB1A mRNA
107 BIMP086637 Rattus norvegicus (Norway rat) Sulforaphane inhibits the reaction [genistein results in increased expression of ABCB1A mrna]
108 BIMP087829 Rattus norvegicus (Norway rat) ABCB1A protein results in decreased susceptibility to vincristine
109 BIMP087829 Rattus norvegicus (Norway rat) Vincristine results in increased expression of ABCB1A mRNA
110 BIMP088640 Rattus norvegicus (Norway rat) Ascorbic acid inhibits the reaction [abamectin results in increased expression of ABCB1A mrna]|[ascorbic acid co-treated with sesame oil] inhibits the reaction [abamectin results in increased expression of ABCB1A mrna]
111 BIMP082958 Rattus norvegicus (Norway rat) [morphine co-treated with naloxone] results in increased expression of ABCB1A mRNA
112 BIMP082880 Rattus norvegicus (Norway rat) ABCB1A protein results in increased transport of cyclosporine
113 BIMP082880 Rattus norvegicus (Norway rat) Cyclosporine inhibits the reaction [ABCB1A protein results in increased export of technetium tc 99m sestamibi]|cyclosporine inhibits the reaction [ABCB1A protein results in increased export of daunorubicin]
114 BIMP082880 Rattus norvegicus (Norway rat) ABCB1A protein affects the susceptibility to [pentobarbital co-treated with cyclosporine]
115 BIMP082880 Rattus norvegicus (Norway rat) Cyclosporine results in decreased activity of ABCB1A protein|abcb1a protein results in increased export of cyclosporine
116 BIMP082880 Rattus norvegicus (Norway rat) Cyclosporine inhibits the reaction [ABCB1A protein results in increased secretion of fluorexon]
117 BIMP082880 Rattus norvegicus (Norway rat) Cyclosporine results in increased expression of ABCB1A mRNA
118 BIMP082880 Rattus norvegicus (Norway rat) Cyclosporine inhibits the reaction [ABCB1A protein results in increased export of risperidone]|cyclosporine results in decreased activity of ABCB1A protein|cyclosporine inhibits the reaction [ABCB1A protein results in increased export of paliperidone palmitate]
119 BIMP082896 Rattus norvegicus (Norway rat) Oxycodone results in increased expression of ABCB1A protein|oxycodone results in increased expression of ABCB1A mRNA
120 BIMP082885 Rattus norvegicus (Norway rat) T-2 toxin results in decreased expression of ABCB1A mRNA
121 BIMP082895 Rattus norvegicus (Norway rat) [morphine co-treated with naloxone] results in increased expression of ABCB1A mRNA
122 BIMP090535 Rattus norvegicus (Norway rat) Estradiol results in decreased expression of ABCB1A mRNA
123 BIMP090535 Rattus norvegicus (Norway rat) Estradiol results in decreased expression of ABCB1A mRNA
124 BIMP082232 Rattus norvegicus (Norway rat) [vancomycin co-treated with neomycin co-treated with ampicillin co-treated with metronidazole co-treated with amphotericin B] results in increased expression of ABCB1A mRNA
125 BIMP082231 Rattus norvegicus (Norway rat) Genistein results in increased expression of ABCB1A mrna|sulforaphane inhibits the reaction [genistein results in increased expression of ABCB1A mrna]|ketoconazole inhibits the reaction [genistein results in increased expression of ABCB1A mrna]|nr1i2 protein affects the reaction [genistein results in increased expression of ABCB1A mrna]
126 BIMP082446 Rattus norvegicus (Norway rat) Fulvestrant inhibits the reaction [zearalenone results in increased expression of ABCB1A mrna]
127 BIMP082446 Rattus norvegicus (Norway rat) Zearalenone affects the expression of ABCB1A protein
128 BIMP082446 Rattus norvegicus (Norway rat) Zearalenone results in decreased expression of ABCB1A mRNA
129 BIMP082446 Rattus norvegicus (Norway rat) Zearalenone results in increased expression of ABCB1A mRNA
130 BIMP090994 Rattus norvegicus (Norway rat) [rifampin metabolite results in decreased activity of ABCB1A protein] which results in decreased abundance of adenosine triphosphate
131 BIMP091055 Rattus norvegicus (Norway rat) [dietary fats co-treated with dietary sucrose] results in increased expression of ABCB1A mRNA
132 BIMP090555 Rattus norvegicus (Norway rat) Reserpine inhibits the reaction [ABCB1A protein results in increased secretion of fluorexon]
133 BIMP090599 Rattus norvegicus (Norway rat) Piperonyl butoxide results in increased expression of ABCB1A mRNA
134 BIMP091061 Rattus norvegicus (Norway rat) Ethinyl estradiol affects the expression of ABCB1A mRNA
135 BIMP091061 Rattus norvegicus (Norway rat) [tetrachlorodibenzodioxin co-treated with ethinyl estradiol] results in decreased expression of ABCB1A mrna|ethinyl estradiol results in decreased expression of ABCB1A mRNA
136 BIMP091061 Rattus norvegicus (Norway rat) Ethinyl estradiol results in decreased expression of ABCB1A mRNA