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Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
Abcb1a
|
Mus musculus (house mouse)
|
[vancomycin co-treated with imipenem] results in decreased expression of ABCB1A mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Mus musculus (house mouse)
|
[vancomycin co-treated with neomycin co-treated with ampicillin co-treated with metronidazole co-treated with amphotericin B] results in increased expression of ABCB1A mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Mus musculus (house mouse)
|
Vancomycin results in increased expression of ABCB1A mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Rattus norvegicus (Norway rat)
|
JBP 485 inhibits the reaction [vancomycin results in decreased expression of ABCB1A mrna]|vancomycin results in decreased expression of ABCB1A protein|vancomycin results in decreased expression of ABCB1A mrna|jbp 485 inhibits the reaction [vancomycin results in decreased expression of ABCB1A protein]
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Mus musculus (house mouse)
|
ABCB1A protein results in increased secretion of vinblastine
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Mus musculus (house mouse)
|
Valproic acid affects the expression of ABCB1A mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Mus musculus (house mouse)
|
Valproic acid results in increased expression of ABCB1A protein
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Rattus norvegicus (Norway rat)
|
Valproic acid results in decreased expression of ABCB1A mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Rattus norvegicus (Norway rat)
|
Valproic acid results in increased expression of ABCB1A mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Rattus norvegicus (Norway rat)
|
[indole-3-carbinol co-treated with diethylnitrosamine] results in increased expression of ABCB1A mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Rattus norvegicus (Norway rat)
|
Gentamicins results in increased expression of ABCB1A mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Rattus norvegicus (Norway rat)
|
[[ABCB1A gene mutant form co-treated with ABCB1B gene mutant form] affects the susceptibility to fluoxetine] which affects the abundance of olanzapine|[[abcb1a gene mutant form co-treated with ABCB1B gene mutant form] affects the susceptibility to fluoxetine] which results in increased uptake of olanzapine|[abcb1a gene mutant form co-treated with ABCB1B gene mutant form] affects the susceptibility to fluoxetine
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Rattus norvegicus (Norway rat)
|
Ursodeoxycholic acid results in increased expression of ABCB1A mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Mus musculus (house mouse)
|
ABCB1A gene mutant form results in increased susceptibility to doxorubicin
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Mus musculus (house mouse)
|
ABCB1A protein affects the transport of doxorubicin
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Mus musculus (house mouse)
|
ABCB1A protein results in increased export of doxorubicin
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Mus musculus (house mouse)
|
ABCB1A protein results in increased secretion of doxorubicin|lipopolysaccharides affects the reaction [ABCB1A protein results in increased secretion of doxorubicin]
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Mus musculus (house mouse)
|
[doxorubicin co-treated with polyisohexylcyanoacrylate] results in increased expression of ABCB1A mrna|doxorubicin results in increased expression of ABCB1A mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Mus musculus (house mouse)
|
Doxorubicin results in increased expression of ABCB1A protein|doxorubicin promotes the reaction [CEBPB protein alternative form promotes the reaction [[chloroquine co-treated with bortezomib] results in decreased expression of ABCB1A protein]]
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Mus musculus (house mouse)
|
Tetrachloroethylene results in increased expression of ABCB1A mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Mus musculus (house mouse)
|
ABCB1A gene mutant form results in decreased metabolism of and results in increased abundance of aconitine|abcb1a gene mutant form promotes the reaction [aconitine results in increased expression of S100B protein]|abcb1a gene mutant form affects the susceptibility to aconitine
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Mus musculus (house mouse)
|
ABCB1A protein affects the susceptibility to verapamil
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Mus musculus (house mouse)
|
Verapamil promotes the reaction [vanadates results in decreased activity of ABCB1A protein]
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Mus musculus (house mouse)
|
Verapamil results in decreased activity of ABCB1A protein
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Rattus norvegicus (Norway rat)
|
Verapamil results in decreased activity of ABCB1A protein
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
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