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Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
Abcb1a
|
Rattus norvegicus (Norway rat)
|
Coptisine results in increased expression of ABCB1A mrna|coptisine results in increased expression of ABCB1A protein|dactinomycin inhibits the reaction [coptisine results in increased expression of ABCB1A mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Mus musculus (house mouse)
|
1,3-butadiene results in increased expression of ABCB1A mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Mus musculus (house mouse)
|
Tert-butylhydroperoxide results in increased expression of ABCB1A mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Cricetulus griseus (Chinese hamster)
|
ABCB1A protein results in decreased susceptibility to colchicine
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Rattus norvegicus (Norway rat)
|
Mannitol inhibits the reaction [vitamin A results in decreased expression of ABCB1A mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Rattus norvegicus (Norway rat)
|
Cycloheximide inhibits the reaction [tetrabromobisphenol A results in increased expression of and results in increased activity of ABCB1A protein]
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Mus musculus (house mouse)
|
Cannabidiol results in increased expression of ABCB1A mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Mus musculus (house mouse)
|
ABCB1A affects the susceptibility to dronabinol
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Mus musculus (house mouse)
|
[perfluorooctane sulfonic acid co-treated with cellulose] results in increased expression of ABCB1A mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Mus musculus (house mouse)
|
Cholic acid results in increased expression of ABCB1A mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Mus musculus (house mouse)
|
Cholic acid results in increased expression of ABCB1A protein
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Rattus norvegicus (Norway rat)
|
1,9-dideoxyforskolin results in decreased activity of ABCB1A protein
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Mus musculus (house mouse)
|
ABCB1A mutant form promotes the reaction [triptolide results in decreased expression of BCL2 protein]|abcb1a protein results in decreased susceptibility to triptolide|abcb1a mutant form promotes the reaction [triptolide results in increased expression of BAX protein]|[abcb1a mutant form co-treated with triptolide] results in increased abundance of malondialdehyde|abcb1a mutant form promotes the reaction [triptolide results in increased activity of GPT protein]
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Rattus norvegicus (Norway rat)
|
Triptolide results in decreased expression of ABCB1A protein
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Rattus norvegicus (Norway rat)
|
Triptolide results in increased expression of ABCB1A protein
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Mus musculus (house mouse)
|
[ABCB1A mutant form co-treated with triptolide] results in increased abundance of malondialdehyde
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Rattus norvegicus (Norway rat)
|
Toluene results in increased expression of ABCB1A mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Rattus norvegicus (Norway rat)
|
Kainic acid results in increased expression of ABCB1A mrna|kainic acid results in increased expression of ABCB1A protein
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Mus musculus (house mouse)
|
Aflatoxin B1 affects the expression of ABCB1A mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Rattus norvegicus (Norway rat)
|
[sulforaphane co-treated with aflatoxin B1] affects the expression of ABCB1A mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Mus musculus (house mouse)
|
Troleandomycin inhibits the reaction [ABCB1A protein results in increased secretion of fluorexon]
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Mus musculus (house mouse)
|
ABCB1A protein results in increased export of palmatine|palmatine inhibits the reaction [ABCB1A protein results in increased export of fluorescent dyes]|palmatine results in increased expression of ABCB1A mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Rattus norvegicus (Norway rat)
|
Capsaicin results in decreased expression of ABCB1A mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Rattus norvegicus (Norway rat)
|
Schizandrin B inhibits the reaction [carbon tetrachloride results in increased expression of ABCB1A mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
||
|
Abcb1a
|
Mus musculus (house mouse)
|
Folic acid results in decreased expression of ABCB1A mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=18671
|
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