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Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
ABCB1
|
Homo sapiens (human)
|
|
https://www.dgidb.org/genes/hgnc:40
|
||
|
ABCB1
|
Homo sapiens (human)
|
Acetylcysteine inhibits the reaction [formononetin results in increased expression of ABCB1 mrna]|formononetin results in increased expression of ABCB1 mrna|formononetin inhibits the reaction [epirubicin results in increased expression of ABCB1 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
Formononetin affects the activity of ABCB1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
Formononetin promotes the reaction [elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of rhodamine 123]]
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Mus musculus (house mouse)
|
Formononetin results in decreased activity of ABCB1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
Genistein results in increased expression of ABCB1 mrna|fulvestrant inhibits the reaction [genistein results in increased expression of ABCB1 protein]|genistein results in increased expression of and results in increased activity of ABCB1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
Genistein results in decreased expression of ABCB1 protein|genistein promotes the reaction [ABCB1 protein results in decreased uptake of rhodamine 123]|genistein promotes the reaction [quercetin results in increased activity of ABCB1 protein]|genistein results in increased activity of ABCB1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
Genistein results in increased expression of ABCB1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
ABCB1 protein results in increased export of retrorsine|cyclosporine inhibits the reaction [ABCB1 protein results in increased export of retrorsine]
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
Puerarin inhibits the reaction [ABCB1 protein results in decreased uptake of daunorubicin]
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
[ginkgolic acid affects the activity of ABCB1 protein] which results in increased abundance of daunorubicin
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
Tectochrysin inhibits the reaction [ABCB1 protein results in decreased susceptibility to paclitaxel]|abcb1 protein results in decreased susceptibility to tectochrysin|tectochrysin results in decreased activity of ABCB1 protein|tectochrysin inhibits the reaction [ABCB1 protein results in decreased susceptibility to docetaxel]|[tectochrysin results in decreased activity of ABCB1 protein] which results in decreased export of calcein am|tectochrysin inhibits the reaction [ABCB1 protein results in decreased susceptibility to vincristine]
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
ABCB1 protein results in increased export of anandamide
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
Tocotrienol, alpha results in increased expression of ABCB1
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
Tocotrienol, beta results in increased expression of ABCB1
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
Tocotrienol, delta results in increased expression of ABCB1
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
|
https://www.dgidb.org/genes/hgnc:40
|
||
|
ABCB1
|
Mus musculus (house mouse)
|
Senecionine results in decreased expression of ABCB1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Canis lupus familiaris (dog)
|
Kaempferol inhibits the reaction [ABCB1 protein results in increased secretion of ritonavir]
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
ABCB1 protein results in increased transport of kaempferol
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
Kaempferol inhibits the reaction [[ABCB1 protein results in decreased susceptibility to doxorubicin] promotes the reaction [tetradecanoylphorbol acetate results in increased expression of ABCB1 mrna]]
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
Kaempferol inhibits the reaction [ABCB1 protein results in decreased uptake of daunorubicin]|kaempferol results in increased activity of ABCB1 protein|kaempferol inhibits the reaction [ABCB1 protein results in decreased uptake of rhodamine 123]|verapamil promotes the reaction [kaempferol results in increased activity of ABCB1 protein]
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
Kaempferol results in decreased expression of ABCB1 protein|kaempferol results in decreased expression of ABCB1 mrna|[verapamil co-treated with kaempferol] results in decreased expression of ABCB1 mrna|[verapamil co-treated with kaempferol] results in decreased expression of ABCB1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
Rescinnamine results in increased expression of ABCB1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
Baicalein inhibits the reaction [ABCB1 protein results in decreased uptake of daunorubicin]|baicalein inhibits the reaction [ABCB1 protein results in decreased uptake of rhodamine 123]|baicalein inhibits the reaction [elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of daunorubicin]]|baicalein promotes the reaction [elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of rhodamine 123]]|baicalein results in increased expression of ABCB1 protein|baicalein results in increased activity of ABCB1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
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