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SCFBio, IIT Delhi Hauz Khas, New Delhi

Molecular Targets

Interactions between compounds and specific gene/protein targets.

Total Rows 750,454
Pages 30,019
BIMP_ID Target Name Gene Organism Action Source URL
ABCB1
Homo sapiens (human)
Baicalein results in increased expression of ABCB1 mRNA
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Homo sapiens (human)
Galangin results in increased activity of ABCB1 protein|galangin inhibits the reaction [elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of daunorubicin]]|verapamil promotes the reaction [galangin results in increased activity of ABCB1 protein]|galangin results in increased expression of ABCB1 protein
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Homo sapiens (human)
Galangin results in increased expression of ABCB1 mRNA
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Rattus norvegicus (Norway rat)
Zearalenone results in increased expression of ABCB1 mRNA
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Homo sapiens (human)
Cucurbitacin I inhibits the reaction [ABCB1 protein results in increased uptake of digoxin]
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Homo sapiens (human)
Ophiobolin A inhibits the reaction [ABCB1 protein results in increased uptake of digoxin]
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Homo sapiens (human)
Chrysin affects the activity of ABCB1 protein
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Homo sapiens (human)
Chrysin results in decreased activity of ABCB1 protein|chrysin results in increased expression of ABCB1 protein|[chrysin results in decreased activity of ABCB1 protein] which results in decreased export of topotecan
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Mus musculus (house mouse)
Chrysin results in decreased activity of ABCB1 protein
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Homo sapiens (human)
Daidzein inhibits the reaction [elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of rhodamine 123]]
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Homo sapiens (human)
Myricetin results in increased activity of ABCB1 protein|myricetin inhibits the reaction [ABCB1 protein results in decreased uptake of rhodamine 123]|myricetin results in increased expression of ABCB1 protein
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Homo sapiens (human)
Sciadopitysin results in decreased activity of ABCB1 protein|sciadopitysin inhibits the reaction [ABCB1 protein results in increased transport of digoxin]
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Homo sapiens (human)
Tamarixetin results in increased expression of ABCB1 mRNA
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Homo sapiens (human)
Mangiferin results in increased expression of ABCB1 protein|dichlororibofuranosylbenzimidazole inhibits the reaction [mangiferin results in increased expression of ABCB1 protein]|mangiferin results in increased expression of ABCB1 mRNA
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Homo sapiens (human)
3-methylquercetin results in increased activity of ABCB1 protein|3-methylquercetin inhibits the reaction [ABCB1 protein results in decreased uptake of rhodamine 123]|3-methylquercetin results in decreased expression of ABCB1 protein|3-methylquercetin promotes the reaction [elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of rhodamine 123]]|3-methylquercetin promotes the reaction [quercetin results in increased activity of ABCB1 protein]
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Homo sapiens (human)
3-methylquercetin results in increased expression of ABCB1 mRNA
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Homo sapiens (human)
ABCB1 protein results in increased transport of 3-methylquercetin
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Homo sapiens (human)
Norathyriol results in increased expression of ABCB1 protein
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Homo sapiens (human)
Kaempferide inhibits the reaction [elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of daunorubicin]]|kaempferide inhibits the reaction [ABCB1 protein results in decreased uptake of daunorubicin]
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Mus musculus (house mouse)
Kuwanon G results in increased expression of ABCB1 protein|kuwanon G results in increased expression of ABCB1 mrna|geranylgeranyl pyrophosphate inhibits the reaction [kuwanon G results in increased expression of ABCB1 protein]
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Homo sapiens (human)
Morin promotes the reaction [quercetin results in increased activity of ABCB1 protein]|morin results in increased activity of ABCB1 protein
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Homo sapiens (human)
ABCB1 protein results in increased transport of proscillaridin
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Homo sapiens (human)
Proscillaridin inhibits the reaction [ABCB1 protein results in increased transport of quinidinium]
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Homo sapiens (human)
Ascorbic acid inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCB1 mrna]|cat protein inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCB1 mrna]|acetylcysteine inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCB1 mrna]|3',4',7-trihydroxyisoflavone inhibits the reaction [epirubicin results in increased expression of ABCB1 mrna]|3',4',7-trihydroxyisoflavone results in decreased expression of ABCB1 mRNA
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Homo sapiens (human)
5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one inhibits the reaction [ABCB1 protein results in increased transport of digoxin]|5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one results in decreased activity of ABCB1 protein
https://ctdbase.org/detail.go?type=gene&acc=5243
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