SCFBio, IIT Delhi
Hauz Khas, New Delhi
BIMP
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SCFBio, IIT Delhi
Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
ABCB1
|
Homo sapiens (human)
|
5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one results in decreased expression of ABCB1 mrna|5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one results in decreased expression of and results in decreased activity of ABCB1 protein|diacetyldiphenylurea bisguanylhydrazone inhibits the reaction [5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one results in decreased expression of ABCB1 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
Sulforaphane inhibits the reaction [ginkgolide B results in increased expression of ABCB1 mrna]|sulforaphane results in decreased expression of ABCB1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
|
https://www.dgidb.org/genes/hgnc:40
|
||
|
ABCB1
|
Homo sapiens (human)
|
|
https://www.dgidb.org/genes/hgnc:40
|
||
|
ABCB1
|
Homo sapiens (human)
|
ABCB1 affects the metabolism of morphine
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
Glycitein promotes the reaction [elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of rhodamine 123]]|glycitein promotes the reaction [elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of daunorubicin]]|glycitein inhibits the reaction [ABCB1 protein results in decreased uptake of daunorubicin]
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
|
https://www.dgidb.org/genes/hgnc:40
|
||
|
ABCB1
|
Rattus norvegicus (Norway rat)
|
Naloxone results in increased expression of ABCB1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Canis lupus familiaris (dog)
|
Valspodar inhibits the reaction [ABCB1 protein affects the susceptibility to vincristine]|abcb1 protein affects the susceptibility to vincristine
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Canis lupus familiaris (dog)
|
ABCB1 protein results in increased export of vincristine
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
ABCB1 protein affects the susceptibility to vincristine
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
ABCB1 protein affects the uptake of vincristine
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
ABCB1 protein results in decreased susceptibility to vincristine
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
ABCB1 protein results in decreased uptake of vincristine
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
Fenofibrate inhibits the reaction [ABCB1 protein results in increased transport of vincristine]|abcb1 protein results in increased transport of vincristine
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
CEP 33779 inhibits the reaction [ABCB1 protein results in decreased susceptibility to vincristine]|verapamil inhibits the reaction [ABCB1 protein results in decreased susceptibility to vincristine]
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
Cyclosporine inhibits the reaction [ABCB1 protein results in decreased susceptibility to vincristine]|flupenthixol analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to vincristine]
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
[estradiol results in decreased expression of ABCB1 protein] which results in increased uptake of and results in increased susceptibility to vincristine
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
[MGMT protein co-treated with ABCB1 protein] results in decreased susceptibility to vincristine
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
NR1I2 protein promotes the reaction [vincristine results in increased expression of ABCB1 protein]|[vincristine results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
[paclitaxel results in increased expression of ABCB1] which results in decreased susceptibility to vincristine
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
Tectochrysin inhibits the reaction [ABCB1 protein results in decreased susceptibility to vincristine]|pinostrobin inhibits the reaction [ABCB1 protein results in decreased susceptibility to vincristine]
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
[vincristine results in decreased susceptibility to vincristine] which affects the expression of ABCB1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
Vincristine results in increased expression of ABCB1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
Zosuquidar trihydrochloride inhibits the reaction [ABCB1 protein results in decreased susceptibility to vincristine]
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
No matching records found on this page.