Molecular Targets : Dataset Browser

BIMP_ID	Target Name	Gene	Organism	Action	Source URL
BIMP087829	ABCB1	ABCB1	Homo sapiens (human)	ABCB1 results in decreased susceptibility to vincristine	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP087829	ABCB1	ABCB1	Homo sapiens (human)		https://www.dgidb.org/genes/hgnc:40
BIMP087871	ABCB1	ABCB1	Homo sapiens (human)	Cardenolides inhibits the reaction [ABCB1 protein results in increased transport of quinidinium]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP082880	ABCB1	ABCB1	Drosophila melanogaster (fruit fly)	[cyclosporine results in decreased activity of ABCB1 protein] inhibits the reaction [avermectin results in increased abundance of calcium]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP082880	ABCB1	ABCB1	Homo sapiens (human)	ABCB1 protein affects the export of cyclosporine	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP082880	ABCB1	ABCB1	Homo sapiens (human)	ABCB1 protein affects the susceptibility to cyclosporine	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP082880	ABCB1	ABCB1	Homo sapiens (human)	ABCB1 protein affects the transport of cyclosporine	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP082880	ABCB1	ABCB1	Homo sapiens (human)	ABCB1 protein polymorphism affects the susceptibility to cyclosporine	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP082880	ABCB1	ABCB1	Homo sapiens (human)	ABCB1 protein results in increased transport of cyclosporine	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP082880	ABCB1	ABCB1	Homo sapiens (human)	Cyclosporine affects the expression of ABCB1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP082880	ABCB1	ABCB1	Homo sapiens (human)	[cyclosporine binds to and results in decreased activity of ABCB1 protein] which results in decreased export of digoxin\|cyclosporine binds to and results in decreased activity of ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP082880	ABCB1	ABCB1	Homo sapiens (human)	[cyclosporine co-treated with raloxifene hydrochloride] results in decreased expression of ABCB1 mrna\|[cyclosporine co-treated with raloxifene hydrochloride] results in decreased expression of ABCB1 protein\|cyclosporine results in decreased expression of ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP082880	ABCB1	ABCB1	Homo sapiens (human)	Cyclosporine inhibits the reaction [ABCB1 protein affects the export of calcein AM]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP082880	ABCB1	ABCB1	Homo sapiens (human)	Cyclosporine inhibits the reaction [ABCB1 protein results in decreased susceptibility to doxorubicin]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP082880	ABCB1	ABCB1	Homo sapiens (human)	Cyclosporine inhibits the reaction [ABCB1 protein results in decreased susceptibility to vincristine]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP082880	ABCB1	ABCB1	Homo sapiens (human)	Cyclosporine inhibits the reaction [ABCB1 protein results in decreased uptake of doxorubicin]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP082880	ABCB1	ABCB1	Homo sapiens (human)	Cyclosporine inhibits the reaction [ABCB1 protein results in increased chemical synthesis of glucosylceramides]\|cyclosporine inhibits the reaction [ABCB1 protein results in increased chemical synthesis of lactosylceramides]\|cyclosporine inhibits the reaction [ABCB1 protein results in increased chemical synthesis of globotriaosylceramide]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP082880	ABCB1	ABCB1	Homo sapiens (human)	Cyclosporine inhibits the reaction [ABCB1 protein results in increased export of daunorubicin]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP082880	ABCB1	ABCB1	Homo sapiens (human)	Cyclosporine inhibits the reaction [ABCB1 protein results in increased export of diazinon]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP082880	ABCB1	ABCB1	Homo sapiens (human)	Cyclosporine inhibits the reaction [ABCB1 protein results in increased export of fluorescent dyes]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP082880	ABCB1	ABCB1	Homo sapiens (human)	Cyclosporine inhibits the reaction [ABCB1 protein results in increased secretion of vinblastine]\|cyclosporine inhibits the reaction [ABCB1 protein results in increased secretion of fluorexon]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP082880	ABCB1	ABCB1	Homo sapiens (human)	Cyclosporine inhibits the reaction [verapamil analog results in increased activity of ABCB1 protein mutant form]\|cyclosporine results in decreased activity of ABCB1 protein mutant form	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP082880	ABCB1	ABCB1	Homo sapiens (human)	Cyclosporine results in decreased activity of ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP082880	ABCB1	ABCB1	Homo sapiens (human)	[cyclosporine results in decreased activity of ABCB1 protein] which results in decreased transport of benzoylaconine\|[cyclosporine results in decreased activity of ABCB1 protein] which results in decreased transport of benzoylmesaconine\|[cyclosporine results in decreased activity of ABCB1 protein] which results in decreased transport of mesaconitine\|[cyclosporine results in decreased activity of ABCB1 protein] which results in decreased transport of benzoylhypaconine\|[cyclosporine results in decreased activity of ABCB1 protein] which results in decreased transport of hypaconitine	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP082880	ABCB1	ABCB1	Homo sapiens (human)	[cyclosporine results in decreased activity of ABCB1 protein] which results in increased susceptibility to paclitaxel	https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP087829

ABCB1

Homo sapiens (human)

ABCB1 results in decreased susceptibility to vincristine

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP087829

ABCB1

Homo sapiens (human)

https://www.dgidb.org/genes/hgnc:40

BIMP087871

ABCB1

Homo sapiens (human)

Cardenolides inhibits the reaction [ABCB1 protein results in increased transport of quinidinium]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP082880

ABCB1

Drosophila melanogaster (fruit fly)

[cyclosporine results in decreased activity of ABCB1 protein] inhibits the reaction [avermectin results in increased abundance of calcium]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP082880

ABCB1

Homo sapiens (human)

ABCB1 protein affects the export of cyclosporine

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP082880

ABCB1

Homo sapiens (human)

ABCB1 protein affects the susceptibility to cyclosporine

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP082880

ABCB1

Homo sapiens (human)

ABCB1 protein affects the transport of cyclosporine

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP082880

ABCB1

Homo sapiens (human)

ABCB1 protein polymorphism affects the susceptibility to cyclosporine

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP082880

ABCB1

Homo sapiens (human)

ABCB1 protein results in increased transport of cyclosporine

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP082880

ABCB1

Homo sapiens (human)

Cyclosporine affects the expression of ABCB1 mRNA

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP082880

ABCB1

Homo sapiens (human)

[cyclosporine binds to and results in decreased activity of ABCB1 protein] which results in decreased export of digoxin|cyclosporine binds to and results in decreased activity of ABCB1 protein

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP082880

ABCB1

Homo sapiens (human)

[cyclosporine co-treated with raloxifene hydrochloride] results in decreased expression of ABCB1 mrna|[cyclosporine co-treated with raloxifene hydrochloride] results in decreased expression of ABCB1 protein|cyclosporine results in decreased expression of ABCB1 protein

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP082880

ABCB1

Homo sapiens (human)

Cyclosporine inhibits the reaction [ABCB1 protein affects the export of calcein AM]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP082880

ABCB1

Homo sapiens (human)

Cyclosporine inhibits the reaction [ABCB1 protein results in decreased susceptibility to doxorubicin]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP082880

ABCB1

Homo sapiens (human)

Cyclosporine inhibits the reaction [ABCB1 protein results in decreased susceptibility to vincristine]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP082880

ABCB1

Homo sapiens (human)

Cyclosporine inhibits the reaction [ABCB1 protein results in decreased uptake of doxorubicin]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP082880

ABCB1

Homo sapiens (human)

Cyclosporine inhibits the reaction [ABCB1 protein results in increased chemical synthesis of glucosylceramides]|cyclosporine inhibits the reaction [ABCB1 protein results in increased chemical synthesis of lactosylceramides]|cyclosporine inhibits the reaction [ABCB1 protein results in increased chemical synthesis of globotriaosylceramide]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP082880

ABCB1

Homo sapiens (human)

Cyclosporine inhibits the reaction [ABCB1 protein results in increased export of daunorubicin]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP082880

ABCB1

Homo sapiens (human)

Cyclosporine inhibits the reaction [ABCB1 protein results in increased export of diazinon]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP082880

ABCB1

Homo sapiens (human)

Cyclosporine inhibits the reaction [ABCB1 protein results in increased export of fluorescent dyes]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP082880

ABCB1

Homo sapiens (human)

Cyclosporine inhibits the reaction [ABCB1 protein results in increased secretion of vinblastine]|cyclosporine inhibits the reaction [ABCB1 protein results in increased secretion of fluorexon]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP082880

ABCB1

Homo sapiens (human)

Cyclosporine inhibits the reaction [verapamil analog results in increased activity of ABCB1 protein mutant form]|cyclosporine results in decreased activity of ABCB1 protein mutant form

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP082880

ABCB1

Homo sapiens (human)

Cyclosporine results in decreased activity of ABCB1 protein

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP082880

ABCB1

Homo sapiens (human)

[cyclosporine results in decreased activity of ABCB1 protein] which results in decreased transport of benzoylaconine|[cyclosporine results in decreased activity of ABCB1 protein] which results in decreased transport of benzoylmesaconine|[cyclosporine results in decreased activity of ABCB1 protein] which results in decreased transport of mesaconitine|[cyclosporine results in decreased activity of ABCB1 protein] which results in decreased transport of benzoylhypaconine|[cyclosporine results in decreased activity of ABCB1 protein] which results in decreased transport of hypaconitine

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP082880

ABCB1

Homo sapiens (human)

[cyclosporine results in decreased activity of ABCB1 protein] which results in increased susceptibility to paclitaxel

https://ctdbase.org/detail.go?type=gene&acc=5243