Molecular Targets : Dataset Browser

BIMP_ID	Target Name	Gene	Organism	Action	Source URL
BIMP082095	ABCB1	ABCB1	Homo sapiens (human)	[ABCB1 protein results in decreased susceptibility to doxorubicin] inhibits the reaction [quercetin results in increased cleavage of PARP1 protein]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP082095	ABCB1	ABCB1	Homo sapiens (human)	ABCB1 protein results in increased transport of quercetin	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP082095	ABCB1	ABCB1	Homo sapiens (human)	[quercetin co-treated with doxorubicin] results in decreased expression of ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP082095	ABCB1	ABCB1	Homo sapiens (human)	Quercetin inhibits the reaction [[ABCB1 protein results in decreased susceptibility to doxorubicin] promotes the reaction [tetradecanoylphorbol acetate results in increased expression of ABCB1 mrna]]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP082095	ABCB1	ABCB1	Homo sapiens (human)	Quercetin inhibits the reaction [doxorubicin results in increased expression of ABCB1 mrna]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP082095	ABCB1	ABCB1	Homo sapiens (human)	Quercetin results in decreased expression of ABCB1	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP082095	ABCB1	ABCB1	Homo sapiens (human)	Quercetin results in decreased expression of ABCB1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP082095	ABCB1	ABCB1	Homo sapiens (human)	Quercetin results in decreased expression of ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP082095	ABCB1	ABCB1	Homo sapiens (human)	Quercetin results in increased expression of ABCB1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP082095	ABCB1	ABCB1	Homo sapiens (human)	Quercetin results in increased expression of ABCB1 protein\|vdr promotes the reaction [quercetin results in increased expression of ABCB1 mrna]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP082126	ABCB1	ABCB1	Homo sapiens (human)	Calcitriol results in increased expression of ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP082126	ABCB1	ABCB1	Homo sapiens (human)	VDR protein promotes the reaction [calcitriol results in increased expression of ABCB1 mrna]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP082126	ABCB1	ABCB1	Homo sapiens (human)	[calcitriol co-treated with curcumin] inhibits the reaction [paclitaxel results in increased expression of ABCB1 protein]\|curcumin inhibits the reaction [[calcitriol co-treated with paclitaxel] results in increased expression of ABCB1 protein]\|[curcumin co-treated with calcitriol] inhibits the reaction [paclitaxel results in increased expression of ABCB1 protein]\|curcumin inhibits the reaction [[calcitriol co-treated with paclitaxel] results in increased expression of ABCB1 mrna]\|[calcitriol co-treated with paclitaxel] results in increased expression of ABCB1 protein\|calcitriol inhibits the reaction [[curcumin co-treated with paclitaxel] results in increased expression of ABCB1 protein]\|[curcumin co-treated with calcitriol] inhibits the reaction [paclitaxel results in increased expression of ABCB1 mrna]\|calcitriol inhibits the reaction [paclitaxel results in increased expression of ABCB1 protein]\|calcitriol promotes the reaction [curcumin inhibits the reaction [paclitaxel results in increased expression of ABCB1 protein]]\|[calcitriol co-treated with paclitaxel] results in increased expression of ABCB1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP082126	ABCB1	ABCB1	Homo sapiens (human)	Calcitriol results in decreased activity of ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP082126	ABCB1	ABCB1	Homo sapiens (human)	Calcitriol results in increased expression of ABCB1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP082122	ABCB1	ABCB1	Homo sapiens (human)	Luteolin inhibits the reaction [ABCB1 protein results in decreased uptake of daunorubicin]\|luteolin results in increased activity of ABCB1 protein\|luteolin results in decreased expression of ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP082126	ABCB1	ABCB1	Homo sapiens (human)	[dihydroxy-vitamin D3 results in decreased susceptibility to particulate matter] which results in decreased expression of ABCB1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP082212	ABCB1	ABCB1	Homo sapiens (human)	Rutin promotes the reaction [elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of rhodamine 123]]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP082128	ABCB1	ABCB1	Homo sapiens (human)	Quercitrin promotes the reaction [elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of rhodamine 123]]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP080548	ABCB1	ABCB1	Homo sapiens (human)		https://www.dgidb.org/genes/hgnc:40
BIMP081473	ABCB1	ABCB1	Homo sapiens (human)	4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [daunorubicin results in increased expression of ABCB1 protein]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP080586	ABCB1	ABCB1	Cyprinus carpio (common carp)	Propranolol results in increased expression of ABCB1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP080586	ABCB1	ABCB1	Homo sapiens (human)	Propranolol inhibits the reaction [ABCB1 protein results in increased transport of digoxin]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP080586	ABCB1	ABCB1	Homo sapiens (human)	Propranolol results in increased expression of ABCB1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP082106	ABCB1	ABCB1	Homo sapiens (human)	Biochanin A inhibits the reaction [elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of rhodamine 123]]\|biochanin A inhibits the reaction [ABCB1 protein results in decreased uptake of daunorubicin]\|biochanin A promotes the reaction [elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of daunorubicin]]\|biochanin A promotes the reaction [ABCB1 protein results in decreased uptake of rhodamine 123]	https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP082095

ABCB1

Homo sapiens (human)

[ABCB1 protein results in decreased susceptibility to doxorubicin] inhibits the reaction [quercetin results in increased cleavage of PARP1 protein]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP082095

ABCB1

Homo sapiens (human)

ABCB1 protein results in increased transport of quercetin

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP082095

ABCB1

Homo sapiens (human)

[quercetin co-treated with doxorubicin] results in decreased expression of ABCB1 protein

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP082095

ABCB1

Homo sapiens (human)

Quercetin inhibits the reaction [[ABCB1 protein results in decreased susceptibility to doxorubicin] promotes the reaction [tetradecanoylphorbol acetate results in increased expression of ABCB1 mrna]]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP082095

ABCB1

Homo sapiens (human)

Quercetin inhibits the reaction [doxorubicin results in increased expression of ABCB1 mrna]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP082095

ABCB1

Homo sapiens (human)

Quercetin results in decreased expression of ABCB1

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP082095

ABCB1

Homo sapiens (human)

Quercetin results in decreased expression of ABCB1 mRNA

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP082095

ABCB1

Homo sapiens (human)

Quercetin results in decreased expression of ABCB1 protein

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP082095

ABCB1

Homo sapiens (human)

Quercetin results in increased expression of ABCB1 mRNA

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP082095

ABCB1

Homo sapiens (human)

Quercetin results in increased expression of ABCB1 protein|vdr promotes the reaction [quercetin results in increased expression of ABCB1 mrna]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP082126

ABCB1

Homo sapiens (human)

Calcitriol results in increased expression of ABCB1 protein

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP082126

ABCB1

Homo sapiens (human)

VDR protein promotes the reaction [calcitriol results in increased expression of ABCB1 mrna]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP082126

ABCB1

Homo sapiens (human)

[calcitriol co-treated with curcumin] inhibits the reaction [paclitaxel results in increased expression of ABCB1 protein]|curcumin inhibits the reaction [[calcitriol co-treated with paclitaxel] results in increased expression of ABCB1 protein]|[curcumin co-treated with calcitriol] inhibits the reaction [paclitaxel results in increased expression of ABCB1 protein]|curcumin inhibits the reaction [[calcitriol co-treated with paclitaxel] results in increased expression of ABCB1 mrna]|[calcitriol co-treated with paclitaxel] results in increased expression of ABCB1 protein|calcitriol inhibits the reaction [[curcumin co-treated with paclitaxel] results in increased expression of ABCB1 protein]|[curcumin co-treated with calcitriol] inhibits the reaction [paclitaxel results in increased expression of ABCB1 mrna]|calcitriol inhibits the reaction [paclitaxel results in increased expression of ABCB1 protein]|calcitriol promotes the reaction [curcumin inhibits the reaction [paclitaxel results in increased expression of ABCB1 protein]]|[calcitriol co-treated with paclitaxel] results in increased expression of ABCB1 mRNA

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP082126

ABCB1

Homo sapiens (human)

Calcitriol results in decreased activity of ABCB1 protein

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP082126

ABCB1

Homo sapiens (human)

Calcitriol results in increased expression of ABCB1 mRNA

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP082122

ABCB1

Homo sapiens (human)

Luteolin inhibits the reaction [ABCB1 protein results in decreased uptake of daunorubicin]|luteolin results in increased activity of ABCB1 protein|luteolin results in decreased expression of ABCB1 protein

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP082126

ABCB1

Homo sapiens (human)

[dihydroxy-vitamin D3 results in decreased susceptibility to particulate matter] which results in decreased expression of ABCB1 mRNA

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP082212

ABCB1

Homo sapiens (human)

Rutin promotes the reaction [elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of rhodamine 123]]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP082128

ABCB1

Homo sapiens (human)

Quercitrin promotes the reaction [elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of rhodamine 123]]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP080548

ABCB1

Homo sapiens (human)

https://www.dgidb.org/genes/hgnc:40

BIMP081473

ABCB1

Homo sapiens (human)

4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [daunorubicin results in increased expression of ABCB1 protein]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP080586

ABCB1

Cyprinus carpio (common carp)

Propranolol results in increased expression of ABCB1 mRNA

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP080586

ABCB1

Homo sapiens (human)

Propranolol inhibits the reaction [ABCB1 protein results in increased transport of digoxin]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP080586

ABCB1

Homo sapiens (human)

Propranolol results in increased expression of ABCB1 mRNA

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP082106

ABCB1

Homo sapiens (human)

Biochanin A inhibits the reaction [elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of rhodamine 123]]|biochanin A inhibits the reaction [ABCB1 protein results in decreased uptake of daunorubicin]|biochanin A promotes the reaction [elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of daunorubicin]]|biochanin A promotes the reaction [ABCB1 protein results in decreased uptake of rhodamine 123]

https://ctdbase.org/detail.go?type=gene&acc=5243