Molecular Targets : Dataset Browser

BIMP_ID	Target Name	Gene	Organism	Action	Source URL
BIMP090533	ABCB1	ABCB1	Homo sapiens (human)	ABCB1 results in decreased susceptibility to prednisolone	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP090534	ABCB1	ABCB1	Homo sapiens (human)	Estriol results in increased expression of ABCB1 protein\|abcb1 protein results in increased export of estriol\|estriol results in increased expression of ABCB1 mrna\|elacridar inhibits the reaction [ABCB1 protein results in increased export of estriol]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP091061	ABCB1	ABCB1	Homo sapiens (human)	Elacridar results in decreased export of [ABCB1 protein results in increased transport of ethinyl estradiol]\|abcb1 protein results in increased export of ethinyl estradiol\|ethinyl estradiol results in increased expression of ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP091061	ABCB1	ABCB1	Homo sapiens (human)	Ethinyl estradiol results in increased expression of ABCB1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP091061	ABCB1	ABCB1	Homo sapiens (human)	Ethinyl estradiol results in increased expression of and results in increased activity of ABCB1 protein\|fulvestrant inhibits the reaction [ethinyl estradiol results in increased expression of ABCB1 protein]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP091430	ABCB1	ABCB1	Rattus norvegicus (Norway rat)	Dimethylnitrosamine results in increased expression of ABCB1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP091270	ABCB1	ABCB1	Homo sapiens (human)	ABCB1 gene affects the reaction [CYP2C19 gene affects the susceptibility to clopidogrel]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP091270	ABCB1	ABCB1	Homo sapiens (human)	ABCB1 gene affects the susceptibility to clopidogrel\|clopidogrel results in decreased expression of ABCB1 protein\|abcb1 protein results in increased secretion of clopidogrel\|clopidogrel results in decreased expression of ABCB1 mrna\|clopidogrel results in decreased activity of ABCB1 protein\|abcb1 protein results in decreased uptake of clopidogrel	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP091270	ABCB1	ABCB1	Homo sapiens (human)	ABCB1 gene polymorphism affects the susceptibility to clopidogrel	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP091270	ABCB1	ABCB1	Homo sapiens (human)	ABCB1 gene SNP affects the susceptibility to clopidogrel	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP091270	ABCB1	ABCB1	Rattus norvegicus (Norway rat)	[aspirin results in increased expression of ABCB1 protein] which results in decreased uptake of clopidogrel	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP091285	ABCB1	ABCB1	Homo sapiens (human)	Gemcitabine results in decreased expression of ABCB1 mrna\|gemcitabine results in decreased expression of ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP091300	ABCB1	ABCB1	Homo sapiens (human)	ABCB1 exon SNP affects the susceptibility to and affects the metabolism of irinotecan	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP091300	ABCB1	ABCB1	Homo sapiens (human)	ABCB1 gene polymorphism affects the susceptibility to irinotecan	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP091300	ABCB1	ABCB1	Homo sapiens (human)	ABCB1 protein affects the export of irinotecan	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP091300	ABCB1	ABCB1	Homo sapiens (human)	ABCB1 protein results in decreased susceptibility to irinotecan	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP091300	ABCB1	ABCB1	Homo sapiens (human)	ABCB1 protein results in increased export of irinotecan	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP080495	ABCB1	ABCB1	Homo sapiens (human)	Pioglitazone results in increased expression of ABCB1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP080430	ABCB1	ABCB1	Bos taurus (cattle)	Colforsin results in increased expression of ABCB1 mrna\|[rifampin co-treated with colforsin] results in increased expression of ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP080430	ABCB1	ABCB1	Homo sapiens (human)	Colforsin results in increased expression of ABCB1 mrna\|n-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [colforsin results in increased expression of ABCB1 mrna]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP079668	ABCB1	ABCB1	Homo sapiens (human)	Benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [CERS6 protein affects the expression of ABCB1 protein]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP079733	ABCB1	ABCB1	Homo sapiens (human)	ABCB1 protein results in increased export of palmidrol	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP082095	ABCB1	ABCB1	Canis lupus familiaris (dog)	Quercetin inhibits the reaction [ABCB1 protein results in increased secretion of ritonavir]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP082095	ABCB1	ABCB1	Homo sapiens (human)	Verapamil promotes the reaction [quercetin results in increased activity of ABCB1 protein]\|quercetin inhibits the reaction [ABCB1 protein results in decreased uptake of daunorubicin]\|quercetin inhibits the reaction [ABCB1 protein results in decreased uptake of rhodamine 123]\|genistein promotes the reaction [quercetin results in increased activity of ABCB1 protein]\|morin promotes the reaction [quercetin results in increased activity of ABCB1 protein]\|quercetin promotes the reaction [elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of rhodamine 123]]\|quercetin results in increased activity of ABCB1 protein\|3-methylquercetin promotes the reaction [quercetin results in increased activity of ABCB1 protein]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP082095	ABCB1	ABCB1	Homo sapiens (human)	Verapamil inhibits the reaction [ABCB1 protein results in decreased abundance of quercetin]\|abcb1 protein results in decreased abundance of quercetin	https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP090533

ABCB1

Homo sapiens (human)

ABCB1 results in decreased susceptibility to prednisolone