Molecular Targets : Dataset Browser

BIMP_ID	Target Name	Gene	Organism	Action	Source URL
BIMP091713	ABCB1	ABCB1	Homo sapiens (human)	Cytarabine results in increased expression of ABCB1	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP094101	ABCB1	ABCB1	Drosophila melanogaster (fruit fly)	Pyrrolidine dithiocarbamic acid inhibits the reaction [avermectin results in increased expression of ABCB1 protein]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP094101	ABCB1	ABCB1	Oryctolagus cuniculus (rabbit)	Pyrrolidine dithiocarbamic acid results in decreased expression of ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP094101	ABCB1	ABCB1	Rattus norvegicus (Norway rat)	Pyrrolidine dithiocarbamic acid inhibits the reaction [cadmium chloride results in increased expression of ABCB1]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP092468	ABCB1	ABCB1	Homo sapiens (human)	Isosafrole results in increased expression of ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP092493	ABCB1	ABCB1	Homo sapiens (human)	Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [piperine results in increased expression of ABCB1 protein]]\|nr1i2 protein promotes the reaction [piperine results in increased expression of ABCB1 protein]\|nr1i2 protein promotes the reaction [piperine results in increased expression of ABCB1 mrna]\|ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [piperine results in increased expression of ABCB1 mrna]]\|piperine results in increased expression of ABCB1 protein\|piperine results in increased expression of ABCB1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP092493	ABCB1	ABCB1	Homo sapiens (human)	Piperine analog results in decreased expression of ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP092559	ABCB1	ABCB1	Homo sapiens (human)	Antofine results in decreased expression of ABCB1 mrna\|antofine results in decreased expression of ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP092626	ABCB1	ABCB1	Homo sapiens (human)		https://www.dgidb.org/genes/hgnc:40
BIMP093248	ABCB1	ABCB1	Homo sapiens (human)	Germacrone inhibits the reaction [doxorubicin results in increased expression of ABCB1 mrna]\|germacrone inhibits the reaction [doxorubicin results in increased expression of ABCB1 protein]\|abcb1 protein inhibits the reaction [germacrone results in increased susceptibility to doxorubicin]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP093349	ABCB1	ABCB1	Homo sapiens (human)	Plastochromanol 8 results in increased expression of ABCB1	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP093508	ABCB1	ABCB1	Homo sapiens (human)		https://www.dgidb.org/genes/hgnc:40
BIMP093723	ABCB1	ABCB1	Homo sapiens (human)	Mulberroside A inhibits the reaction [[NR1I2 protein results in increased susceptibility to rifampin] which results in increased expression of ABCB1 mrna]\|mulberroside A inhibits the reaction [[NR1I2 protein results in increased susceptibility to rifampin] which results in increased expression of ABCB1 protein]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP093723	ABCB1	ABCB1	Homo sapiens (human)	Mulberroside A results in decreased expression of ABCB1 mrna\|mulberroside A results in decreased expression of and results in decreased activity of ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP093917	ABCB1	ABCB1	Homo sapiens (human)	Dehydroandrographolide inhibits the reaction [ABCB1 protein results in increased transport of digoxin]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP094060	ABCB1	ABCB1	Homo sapiens (human)	Epigallocatechin gallate results in decreased expression of ABCB1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP094060	ABCB1	ABCB1	Homo sapiens (human)	Epigallocatechin gallate results in decreased expression of ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP094027	ABCB1	ABCB1	Homo sapiens (human)	Ginkgo biloba extract results in increased expression of ABCB1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP100631	ABCB1	ABCB1	Homo sapiens (human)	Rosiglitazone results in increased expression of ABCB1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP098940	ABCB1	ABCB1	Homo sapiens (human)	Gamma-terpinene inhibits the reaction [ABCB1 protein results in increased uptake of digoxin]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP099736	ABCB1	ABCB1	Homo sapiens (human)	Glycerol affects the metabolism of and affects the localization of ABCB1 protein mutant form	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP100888	ABCB1	ABCB1	Oryctolagus cuniculus (rabbit)	Hydroquinone results in decreased expression of ABCB1 protein\|hydroquinone results in decreased expression of ABCB1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP101020	ABCB1	ABCB1	Homo sapiens (human)	Indole promotes the reaction [NR1I2 protein binds to ABCB1 promoter]\|indole results in increased expression of ABCB1 mrna\|nr1i2 protein promotes the reaction [indole results in increased expression of ABCB1 mrna]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP098224	ABCB1	ABCB1	Bos taurus (cattle)	Prochloraz results in increased expression of ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP098224	ABCB1	ABCB1	Oncorhynchus mykiss (rainbow trout)	Prochloraz results in decreased activity of ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP091713

ABCB1

Homo sapiens (human)

Cytarabine results in increased expression of ABCB1

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP094101

ABCB1

Drosophila melanogaster (fruit fly)

Pyrrolidine dithiocarbamic acid inhibits the reaction [avermectin results in increased expression of ABCB1 protein]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP094101

ABCB1

Oryctolagus cuniculus (rabbit)

Pyrrolidine dithiocarbamic acid results in decreased expression of ABCB1 protein

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP094101

ABCB1

Rattus norvegicus (Norway rat)

Pyrrolidine dithiocarbamic acid inhibits the reaction [cadmium chloride results in increased expression of ABCB1]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP092468

ABCB1

Homo sapiens (human)

Isosafrole results in increased expression of ABCB1 protein

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP092493

ABCB1

Homo sapiens (human)

Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [piperine results in increased expression of ABCB1 protein]]|nr1i2 protein promotes the reaction [piperine results in increased expression of ABCB1 protein]|nr1i2 protein promotes the reaction [piperine results in increased expression of ABCB1 mrna]|ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [piperine results in increased expression of ABCB1 mrna]]|piperine results in increased expression of ABCB1 protein|piperine results in increased expression of ABCB1 mRNA

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP092493

ABCB1

Homo sapiens (human)

Piperine analog results in decreased expression of ABCB1 protein

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP092559

ABCB1

Homo sapiens (human)

Antofine results in decreased expression of ABCB1 mrna|antofine results in decreased expression of ABCB1 protein

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP092626

ABCB1

Homo sapiens (human)

https://www.dgidb.org/genes/hgnc:40

BIMP093248

ABCB1

Homo sapiens (human)

Germacrone inhibits the reaction [doxorubicin results in increased expression of ABCB1 mrna]|germacrone inhibits the reaction [doxorubicin results in increased expression of ABCB1 protein]|abcb1 protein inhibits the reaction [germacrone results in increased susceptibility to doxorubicin]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP093349

ABCB1

Homo sapiens (human)

Plastochromanol 8 results in increased expression of ABCB1

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP093508

ABCB1

Homo sapiens (human)

https://www.dgidb.org/genes/hgnc:40

BIMP093723

ABCB1

Homo sapiens (human)

Mulberroside A inhibits the reaction [[NR1I2 protein results in increased susceptibility to rifampin] which results in increased expression of ABCB1 mrna]|mulberroside A inhibits the reaction [[NR1I2 protein results in increased susceptibility to rifampin] which results in increased expression of ABCB1 protein]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP093723

ABCB1

Homo sapiens (human)

Mulberroside A results in decreased expression of ABCB1 mrna|mulberroside A results in decreased expression of and results in decreased activity of ABCB1 protein

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP093917

ABCB1

Homo sapiens (human)

Dehydroandrographolide inhibits the reaction [ABCB1 protein results in increased transport of digoxin]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP094060

ABCB1

Homo sapiens (human)

Epigallocatechin gallate results in decreased expression of ABCB1 mRNA

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP094060

ABCB1

Homo sapiens (human)

Epigallocatechin gallate results in decreased expression of ABCB1 protein

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP094027

ABCB1

Homo sapiens (human)

Ginkgo biloba extract results in increased expression of ABCB1 mRNA

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP100631

ABCB1

Homo sapiens (human)

Rosiglitazone results in increased expression of ABCB1 mRNA

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP098940

ABCB1

Homo sapiens (human)

Gamma-terpinene inhibits the reaction [ABCB1 protein results in increased uptake of digoxin]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP099736

ABCB1

Homo sapiens (human)

Glycerol affects the metabolism of and affects the localization of ABCB1 protein mutant form

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP100888

ABCB1

Oryctolagus cuniculus (rabbit)

Hydroquinone results in decreased expression of ABCB1 protein|hydroquinone results in decreased expression of ABCB1 mRNA

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP101020

ABCB1

Homo sapiens (human)

Indole promotes the reaction [NR1I2 protein binds to ABCB1 promoter]|indole results in increased expression of ABCB1 mrna|nr1i2 protein promotes the reaction [indole results in increased expression of ABCB1 mrna]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP098224

ABCB1

Bos taurus (cattle)

Prochloraz results in increased expression of ABCB1 protein

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP098224

ABCB1

Oncorhynchus mykiss (rainbow trout)

Prochloraz results in decreased activity of ABCB1 protein

https://ctdbase.org/detail.go?type=gene&acc=5243