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SCFBio, IIT Delhi Hauz Khas, New Delhi

Molecular Targets

Interactions between compounds and specific gene/protein targets.

Total Rows 750,454
Pages 30,019
BIMP_ID Target Name Gene Organism Action Source URL
ABCB1
Dreissena polymorpha
[musk ketone results in decreased activity of ABCB1 protein] which results in decreased export of calcein am|musk ketone results in decreased activity of ABCB1 protein
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Cricetulus griseus (Chinese hamster)
Sesquiterpenes analog binds to and affects the activity of ABCB1 protein|sesquiterpenes analog inhibits the reaction [ABCB1 protein affects the transport of colchicine]|sesquiterpenes analog inhibits the reaction [ABCB1 protein affects the transport of tetramethylrosamine]|sesquiterpenes analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to vinblastine]|sesquiterpenes analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to daunorubicin]
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Homo sapiens (human)
3,3',4,5'-tetrahydroxystilbene results in increased expression of ABCB1 protein
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Homo sapiens (human)
ABCB1 gene polymorphism affects the susceptibility to [methotrexate co-treated with methylprednisolone]|abcb1 protein results in increased susceptibility to [methotrexate co-treated with methylprednisolone]
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Homo sapiens (human)
Valspodar inhibits the reaction [ABCB1 protein results in increased secretion of methylprednisolone]|elacridar inhibits the reaction [ABCB1 protein results in increased secretion of methylprednisolone]|abcb1 protein results in increased secretion of methylprednisolone
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Homo sapiens (human)
Methylprednisolone results in increased expression of ABCB1 mRNA
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Homo sapiens (human)
Methylprednisolone results in increased expression of ABCB1 protein
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Homo sapiens (human)
https://www.dgidb.org/genes/hgnc:40
ABCB1
Homo sapiens (human)
https://www.dgidb.org/genes/hgnc:40
ABCB1
Cricetulus griseus (Chinese hamster)
Sesquiterpenes analog inhibits the reaction [ABCB1 protein affects the transport of colchicine]
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Homo sapiens (human)
ABCB1 protein affects the transport of colchicine
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Homo sapiens (human)
ABCB1 protein results in decreased susceptibility to colchicine
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Homo sapiens (human)
ABCB1 protein results in increased export of colchicine
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Homo sapiens (human)
Colchicine inhibits the reaction [verapamil analog results in increased activity of ABCB1 protein mutant form]
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Homo sapiens (human)
Colchicine results in increased expression of ABCB1
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Homo sapiens (human)
Colchicine results in increased expression of ABCB1 mRNA
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Homo sapiens (human)
[MGMT protein co-treated with ABCB1 protein] results in decreased susceptibility to colchicine
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Ovis aries (sheep)
ABCB1 results in decreased susceptibility to colchicine
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Homo sapiens (human)
Chloroform results in increased expression of ABCB1 mRNA
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Rattus norvegicus (Norway rat)
Chloroform results in increased expression of ABCB1 mRNA
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Homo sapiens (human)
ABCB1 protein results in increased transport of strophanthidin
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Homo sapiens (human)
Cycloheximide results in increased expression of ABCB1 mrna|cycloheximide promotes the reaction [reserpine results in increased expression of ABCB1 mrna]
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Rattus norvegicus (Norway rat)
Cycloheximide inhibits the reaction [vehicle emissions results in increased expression of and results in increased activity of ABCB1 protein]|cycloheximide inhibits the reaction [[particulate matter results in increased expression of and results in increased activity of ABCB1 protein] which results in increased uptake of (N-5-(4-nitrobenzofurazan-7-yl)lysyl(8))cyclosporine]|cycloheximide inhibits the reaction [[vehicle emissions results in increased expression of and results in increased activity of ABCB1 protein] which results in increased uptake of (N-5-(4-nitrobenzofurazan-7-yl)lysyl(8))cyclosporine]|cycloheximide inhibits the reaction [particulate matter results in increased expression of and results in increased activity of ABCB1 protein]
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Rattus norvegicus (Norway rat)
Mannitol inhibits the reaction [vitamin A results in decreased expression of ABCB1 mrna]
https://ctdbase.org/detail.go?type=gene&acc=5243
ABCB1
Homo sapiens (human)
ABCB1 protein affects the susceptibility to cytarabine
https://ctdbase.org/detail.go?type=gene&acc=5243
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