Molecular Targets : Dataset Browser

BIMP_ID	Target Name	Gene	Organism	Action	Source URL
BIMP105027	ABCB1	ABCB1	Homo sapiens (human)	Curcumin results in decreased expression of ABCB1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP105027	ABCB1	ABCB1	Homo sapiens (human)	Curcumin results in decreased expression of and results in decreased activity of ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP105027	ABCB1	ABCB1	Homo sapiens (human)	[sulfinosine co-treated with curcumin] results in decreased expression of ABCB1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP105027	ABCB1	ABCB1	Mus musculus (house mouse)	Curcumin inhibits the reaction [trinitrobenzenesulfonic acid results in decreased expression of ABCB1 mrna]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP105027	ABCB1	ABCB1	Homo sapiens (human)		https://www.dgidb.org/genes/hgnc:40
BIMP104621	ABCB1	ABCB1	Homo sapiens (human)	5-methoxyflavone inhibits the reaction [ABCB1 protein results in decreased uptake of daunorubicin]\|5-methoxyflavone inhibits the reaction [ABCB1 protein results in decreased uptake of rhodamine 123]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP104844	ABCB1	ABCB1	Homo sapiens (human)	Bufalin inhibits the reaction [ABCB1 protein results in increased transport of quinidinium]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP102873	ABCB1	ABCB1	Homo sapiens (human)	Cinchonine inhibits the reaction [ABCB1 protein results in decreased susceptibility to docetaxel]\|cinchonine analog results in decreased expression of ABCB1 protein\|cinchonine analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to paclitaxel]\|cinchonine analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to docetaxel]\|cinchonine inhibits the reaction [ABCB1 protein results in decreased susceptibility to paclitaxel]\|cinchonine results in decreased expression of ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP102821	ABCB1	ABCB1	Rattus norvegicus (Norway rat)	Melatonin inhibits the reaction [methamphetamine results in decreased expression of ABCB1 protein]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP105492	ABCB1	ABCB1	Homo sapiens (human)	Parathion inhibits the reaction [ABCB1 protein results in increased export of doxorubicin]\|abcb1 protein results in decreased export of parathion\|parathion binds to ABCB1 protein	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP105476	ABCB1	ABCB1	Homo sapiens (human)	Lithocholic acid results in increased expression of ABCB1 mrna\|vdr protein promotes the reaction [lithocholic acid results in increased expression of ABCB1 mrna]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP105524	ABCB1	ABCB1	Homo sapiens (human)	Ginsenoside F2 analog inhibits the reaction [ABCB1 protein results in increased transport of digoxin]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP105677	ABCB1	ABCB1	Homo sapiens (human)		https://www.dgidb.org/genes/hgnc:40
BIMP102763	ABCB1	ABCB1	Homo sapiens (human)	5,7-dimethoxyflavone inhibits the reaction [ABCB1 protein results in decreased uptake of rhodamine 123]\|5,7-dimethoxyflavone inhibits the reaction [elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of rhodamine 123]]\|5,7-dimethoxyflavone inhibits the reaction [ABCB1 protein results in decreased uptake of daunorubicin]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP101323	ABCB1	ABCB1	Homo sapiens (human)		https://www.dgidb.org/genes/hgnc:40
BIMP101570	ABCB1	ABCB1	Homo sapiens (human)	Pyrazolanthrone inhibits the reaction [oxygen deficiency results in increased expression of ABCB1 mrna]\|pyrazolanthrone inhibits the reaction [MAP3K1 protein results in increased expression of ABCB1 mrna]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP101570	ABCB1	ABCB1	Rattus norvegicus (Norway rat)	Pyrazolanthrone inhibits the reaction [particulate matter results in increased expression of and results in increased activity of ABCB1 protein]\|pyrazolanthrone inhibits the reaction [vehicle emissions results in increased expression of and results in increased activity of ABCB1 protein]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP095241	ABCB1	ABCB1	Homo sapiens (human)	Ketoconazole inhibits the reaction [ethanol results in increased expression of ABCB1 mrna]\|ethanol results in increased expression of ABCB1 mrna\|glutathione inhibits the reaction [ethanol results in increased expression of ABCB1 mrna]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP095241	ABCB1	ABCB1	Rattus norvegicus (Norway rat)	Ethanol results in increased expression of ABCB1 mrna\|[aflatoxin B1 co-treated with ethanol] results in increased expression of ABCB1 mrna\|sildenafil citrate inhibits the reaction [[aflatoxin B1 co-treated with ethanol] results in increased expression of ABCB1 mrna]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP094583	ABCB1	ABCB1	Homo sapiens (human)	Tangeretin results in increased activity of ABCB1 protein\|verapamil inhibits the reaction [tangeretin results in increased activity of ABCB1 protein]\|tangeretin inhibits the reaction [elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of rhodamine 123]]\|tangeretin results in decreased expression of ABCB1 protein\|tangeretin inhibits the reaction [ABCB1 protein results in decreased uptake of rhodamine 123]\|tangeretin inhibits the reaction [ABCB1 protein results in decreased uptake of daunorubicin]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP094583	ABCB1	ABCB1	Homo sapiens (human)	Tangeretin results in decreased activity of ABCB1 protein\|tangeretin inhibits the reaction [ABCB1 protein results in increased transport of digoxin]	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP094583	ABCB1	ABCB1	Homo sapiens (human)		https://www.dgidb.org/genes/hgnc:40
BIMP094567	ABCB1	ABCB1	Homo sapiens (human)		https://www.dgidb.org/genes/hgnc:40
BIMP094567	ABCB1	ABCB1	Homo sapiens (human)	Dimethyl sulfoxide affects the expression of ABCB1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=5243
BIMP094598	ABCB1	ABCB1	Homo sapiens (human)	5-hydroxyflavone inhibits the reaction [elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of daunorubicin]]\|5-hydroxyflavone inhibits the reaction [ABCB1 protein results in decreased uptake of rhodamine 123]	https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP105027

ABCB1

Homo sapiens (human)

Curcumin results in decreased expression of ABCB1 mRNA

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP105027

ABCB1

Homo sapiens (human)

Curcumin results in decreased expression of and results in decreased activity of ABCB1 protein

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP105027

ABCB1

Homo sapiens (human)

[sulfinosine co-treated with curcumin] results in decreased expression of ABCB1 mRNA

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP105027

ABCB1

Mus musculus (house mouse)

Curcumin inhibits the reaction [trinitrobenzenesulfonic acid results in decreased expression of ABCB1 mrna]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP105027

ABCB1

Homo sapiens (human)

https://www.dgidb.org/genes/hgnc:40

BIMP104621

ABCB1

Homo sapiens (human)

5-methoxyflavone inhibits the reaction [ABCB1 protein results in decreased uptake of daunorubicin]|5-methoxyflavone inhibits the reaction [ABCB1 protein results in decreased uptake of rhodamine 123]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP104844

ABCB1

Homo sapiens (human)

Bufalin inhibits the reaction [ABCB1 protein results in increased transport of quinidinium]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP102873

ABCB1

Homo sapiens (human)

Cinchonine inhibits the reaction [ABCB1 protein results in decreased susceptibility to docetaxel]|cinchonine analog results in decreased expression of ABCB1 protein|cinchonine analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to paclitaxel]|cinchonine analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to docetaxel]|cinchonine inhibits the reaction [ABCB1 protein results in decreased susceptibility to paclitaxel]|cinchonine results in decreased expression of ABCB1 protein

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP102821

ABCB1

Rattus norvegicus (Norway rat)

Melatonin inhibits the reaction [methamphetamine results in decreased expression of ABCB1 protein]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP105492

ABCB1

Homo sapiens (human)

Parathion inhibits the reaction [ABCB1 protein results in increased export of doxorubicin]|abcb1 protein results in decreased export of parathion|parathion binds to ABCB1 protein

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP105476

ABCB1

Homo sapiens (human)

Lithocholic acid results in increased expression of ABCB1 mrna|vdr protein promotes the reaction [lithocholic acid results in increased expression of ABCB1 mrna]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP105524

ABCB1

Homo sapiens (human)

Ginsenoside F2 analog inhibits the reaction [ABCB1 protein results in increased transport of digoxin]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP105677

ABCB1

Homo sapiens (human)

https://www.dgidb.org/genes/hgnc:40

BIMP102763

ABCB1

Homo sapiens (human)

5,7-dimethoxyflavone inhibits the reaction [ABCB1 protein results in decreased uptake of rhodamine 123]|5,7-dimethoxyflavone inhibits the reaction [elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of rhodamine 123]]|5,7-dimethoxyflavone inhibits the reaction [ABCB1 protein results in decreased uptake of daunorubicin]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP101323

ABCB1

Homo sapiens (human)

https://www.dgidb.org/genes/hgnc:40

BIMP101570

ABCB1

Homo sapiens (human)

Pyrazolanthrone inhibits the reaction [oxygen deficiency results in increased expression of ABCB1 mrna]|pyrazolanthrone inhibits the reaction [MAP3K1 protein results in increased expression of ABCB1 mrna]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP101570

ABCB1

Rattus norvegicus (Norway rat)

Pyrazolanthrone inhibits the reaction [particulate matter results in increased expression of and results in increased activity of ABCB1 protein]|pyrazolanthrone inhibits the reaction [vehicle emissions results in increased expression of and results in increased activity of ABCB1 protein]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP095241

ABCB1

Homo sapiens (human)

Ketoconazole inhibits the reaction [ethanol results in increased expression of ABCB1 mrna]|ethanol results in increased expression of ABCB1 mrna|glutathione inhibits the reaction [ethanol results in increased expression of ABCB1 mrna]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP095241

ABCB1

Rattus norvegicus (Norway rat)

Ethanol results in increased expression of ABCB1 mrna|[aflatoxin B1 co-treated with ethanol] results in increased expression of ABCB1 mrna|sildenafil citrate inhibits the reaction [[aflatoxin B1 co-treated with ethanol] results in increased expression of ABCB1 mrna]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP094583

ABCB1

Homo sapiens (human)

Tangeretin results in increased activity of ABCB1 protein|verapamil inhibits the reaction [tangeretin results in increased activity of ABCB1 protein]|tangeretin inhibits the reaction [elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of rhodamine 123]]|tangeretin results in decreased expression of ABCB1 protein|tangeretin inhibits the reaction [ABCB1 protein results in decreased uptake of rhodamine 123]|tangeretin inhibits the reaction [ABCB1 protein results in decreased uptake of daunorubicin]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP094583

ABCB1

Homo sapiens (human)

Tangeretin results in decreased activity of ABCB1 protein|tangeretin inhibits the reaction [ABCB1 protein results in increased transport of digoxin]

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP094583

ABCB1

Homo sapiens (human)

https://www.dgidb.org/genes/hgnc:40

BIMP094567

ABCB1

Homo sapiens (human)

https://www.dgidb.org/genes/hgnc:40

BIMP094567

ABCB1

Homo sapiens (human)

Dimethyl sulfoxide affects the expression of ABCB1 mRNA

https://ctdbase.org/detail.go?type=gene&acc=5243

BIMP094598

ABCB1

Homo sapiens (human)

5-hydroxyflavone inhibits the reaction [elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of daunorubicin]]|5-hydroxyflavone inhibits the reaction [ABCB1 protein results in decreased uptake of rhodamine 123]

https://ctdbase.org/detail.go?type=gene&acc=5243