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Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
ABCA9
|
Mus musculus (house mouse)
|
[NR1H4 protein mutant form inhibits the reaction [cholic acid results in increased phosphorylation of NR1H4 protein]] which results in decreased expression of ABCA9 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10350
|
||
|
ABCA9
|
Homo sapiens (human)
|
Bisphenol A results in increased methylation of ABCA9 gene
|
https://ctdbase.org/detail.go?type=gene&acc=10350
|
||
|
ABCA9
|
Mus musculus (house mouse)
|
Bisphenol A results in increased expression of ABCA9 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10350
|
||
|
ABCA9
|
Ovis aries (sheep)
|
[[biotin co-treated with pantothenic acid co-treated with INS protein co-treated with dexamethasone co-treated with 1-methyl-3-isobutylxanthine co-treated with rosiglitazone] results in increased susceptibility to bisphenol A] which results in increased expression of ABCA9 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10350
|
||
|
ABCA9
|
Rattus norvegicus (Norway rat)
|
Bisphenol A affects the expression of ABCA9 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10350
|
||
|
ABCA9
|
Rattus norvegicus (Norway rat)
|
Bisphenol A results in decreased expression of ABCA9 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10350
|
||
|
ABCA9
|
Ovis aries (sheep)
|
[[biotin co-treated with pantothenic acid co-treated with INS protein co-treated with dexamethasone co-treated with 1-methyl-3-isobutylxanthine co-treated with rosiglitazone] results in increased susceptibility to bisphenol A] which results in increased expression of ABCA9 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10350
|
||
|
ABCA9
|
Mus musculus (house mouse)
|
Ethanol affects the expression of ABCA9 mrna|ethanol results in increased expression of ABCA9 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10350
|
||
|
ABCA9
|
Ovis aries (sheep)
|
[[biotin co-treated with pantothenic acid co-treated with INS protein co-treated with dexamethasone co-treated with 1-methyl-3-isobutylxanthine co-treated with rosiglitazone] results in increased susceptibility to bisphenol A] which results in increased expression of ABCA9 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10350
|
||
|
ABCB1
|
Homo sapiens (human)
|
ABCB1 promoter SNP affects the reaction [bisphenol A results in increased expression of ABCB1 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
Bisphenol A affects the expression of ABCB1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
Bisphenol A results in increased expression of ABCB1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
Bisphenol A results in increased methylation of ABCB1 gene
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Mytilus galloprovincialis (Mediterranean mussel)
|
Bisphenol A results in increased expression of ABCB1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Paracentrotus lividus (common urchin)
|
Bisphenol A results in increased expression of ABCB1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Rattus norvegicus (Norway rat)
|
Bisphenol A results in decreased expression of ABCB1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
Diethylhexyl phthalate results in increased expression of ABCB1 mrna|diethylhexyl phthalate promotes the reaction [NR1I2 protein results in increased expression of ABCB1 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
Naphthalene results in decreased activity of ABCB1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
Chrysene results in increased expression of ABCB1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
Benzo(e)pyrene results in increased expression of ABCB1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
ABCB1 affects the susceptibility to curcumin
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
ABCB1 protein results in decreased susceptibility to curcumin
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
Curcumin inhibits the reaction [paclitaxel results in increased expression of ABCB1 protein]|curcumin inhibits the reaction [[calcitriol co-treated with paclitaxel] results in increased expression of ABCB1 protein]|[curcumin co-treated with calcitriol] inhibits the reaction [paclitaxel results in increased expression of ABCB1 protein]|curcumin inhibits the reaction [[calcitriol co-treated with paclitaxel] results in increased expression of ABCB1 mrna]|curcumin inhibits the reaction [paclitaxel results in increased expression of ABCB1 mrna]|calcitriol inhibits the reaction [[curcumin co-treated with paclitaxel] results in increased expression of ABCB1 protein]|[curcumin co-treated with calcitriol] inhibits the reaction [paclitaxel results in increased expression of ABCB1 mrna]|[calcitriol co-treated with curcumin] inhibits the reaction [paclitaxel results in increased expression of ABCB1 protein]|[curcumin co-treated with paclitaxel] results in increased expression of ABCB1 protein|calcitriol promotes the reaction [curcumin inhibits the reaction [paclitaxel results in increased expression of ABCB1 protein]]
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
Curcumin analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to paclitaxel]|curcumin inhibits the reaction [ABCB1 protein results in decreased susceptibility to vinblastine]|curcumin analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to vinblastine]|curcumin inhibits the reaction [ABCB1 protein results in decreased susceptibility to paclitaxel]|curcumin analog results in decreased expression of ABCB1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
||
|
ABCB1
|
Homo sapiens (human)
|
Curcumin inhibits the reaction [ABCB1 protein results in increased transport of digoxin]
|
https://ctdbase.org/detail.go?type=gene&acc=5243
|
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