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Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
ABCA1
|
Homo sapiens (human)
|
Estradiol results in decreased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Rattus norvegicus (Norway rat)
|
Estradiol results in increased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Homo sapiens (human)
|
[LG 100268 co-treated with [ascorbic acid co-treated with beta-glycerophosphoric acid co-treated with dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 mrna|diazepinylbenzoic acid inhibits the reaction [[LG 100268 co-treated with [ascorbic acid co-treated with beta-glycerophosphoric acid co-treated with dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 mrna]|[ascorbic acid co-treated with beta-glycerophosphoric acid co-treated with dexamethasone co-treated with INS protein] results in increased expression of ABCA1 mrna|[rosiglitazone co-treated with [ascorbic acid co-treated with beta-glycerophosphoric acid co-treated with dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 protein|[bexarotene co-treated with [ascorbic acid co-treated with beta-glycerophosphoric acid co-treated with dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 protein|diazepinylbenzoic acid inhibits the reaction [[tributyltin co-treated with [ascorbic acid co-treated with beta-glycerophosphoric acid co-treated with dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 mrna]|[tributyltin co-treated with [ascorbic acid co-treated with beta-glycerophosphoric acid co-treated with dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 protein|[tributyltin co-treated with [ascorbic acid co-treated with beta-glycerophosphoric acid co-treated with dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 mrna|[diazepinylbenzoic acid co-treated with [ascorbic acid co-treated with beta-glycerophosphoric acid co-treated with dexamethasone co-treated with INS protein]] results in decreased expression of ABCA1 mrna|[t0901317 co-treated with [ascorbic acid co-treated with beta-glycerophosphoric acid co-treated with dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Mus musculus (house mouse)
|
[dexamethasone co-treated with rosiglitazone co-treated with 1-methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Rattus norvegicus (Norway rat)
|
Dexamethasone results in increased expression of ABCA1 mrna|testosterone inhibits the reaction [dexamethasone results in increased expression of ABCA1 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Homo sapiens (human)
|
|
https://www.dgidb.org/genes/hgnc:29
|
||
|
ABCA1
|
Mus musculus (house mouse)
|
Cyclic AMP results in increased expression of ABCA1 protein|cyclic AMP results in increased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Mus musculus (house mouse)
|
[HCAR2 protein results in decreased abundance of cyclic AMP] which results in decreased expression of ABCA1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Homo sapiens (human)
|
Testosterone results in increased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Mus musculus (house mouse)
|
Testosterone results in decreased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Rattus norvegicus (Norway rat)
|
Testosterone inhibits the reaction [dexamethasone results in increased expression of ABCA1 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Mus musculus (house mouse)
|
Fenretinide results in increased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Mus musculus (house mouse)
|
Sulforaphane inhibits the reaction [fenamidone results in increased expression of ABCA1 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Rattus norvegicus (Norway rat)
|
Monocrotophos results in increased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Homo sapiens (human)
|
Licochalcone B results in decreased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Homo sapiens (human)
|
[genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Gallus gallus (chicken)
|
T-2 toxin results in decreased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Homo sapiens (human)
|
Cyclosporine results in decreased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Homo sapiens (human)
|
[sirolimus co-treated with cyclosporine] results in decreased expression of ABCA1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Mus musculus (house mouse)
|
Cyclosporine affects the reaction [capsaicin results in increased expression of ABCA1 protein]
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Mus musculus (house mouse)
|
Cyclosporine results in decreased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Rattus norvegicus (Norway rat)
|
Cyclosporine results in increased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Homo sapiens (human)
|
[vincristine results in decreased susceptibility to vincristine] which results in increased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Mus musculus (house mouse)
|
Trilinolein results in decreased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Homo sapiens (human)
|
Calcitriol results in increased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
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