Molecular Targets : Dataset Browser

BIMP_ID	Target Name	Gene	Organism	Action	Source URL
BIMP082124	ABCA1	ABCA1	Homo sapiens (human)	PLD2 protein inhibits the reaction [linoleic acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased export of cholesterol]]]\|linoleic acid results in increased degradation of ABCA1 protein\|1-butanol inhibits the reaction [linoleic acid inhibits the reaction [ABCA1 protein results in increased export of cholesterol]]\|linoleic acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of phospholipids]]\|triacsin C inhibits the reaction [linoleic acid inhibits the reaction [ABCA1 protein results in increased transport of phospholipids]]\|triacsin C inhibits the reaction [linoleic acid results in increased degradation of ABCA1 protein]\|linoleic acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of cholesterol]]\|linoleic acid inhibits the reaction [ABCA1 protein results in increased export of cholesterol]\|triacsin C inhibits the reaction [linoleic acid inhibits the reaction [ABCA1 protein results in increased transport of cholesterol]]\|linoleic acid results in increased phosphorylation of ABCA1 protein	https://ctdbase.org/detail.go?type=gene&acc=19
BIMP082124	ABCA1	ABCA1	Mus musculus (house mouse)	Linoleic acid analog results in decreased expression of ABCA1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=19
BIMP082124	ABCA1	ABCA1	Mus musculus (house mouse)	Linoleic acid inhibits the reaction [27-hydroxycholesterol results in increased expression of ABCA1 mrna]\|linoleic acid results in increased expression of ABCA1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=19
BIMP081972	ABCA1	ABCA1	Homo sapiens (human)	Propionaldehyde results in increased expression of ABCA1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=19
BIMP082212	ABCA1	ABCA1	Rattus norvegicus (Norway rat)	Rutin inhibits the reaction [carbon tetrachloride results in decreased expression of ABCA1 mrna]\|rutin inhibits the reaction [carbon tetrachloride results in decreased expression of ABCA1 protein]	https://ctdbase.org/detail.go?type=gene&acc=19
BIMP082209	ABCA1	ABCA1	Rattus norvegicus (Norway rat)	[cholecalciferol co-treated with dietary fats co-treated with particulate matter] results in increased expression of ABCA1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=19
BIMP080495	ABCA1	ABCA1	Homo sapiens (human)	Pioglitazone affects the expression of ABCA1 protein	https://ctdbase.org/detail.go?type=gene&acc=19
BIMP080495	ABCA1	ABCA1	Homo sapiens (human)	Pioglitazone results in increased expression of ABCA1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=19
BIMP080495	ABCA1	ABCA1	Homo sapiens (human)	Pioglitazone results in increased expression of ABCA1 mrna\|pioglitazone results in increased expression of ABCA1 protein	https://ctdbase.org/detail.go?type=gene&acc=19
BIMP080495	ABCA1	ABCA1	Sus scrofa (pig)	Pioglitazone results in increased expression of ABCA1 mrna\|pioglitazone affects the localization of ABCA1 protein	https://ctdbase.org/detail.go?type=gene&acc=19
BIMP080430	ABCA1	ABCA1	Homo sapiens (human)	Colforsin promotes the reaction [diethylhexyl phthalate results in decreased expression of ABCA1 mrna]	https://ctdbase.org/detail.go?type=gene&acc=19
BIMP082119	ABCA1	ABCA1	Mus musculus (house mouse)	Vitexin results in increased expression of ABCA1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=19
BIMP082095	ABCA1	ABCA1	Homo sapiens (human)	[quercetin co-treated with ascorbic acid] results in decreased expression of ABCA1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=19
BIMP082095	ABCA1	ABCA1	Homo sapiens (human)	Quercetin results in decreased expression of ABCA1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=19
BIMP082095	ABCA1	ABCA1	Homo sapiens (human)	Quercetin results in increased expression of ABCA1 mrna\|quercetin results in increased expression of ABCA1 protein	https://ctdbase.org/detail.go?type=gene&acc=19
BIMP082095	ABCA1	ABCA1	Mus musculus (house mouse)	Quercetin promotes the reaction [glutathione results in increased expression of ABCA1 mrna]\|glutathione promotes the reaction [quercetin results in increased expression of ABCA1 mrna]	https://ctdbase.org/detail.go?type=gene&acc=19
BIMP082095	ABCA1	ABCA1	Mus musculus (house mouse)	Quercetin results in increased expression of ABCA1 protein\|mapk14 protein promotes the reaction [quercetin promotes the reaction [SP1 protein binds to ABCA1 promoter]]\|mapk14 protein promotes the reaction [quercetin results in increased expression of ABCA1 protein]\|sb 203580 inhibits the reaction [quercetin results in increased expression of ABCA1 mrna]\|quercetin promotes the reaction [SP1 protein binds to ABCA1 promoter]\|mapk14 protein promotes the reaction [quercetin results in increased expression of ABCA1 mrna]\|sb 203580 inhibits the reaction [quercetin results in increased expression of ABCA1 protein]\|mapk14 protein promotes the reaction [quercetin promotes the reaction [NR1H3 protein binds to ABCA1 promoter]]	https://ctdbase.org/detail.go?type=gene&acc=19
BIMP082095	ABCA1	ABCA1	Mus musculus (house mouse)	Quercetin results in increased expression of ABCA1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=19
BIMP084816	ABCA10	ABCA10	Homo sapiens (human)	Licochalcone B results in increased expression of ABCA10 mRNA	https://ctdbase.org/detail.go?type=gene&acc=10349
BIMP091110	ABCA10	ABCA10	Homo sapiens (human)	Testosterone results in decreased expression of ABCA10 mRNA	https://ctdbase.org/detail.go?type=gene&acc=10349
BIMP094277	ABCA10	ABCA10	Homo sapiens (human)	Bisphenol A results in increased expression of ABCA10 mRNA	https://ctdbase.org/detail.go?type=gene&acc=10349
BIMP068482	ABCA10	ABCA10	Homo sapiens (human)	Benzo(a)pyrene results in decreased expression of ABCA10 mRNA	https://ctdbase.org/detail.go?type=gene&acc=10349
BIMP068482	ABCA10	ABCA10	Homo sapiens (human)	Benzo(a)pyrene results in increased methylation of ABCA10 promoter	https://ctdbase.org/detail.go?type=gene&acc=10349
BIMP032227	ABCA10	ABCA10	Homo sapiens (human)	[docetaxel results in decreased susceptibility to docetaxel] which results in increased expression of ABCA10 mRNA	https://ctdbase.org/detail.go?type=gene&acc=10349
BIMP026639	ABCA10	ABCA10	Homo sapiens (human)	N-nitrosopyrrolidine results in decreased expression of ABCA10 mRNA	https://ctdbase.org/detail.go?type=gene&acc=10349

BIMP082124

ABCA1

Homo sapiens (human)

PLD2 protein inhibits the reaction [linoleic acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased export of cholesterol]]]|linoleic acid results in increased degradation of ABCA1 protein|1-butanol inhibits the reaction [linoleic acid inhibits the reaction [ABCA1 protein results in increased export of cholesterol]]|linoleic acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of phospholipids]]|triacsin C inhibits the reaction [linoleic acid inhibits the reaction [ABCA1 protein results in increased transport of phospholipids]]|triacsin C inhibits the reaction [linoleic acid results in increased degradation of ABCA1 protein]|linoleic acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of cholesterol]]|linoleic acid inhibits the reaction [ABCA1 protein results in increased export of cholesterol]|triacsin C inhibits the reaction [linoleic acid inhibits the reaction [ABCA1 protein results in increased transport of cholesterol]]|linoleic acid results in increased phosphorylation of ABCA1 protein