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Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
ABCA1
|
Gallus gallus (chicken)
|
Folic acid results in decreased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
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ABCA1
|
Homo sapiens (human)
|
[folic acid deficiency co-treated with methotrexate] results in increased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Homo sapiens (human)
|
Folic acid results in increased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Mus musculus (house mouse)
|
Folic acid results in decreased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Mus musculus (house mouse)
|
1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid inhibits the reaction [capsaicin results in increased expression of ABCA1 protein]|trpv1 gene mutant form inhibits the reaction [capsaicin results in increased expression of ABCA1 protein]|apoe affects the reaction [capsaicin results in increased expression of ABCA1 protein]|[capsaicin results in increased expression of ABCA1 protein] which results in decreased uptake of cholesterol|capsaicin results in increased expression of ABCA1 protein|abca1 results in increased susceptibility to capsaicin|kt 5720 inhibits the reaction [capsaicin results in increased expression of ABCA1 protein]|[capsaicin results in increased expression of ABCA1 protein] which results in increased secretion of cholesterol|cyclosporine affects the reaction [capsaicin results in increased expression of ABCA1 protein]
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Homo sapiens (human)
|
Tetramethylpyrazine results in increased expression of ABCA1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Homo sapiens (human)
|
[docetaxel results in decreased susceptibility to docetaxel] which results in increased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Mesocricetus auratus (golden hamster)
|
9,11-linoleic acid results in increased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Homo sapiens (human)
|
Trans-10,cis-12-conjugated linoleic acid results in decreased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Homo sapiens (human)
|
[genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Homo sapiens (human)
|
Genistein results in increased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Mus musculus (house mouse)
|
[vancomycin co-treated with neomycin co-treated with ampicillin co-treated with metronidazole co-treated with amphotericin B] results in decreased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Homo sapiens (human)
|
[genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Homo sapiens (human)
|
Amentoflavone inhibits the reaction [malondialdehyde-low density lipoprotein, human results in decreased expression of ABCA1 protein]
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Homo sapiens (human)
|
|
https://www.dgidb.org/genes/hgnc:29
|
||
|
ABCA1
|
Mus musculus (house mouse)
|
Triolein results in decreased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Rattus norvegicus (Norway rat)
|
Mifepristone results in decreased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Mus musculus (house mouse)
|
Pirinixic acid results in increased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Homo sapiens (human)
|
[pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Mus musculus (house mouse)
|
[pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Homo sapiens (human)
|
[LG 100268 co-treated with [ascorbic acid co-treated with beta-glycerophosphoric acid co-treated with dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 mrna|diazepinylbenzoic acid inhibits the reaction [[LG 100268 co-treated with [ascorbic acid co-treated with beta-glycerophosphoric acid co-treated with dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 mrna]|[ascorbic acid co-treated with beta-glycerophosphoric acid co-treated with dexamethasone co-treated with INS protein] results in increased expression of ABCA1 mrna|[rosiglitazone co-treated with [ascorbic acid co-treated with beta-glycerophosphoric acid co-treated with dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 protein|[bexarotene co-treated with [ascorbic acid co-treated with beta-glycerophosphoric acid co-treated with dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 protein|diazepinylbenzoic acid inhibits the reaction [[tributyltin co-treated with [ascorbic acid co-treated with beta-glycerophosphoric acid co-treated with dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 mrna]|[tributyltin co-treated with [ascorbic acid co-treated with beta-glycerophosphoric acid co-treated with dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 protein|[tributyltin co-treated with [ascorbic acid co-treated with beta-glycerophosphoric acid co-treated with dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 mrna|[diazepinylbenzoic acid co-treated with [ascorbic acid co-treated with beta-glycerophosphoric acid co-treated with dexamethasone co-treated with INS protein]] results in decreased expression of ABCA1 mrna|[t0901317 co-treated with [ascorbic acid co-treated with beta-glycerophosphoric acid co-treated with dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Homo sapiens (human)
|
[quercetin co-treated with ascorbic acid] results in decreased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Mus musculus (house mouse)
|
Tetracycline results in increased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Mus musculus (house mouse)
|
Trilinolenin results in decreased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Homo sapiens (human)
|
[estradiol co-treated with TGFB1 protein] results in increased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
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