SCFBio, IIT Delhi
Hauz Khas, New Delhi
BIMP
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SCFBio, IIT Delhi
Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
ABCA1
|
Homo sapiens (human)
|
Fluoxetine results in decreased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Mus musculus (house mouse)
|
Doxorubicin results in increased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Homo sapiens (human)
|
Butylated hydroxytoluene inhibits the reaction [iron(ii)-ascorbic acid complex results in decreased expression of ABCA1 protein]|butylated hydroxytoluene results in increased expression of ABCA1 mrna|butylated hydroxytoluene inhibits the reaction [iron(ii)-ascorbic acid complex results in decreased expression of ABCA1 mrna]|[butylated hydroxytoluene co-treated with iron(ii)-ascorbic acid complex] results in increased expression of ABCA1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Mus musculus (house mouse)
|
Tetrachloroethylene results in increased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Homo sapiens (human)
|
Valproic acid affects the expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Homo sapiens (human)
|
Valproic acid results in decreased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Homo sapiens (human)
|
Valproic acid results in increased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Homo sapiens (human)
|
Valproic acid results in increased methylation of ABCA1 gene
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Mus musculus (house mouse)
|
Valproic acid results in increased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Homo sapiens (human)
|
[bezafibrate binds to and results in increased activity of PPARA protein] promotes the reaction [[25-hydroxycholesterol binds to and results in increased activity of NR1H3 protein] which results in increased expression of ABCA1 mrna]|[25-hydroxycholesterol binds to and results in increased activity of NR1H3 protein] which results in increased expression of ABCA1 mrna|[9-deoxy-delta-9-prostaglandin D2 binds to and results in increased activity of PPARG protein] promotes the reaction [[25-hydroxycholesterol binds to and results in increased activity of NR1H3 protein] which results in increased expression of ABCA1 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Homo sapiens (human)
|
[25-hydroxycholesterol co-treated with alitretinoin] results in increased expression of ABCA1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Mus musculus (house mouse)
|
25-hydroxycholesterol results in increased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Rattus norvegicus (Norway rat)
|
[cholesterol co-treated with 25-hydroxycholesterol] results in decreased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Homo sapiens (human)
|
Epigallocatechin gallate results in increased expression of ABCA1 mrna|epigallocatechin gallate results in increased expression of ABCA1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Homo sapiens (human)
|
Chloroquine diphosphate results in decreased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Mus musculus (house mouse)
|
Mevalonic acid inhibits the reaction [mevastatin inhibits the reaction [8-((4-chlorophenyl)thio)cyclic-3',5'-AMP results in increased expression of ABCA1 protein]]
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Rattus norvegicus (Norway rat)
|
Mevastatin affects the expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Homo sapiens (human)
|
Tert-butylhydroperoxide results in increased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Rattus norvegicus (Norway rat)
|
Furan results in increased methylation of ABCA1 gene
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Mus musculus (house mouse)
|
[vancomycin co-treated with neomycin co-treated with ampicillin co-treated with metronidazole co-treated with amphotericin B] results in decreased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Homo sapiens (human)
|
SIRT6 protein promotes the reaction [curcumin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in decreased expression of ABCA1 protein]]|mir125a mRNA inhibits the reaction [curcumin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in decreased expression of ABCA1 protein]]|sirt6 protein promotes the reaction [curcumin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in decreased expression of ABCA1 mrna]]|mir125a mRNA inhibits the reaction [curcumin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in decreased expression of ABCA1 mrna]]|curcumin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in decreased expression of ABCA1 protein]|curcumin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in decreased expression of ABCA1 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Homo sapiens (human)
|
Colforsin promotes the reaction [diethylhexyl phthalate results in decreased expression of ABCA1 mrna]|diethylhexyl phthalate results in decreased expression of ABCA1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Homo sapiens (human)
|
Diethylhexyl phthalate results in decreased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Mus musculus (house mouse)
|
[tetrachlorodibenzodioxin co-treated with bisphenol A co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with diethylhexyl phthalate] promotes the reaction [dietary fats results in increased expression of ABCA1 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Homo sapiens (human)
|
Parathion results in increased methylation of ABCA1 promoter
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
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