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Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
ABCA1
|
Homo sapiens (human)
|
Perfluorobutyric acid results in increased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Homo sapiens (human)
|
Lithocholic acid results in decreased expression of ABCA1 protein|lithocholic acid results in decreased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Mus musculus (house mouse)
|
Lithocholic acid results in increased expression of ABCA1 mrna|nfe2l2 protein promotes the reaction [lithocholic acid results in increased expression of ABCA1 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Homo sapiens (human)
|
Vecuronium bromide inhibits the reaction [nicotine results in decreased expression of ABCA1 mrna]|nicotine results in decreased expression of ABCA1 mrna|nicotine results in decreased expression of ABCA1 protein|gw 3965 inhibits the reaction [nicotine results in decreased expression of ABCA1 mrna]|gw 3965 inhibits the reaction [nicotine results in decreased expression of ABCA1 protein]|vecuronium bromide inhibits the reaction [nicotine results in decreased expression of ABCA1 protein]
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Homo sapiens (human)
|
Bisphenol A results in decreased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Mus musculus (house mouse)
|
[bisphenol A co-treated with LIF protein] results in decreased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Mus musculus (house mouse)
|
Bisphenol A results in decreased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Mus musculus (house mouse)
|
Bisphenol A results in increased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Mus musculus (house mouse)
|
[tetrachlorodibenzodioxin co-treated with bisphenol A co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with diethylhexyl phthalate] promotes the reaction [dietary fats results in increased expression of ABCA1 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Rattus norvegicus (Norway rat)
|
Bisphenol A results in decreased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Rattus norvegicus (Norway rat)
|
Bisphenol A results in increased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Rattus norvegicus (Norway rat)
|
Bisphenol A results in increased methylation of ABCA1 gene
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Rattus norvegicus (Norway rat)
|
Cholesterol inhibits the reaction [bisphenol A results in decreased expression of ABCA1 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Homo sapiens (human)
|
Ethanol results in decreased expression of ABCA1 mrna|igf1 protein inhibits the reaction [ethanol results in decreased expression of ABCA1 mrna]|ethanol results in decreased expression of ABCA1 protein|igf1 protein inhibits the reaction [ethanol results in decreased expression of ABCA1 protein]
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Homo sapiens (human)
|
Ethanol results in increased expression of ABCA1 mrna|ethanol results in increased expression of ABCA1 protein|ethanol results in increased expression of and affects the localization of ABCA1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Mus musculus (house mouse)
|
Ethanol affects the splicing of ABCA1 mrna|ethanol results in increased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Rattus norvegicus (Norway rat)
|
Ethanol results in decreased expression of ABCA1 mrna|ethanol results in decreased expression of ABCA1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Homo sapiens (human)
|
Methyleugenol results in decreased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Homo sapiens (human)
|
Glyoxal inhibits the reaction [ABCA1 protein binds to APOA1 protein]|glyoxal inhibits the reaction [ABCA1 protein results in increased export of cholesterol]|glyoxal results in increased degradation of ABCA1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Mus musculus (house mouse)
|
4-vinyl-1-cyclohexene dioxide affects the expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Homo sapiens (human)
|
ABCA1 protein alternative form affects the susceptibility to rosiglitazone
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Homo sapiens (human)
|
[rosiglitazone co-treated with [ascorbic acid co-treated with beta-glycerophosphoric acid co-treated with dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Homo sapiens (human)
|
[rosiglitazone co-treated with atorvastatin] results in increased expression of ABCA1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Homo sapiens (human)
|
Rosiglitazone results in increased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Homo sapiens (human)
|
Rosiglitazone results in increased expression of ABCA1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
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