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Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
ABCA1
|
Homo sapiens (human)
|
Clofibrate results in increased expression of ABCA1 protein|clofibrate results in increased expression of ABCA1 mrna|ppara protein affects the reaction [clofibrate results in increased expression of ABCA1 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Rattus norvegicus (Norway rat)
|
Ketoconazole inhibits the reaction [clofibrate results in increased expression of ABCA1 mrna]|clofibrate results in increased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Homo sapiens (human)
|
MIR200C mRNA affects the reaction [dibutyl phthalate results in decreased expression of ABCA1 protein]|dibutyl phthalate results in decreased expression of ABCA1 mrna|dibutyl phthalate results in decreased expression of ABCA1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Mesocricetus auratus (golden hamster)
|
[fructose co-treated with dietary fats co-treated with cholesterol, dietary] results in increased expression of ABCA1 mrna|[fructose co-treated with dietary fats co-treated with T0901317] results in increased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Rattus norvegicus (Norway rat)
|
Fructose results in increased expression of ABCA1 mrna|tea inhibits the reaction [fructose results in increased expression of ABCA1 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Rattus norvegicus (Norway rat)
|
[permethrin co-treated with DEET] results in decreased methylation of ABCA1 gene
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Mus musculus (house mouse)
|
Isoproterenol results in increased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Mus musculus (house mouse)
|
Mevalonic acid inhibits the reaction [mevastatin inhibits the reaction [8-((4-chlorophenyl)thio)cyclic-3',5'-AMP results in increased expression of ABCA1 protein]]
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Homo sapiens (human)
|
6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [iron(ii)-ascorbic acid complex results in decreased expression of ABCA1 mrna]|6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [iron(ii)-ascorbic acid complex results in decreased expression of ABCA1 protein]
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Mus musculus (house mouse)
|
Desmosterol results in increased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Mus musculus (house mouse)
|
Tosylphenylalanyl chloromethyl ketone inhibits the reaction [lipopolysaccharide, escherichia coli O111 B4 results in decreased expression of ABCA1 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Homo sapiens (human)
|
Oleic acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of phospholipids]]|oleic acid results in increased phosphorylation of ABCA1 protein|oleic acid results in increased degradation of ABCA1 protein|oleic acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of cholesterol]]
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Homo sapiens (human)
|
[palmitic acid co-treated with oleic acid] affects the expression of ABCA1 mrna|[palmitic acid co-treated with oleic acid co-treated with TNF protein] affects the expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Mus musculus (house mouse)
|
Oleic acid results in increased expression of ABCA1 mrna|oleic acid inhibits the reaction [27-hydroxycholesterol results in increased expression of ABCA1 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Mus musculus (house mouse)
|
Docosahexaenoic acids results in increased expression of ABCA1 mrna|docosahexaenoic acids inhibits the reaction [27-hydroxycholesterol results in increased expression of ABCA1 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Homo sapiens (human)
|
PPARG protein promotes the reaction [resveratrol results in increased expression of ABCA1 protein]|2-chloro-5-nitrobenzanilide inhibits the reaction [resveratrol results in increased expression of ABCA1 mrna]|adora2a protein promotes the reaction [resveratrol results in increased expression of ABCA1 protein]|zm 241385 inhibits the reaction [resveratrol results in increased expression of ABCA1 protein]|pparg protein promotes the reaction [resveratrol results in increased expression of ABCA1 mrna]|2-chloro-5-nitrobenzanilide inhibits the reaction [resveratrol results in increased expression of ABCA1 protein]
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Homo sapiens (human)
|
Resveratrol results in decreased expression of ABCA1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Homo sapiens (human)
|
Resveratrol results in increased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Homo sapiens (human)
|
Resveratrol results in increased expression of ABCA1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Homo sapiens (human)
|
[resveratrol results in increased expression of ABCA1 protein] which results in increased secretion of cholesterol
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Homo sapiens (human)
|
Arachidonic acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of phospholipids]]|arachidonic acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of cholesterol]]|arachidonic acid results in increased degradation of ABCA1 protein
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Homo sapiens (human)
|
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased expression of ABCA1 mrna|methotrexate inhibits the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased expression of ABCA1 mrna]|zm 241385 inhibits the reaction [methotrexate inhibits the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased expression of ABCA1 mrna]]
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Homo sapiens (human)
|
Eicosapentaenoic acid results in decreased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Mus musculus (house mouse)
|
PPARA protein promotes the reaction [eicosapentaenoic acid results in increased expression of ABCA1 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
||
|
ABCA1
|
Rattus norvegicus (Norway rat)
|
Gentamicins results in increased expression of ABCA1 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=19
|
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