Molecular Targets : Dataset Browser

BIMP_ID	Target Name	Gene	Organism	Action	Source URL
BIMP091110	ACE	ACE	Rattus norvegicus (Norway rat)	[estradiol co-treated with testosterone] results in increased expression of ACE mRNA	https://ctdbase.org/detail.go?type=gene&acc=1636
BIMP091243	ACE	ACE	Homo sapiens (human)	ACE protein affects the susceptibility to phenylephrine	https://ctdbase.org/detail.go?type=gene&acc=1636
BIMP082566	ACE	ACE	Homo sapiens (human)	Lasiocarpine metabolite results in decreased expression of ACE mRNA	https://ctdbase.org/detail.go?type=gene&acc=1636
BIMP082231	ACE	ACE	Rattus norvegicus (Norway rat)	Genistein results in increased expression of ACE mrna\|[genistein co-treated with methoxychlor] results in increased expression of ACE mRNA	https://ctdbase.org/detail.go?type=gene&acc=1636
BIMP082231	ACE	ACE	Rattus norvegicus (Norway rat)	Genistein inhibits the reaction [aldosterone results in increased expression of ACE mrna]	https://ctdbase.org/detail.go?type=gene&acc=1636
BIMP082286	ACE	ACE	Oryctolagus cuniculus (rabbit)	Butein results in decreased activity of ACE protein	https://ctdbase.org/detail.go?type=gene&acc=1636
BIMP082431	ACE	ACE	Rattus norvegicus (Norway rat)	Oleuropein inhibits the reaction [isoproterenol results in increased activity of ACE protein]	https://ctdbase.org/detail.go?type=gene&acc=1636
BIMP080575	ACE-1	ace-1	Anopheles gambiae (African malaria mosquito)	PARA-LIKE protein mutant form promotes the reaction [ACE-1 protein mutant form results in decreased susceptibility to propoxur]\|ace-1 protein mutant form results in decreased susceptibility to propoxur	https://ctdbase.org/detail.go?type=gene&acc=181706
BIMP070852	ACE-1	ace-1	Bursaphelenchus xylophilus (pine wood nematode)	ACE-3 protein inhibits the reaction [carbofuran results in decreased activity of ACE-1 protein]\|carbofuran results in decreased activity of ACE-1 protein	https://ctdbase.org/detail.go?type=gene&acc=181706
BIMP073605	ACE-1	ace-1	Anopheles gambiae (African malaria mosquito)	ACE-1 protein mutant form inhibits the reaction [PARA-LIKE protein mutant form results in decreased susceptibility to permethrin]\|ace-1 protein mutant form results in decreased susceptibility to permethrin	https://ctdbase.org/detail.go?type=gene&acc=181706
BIMP071820	ACE-1	ace-1	Bursaphelenchus xylophilus (pine wood nematode)	ACE-3 protein inhibits the reaction [dichlorvos results in decreased activity of ACE-1 protein]\|dichlorvos results in decreased activity of ACE-1 protein	https://ctdbase.org/detail.go?type=gene&acc=181706
BIMP071820	ACE-1	ace-1	Caenorhabditis elegans	Dichlorvos results in decreased activity of ACE-1 protein	https://ctdbase.org/detail.go?type=gene&acc=181706
BIMP071820	ACE-2	ace-2	Bursaphelenchus xylophilus (pine wood nematode)	ACE-3 protein inhibits the reaction [dichlorvos results in decreased activity of ACE-2 protein]\|dichlorvos results in decreased activity of ACE-2 protein	https://ctdbase.org/detail.go?type=gene&acc=171905
BIMP070852	ACE-2	ace-2	Bursaphelenchus xylophilus (pine wood nematode)	Carbofuran results in decreased activity of ACE-2 protein\|ace-3 protein inhibits the reaction [carbofuran results in decreased activity of ACE-2 protein]	https://ctdbase.org/detail.go?type=gene&acc=171905
BIMP070852	ACE-3	ace-3	Bursaphelenchus xylophilus (pine wood nematode)	ACE-3 protein inhibits the reaction [carbofuran results in decreased activity of ACE-2 protein]\|ace-3 protein inhibits the reaction [carbofuran results in decreased activity of ACE-1 protein]	https://ctdbase.org/detail.go?type=gene&acc=175076
BIMP071820	ACE-3	ace-3	Bursaphelenchus xylophilus (pine wood nematode)	ACE-3 protein inhibits the reaction [dichlorvos results in decreased activity of ACE-2 protein]\|ace-3 protein inhibits the reaction [dichlorvos results in decreased activity of ACE-1 protein]	https://ctdbase.org/detail.go?type=gene&acc=175076
BIMP088120	ACE-3	ace-3	Caenorhabditis elegans	[sodium arsenite results in increased abundance of arsenite] which results in decreased expression of ACE-3 mRNA	https://ctdbase.org/detail.go?type=gene&acc=175076
BIMP087516	ACE1	ACE1	Rhopalosiphum padi (bird cherry-oat aphid)	ACE1 gene mutant form results in decreased susceptibility to monocrotophos	https://ctdbase.org/detail.go?type=gene&acc=5657353
BIMP080575	ACE1	ACE1	Anopheles gambiae (African malaria mosquito)	ACE1 gene mutant form results in decreased susceptibility to propoxur	https://ctdbase.org/detail.go?type=gene&acc=5657353
BIMP093437	ACE1	ACE1	Homo sapiens (human)	Cannabidiol results in increased expression of ACE1 mRNA	https://ctdbase.org/detail.go?type=gene&acc=5657353
BIMP105492	ACE1	ACE1	Culex pipiens (northern house mosquito)	ACE1 gene mutant form results in decreased susceptibility to parathion	https://ctdbase.org/detail.go?type=gene&acc=5657353
BIMP105229	ACE2	ACE2	Homo sapiens (human)	3-hydroxy-4-prenyl-5-methoxystilbene-2-carboxylic acid analog results in decreased expression of ACE2 mRNA	https://ctdbase.org/detail.go?type=gene&acc=59272
BIMP101315	ACE2	ACE2	Rattus norvegicus (Norway rat)	[ampicillin co-treated with neomycin co-treated with gentamicins co-treated with metronidazole co-treated with vancomycin] results in increased expression of ACE2 protein	https://ctdbase.org/detail.go?type=gene&acc=59272
BIMP101570	ACE2	ACE2	Rattus norvegicus (Norway rat)	Pyrazolanthrone inhibits the reaction [7-ala-angiotensin (1-7) inhibits the reaction [ACE2 protein inhibits the reaction [lipopolysaccharides results in increased expression of IL1B protein]]]\|pyrazolanthrone inhibits the reaction [2-(1-carboxy-2-(3-(3,5-dichlorobenzyl)-3H-imidazol-4-yl)ethylamino)-4-methylpentanoic acid inhibits the reaction [ACE2 protein inhibits the reaction [lipopolysaccharides results in increased expression of TNF protein]]]\|pyrazolanthrone inhibits the reaction [7-ala-angiotensin (1-7) inhibits the reaction [ACE2 protein inhibits the reaction [lipopolysaccharides results in increased expression of TNF protein]]]\|pyrazolanthrone inhibits the reaction [2-(1-carboxy-2-(3-(3,5-dichlorobenzyl)-3H-imidazol-4-yl)ethylamino)-4-methylpentanoic acid inhibits the reaction [ACE2 protein inhibits the reaction [lipopolysaccharides results in increased expression of IL1B protein]]]	https://ctdbase.org/detail.go?type=gene&acc=59272
BIMP101100	ACE2	ACE2	Homo sapiens (human)	Pentanal results in increased expression of ACE2 mRNA	https://ctdbase.org/detail.go?type=gene&acc=59272

BIMP091110

ACE

Rattus norvegicus (Norway rat)

[estradiol co-treated with testosterone] results in increased expression of ACE mRNA