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Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
ACE
|
Oryzias latipes (Japanese medaka)
|
Estradiol results in decreased expression of ACE mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1636
|
||
|
ACE
|
Rattus norvegicus (Norway rat)
|
[estradiol co-treated with testosterone] results in increased expression of ACE mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1636
|
||
|
ACE
|
Oryctolagus cuniculus (rabbit)
|
Luteolin results in decreased activity of ACE protein
|
https://ctdbase.org/detail.go?type=gene&acc=1636
|
||
|
ACE
|
Rattus norvegicus (Norway rat)
|
Flavonoids results in decreased expression of ACE mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1636
|
||
|
ACE
|
Mus musculus (house mouse)
|
Quercetin affects the reaction [dietary fats affects the activity of ACE protein]|quercetin affects the reaction [dietary fats affects the expression of ACE mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=1636
|
||
|
ACE
|
Rattus norvegicus (Norway rat)
|
Quercetin inhibits the reaction [colchicine results in decreased activity of ACE protein]
|
https://ctdbase.org/detail.go?type=gene&acc=1636
|
||
|
ACE
|
Rattus norvegicus (Norway rat)
|
Quercetin results in increased expression of ACE mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1636
|
||
|
ACE
|
Rattus norvegicus (Norway rat)
|
Pioglitazone inhibits the reaction [streptozocin results in increased expression of ACE protein]|pioglitazone inhibits the reaction [streptozocin results in increased expression of ACE mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=1636
|
||
|
ACE
|
Homo sapiens (human)
|
[butyrates co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] affects the localization of ACE protein mutant form|[butyrates co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased activity of ACE protein mutant form
|
https://ctdbase.org/detail.go?type=gene&acc=1636
|
||
|
ACE
|
Homo sapiens (human)
|
ACE inhibits the reaction [cocaine affects the abundance of dinoprostone]
|
https://ctdbase.org/detail.go?type=gene&acc=1636
|
||
|
ACE
|
Oryctolagus cuniculus (rabbit)
|
Apigenin results in decreased activity of ACE protein
|
https://ctdbase.org/detail.go?type=gene&acc=1636
|
||
|
ACE
|
Mus musculus (house mouse)
|
Diisononyl phthalate results in increased expression of ACE protein|diisononyl phthalate promotes the reaction [dexamethasone results in increased expression of ACE protein]|enalapril inhibits the reaction [diisononyl phthalate promotes the reaction [dexamethasone results in increased expression of ACE protein]]
|
https://ctdbase.org/detail.go?type=gene&acc=1636
|
||
|
ACE
|
Rattus norvegicus (Norway rat)
|
Spironolactone affects the expression of ACE protein
|
https://ctdbase.org/detail.go?type=gene&acc=1636
|
||
|
ACE
|
Rattus norvegicus (Norway rat)
|
Spironolactone inhibits the reaction [aldosterone results in increased activity of ACE protein]|spironolactone inhibits the reaction [aldosterone results in increased expression of ACE mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=1636
|
||
|
ACE
|
Rattus norvegicus (Norway rat)
|
Spironolactone results in decreased expression of ACE protein
|
https://ctdbase.org/detail.go?type=gene&acc=1636
|
||
|
ACE
|
Homo sapiens (human)
|
|
https://www.dgidb.org/genes/hgnc:2707
|
||
|
ACE
|
Mus musculus (house mouse)
|
Pirinixic acid results in decreased expression of ACE mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1636
|
||
|
ACE
|
Rattus norvegicus (Norway rat)
|
Mifepristone inhibits the reaction [corticosterone results in increased expression of ACE mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=1636
|
||
|
ACE
|
Rattus norvegicus (Norway rat)
|
Mifepristone inhibits the reaction [dexamethasone results in increased expression of ACE mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=1636
|
||
|
ACE
|
Homo sapiens (human)
|
Ascorbic acid inhibits the reaction [epigallocatechin gallate results in decreased activity of ACE protein]
|
https://ctdbase.org/detail.go?type=gene&acc=1636
|
||
|
ACE
|
Homo sapiens (human)
|
Triclosan results in decreased expression of ACE mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1636
|
||
|
ACE
|
Mus musculus (house mouse)
|
Trigonelline inhibits the reaction [glucose results in increased expression of ACE mrna]|oltipraz affects the reaction [trigonelline affects the reaction [INS2 protein affects the expression of ACE mrna]]|oltipraz affects the reaction [trigonelline affects the reaction [INS2 protein affects the expression of ACE protein]]|oltipraz inhibits the reaction [trigonelline inhibits the reaction [glucose results in increased expression of ACE mrna]]|trigonelline affects the reaction [INS2 protein affects the expression of ACE mrna]|trigonelline affects the reaction [INS2 protein affects the expression of ACE protein]
|
https://ctdbase.org/detail.go?type=gene&acc=1636
|
||
|
ACE
|
Mus musculus (house mouse)
|
[tetrachlorodibenzodioxin co-treated with ethinyl estradiol] results in increased expression of ACE mrna|ethinyl estradiol results in increased expression of ACE mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1636
|
||
|
ACE
|
Xenopus tropicalis (tropical clawed frog)
|
Ethinyl estradiol results in decreased expression of ACE mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1636
|
||
|
ACE
|
Homo sapiens (human)
|
Testosterone results in decreased expression of ACE mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=1636
|
No matching records found on this page.