Molecular Targets : Dataset Browser

BIMP_ID	Target Name	Gene	Organism	Action	Source URL
BIMP017672	ACE	ACE	Mus musculus (house mouse)	APLN protein modified form inhibits the reaction [uric acid results in increased expression of ACE mrna]\|uric acid results in increased expression of ACE mRNA	https://ctdbase.org/detail.go?type=gene&acc=1636
BIMP011298	ACE	ACE	Homo sapiens (human)	[butyrates co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] affects the localization of ACE protein mutant form\|[butyrates co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased activity of ACE protein mutant form\|[butyrates co-treated with bortezomib] results in increased activity of ACE protein mutant form	https://ctdbase.org/detail.go?type=gene&acc=1636
BIMP009842	ACE	ACE	Rattus norvegicus (Norway rat)	Indican results in increased expression of ACE mRNA	https://ctdbase.org/detail.go?type=gene&acc=1636
BIMP012916	ACE	ACE	Oryctolagus cuniculus (rabbit)	Proanthocyanidins results in decreased activity of ACE protein	https://ctdbase.org/detail.go?type=gene&acc=1636
BIMP016143	ACE	ACE	Homo sapiens (human)	[toluene co-treated with ethylbenzene co-treated with xylenes] results in increased expression of ACE mrna\|[toluene co-treated with ethylbenzene co-treated with xylenes] results in decreased methylation of ACE gene	https://ctdbase.org/detail.go?type=gene&acc=1636
BIMP088120	ACE	ACE	Mus musculus (house mouse)	Arsenite results in decreased expression of ACE mRNA	https://ctdbase.org/detail.go?type=gene&acc=1636
BIMP087826	ACE	ACE	Homo sapiens (human)	ACE gene polymorphism inhibits the reaction [[enalapril co-treated with sodium chloride] results in increased susceptibility to AGT protein modified form]\|ace gene polymorphism affects the susceptibility to [enalapril co-treated with sodium chloride]	https://ctdbase.org/detail.go?type=gene&acc=1636
BIMP087826	ACE	ACE	Homo sapiens (human)	Enalapril results in decreased activity of ACE protein	https://ctdbase.org/detail.go?type=gene&acc=1636
BIMP087826	ACE	ACE	Mus musculus (house mouse)	Enalapril inhibits the reaction [dexamethasone results in increased expression of ACE protein]\|enalapril inhibits the reaction [diisononyl phthalate promotes the reaction [dexamethasone results in increased expression of ACE protein]]	https://ctdbase.org/detail.go?type=gene&acc=1636
BIMP087826	ACE	ACE	Mus musculus (house mouse)	Enalapril inhibits the reaction [formaldehyde results in increased expression of ACE protein]	https://ctdbase.org/detail.go?type=gene&acc=1636
BIMP087826	ACE	ACE	Rattus norvegicus (Norway rat)	Enalapril inhibits the reaction [streptozocin results in increased expression of ACE protein]\|enalapril inhibits the reaction [streptozocin results in increased expression of ACE mrna]	https://ctdbase.org/detail.go?type=gene&acc=1636
BIMP087826	ACE	ACE	Rattus norvegicus (Norway rat)	Enalapril promotes the reaction [folic acid results in increased expression of ACE mrna]\|enalapril results in increased expression of ACE mRNA	https://ctdbase.org/detail.go?type=gene&acc=1636
BIMP087826	ACE	ACE	Rattus norvegicus (Norway rat)	Enalapril results in decreased activity of ACE protein	https://ctdbase.org/detail.go?type=gene&acc=1636
BIMP087826	ACE	ACE	Homo sapiens (human)	Enalapril inhibits the reaction [ACE protein results in increased degradation of KNG1 protein modified form]\|enalapril inhibits the reaction [ACE protein results in increased degradation of TAC1 protein modified form]	https://ctdbase.org/detail.go?type=gene&acc=1636
BIMP087826	ACE	ACE	Homo sapiens (human)	Enalapril results in decreased activity of ACE protein	https://ctdbase.org/detail.go?type=gene&acc=1636
BIMP083376	ACE	ACE	Homo sapiens (human)	Herbimycin inhibits the reaction [VEGFA protein results in increased expression of ACE protein]	https://ctdbase.org/detail.go?type=gene&acc=1636
BIMP082941	ACE	ACE	Mus musculus (house mouse)	Fenretinide results in decreased expression of ACE mRNA	https://ctdbase.org/detail.go?type=gene&acc=1636
BIMP085543	ACE	ACE	Homo sapiens (human)	Spiraeoside results in decreased activity of ACE protein	https://ctdbase.org/detail.go?type=gene&acc=1636
BIMP087317	ACE	ACE	Moina macrocopa	Methoprene affects the expression of ACE mRNA	https://ctdbase.org/detail.go?type=gene&acc=1636
BIMP087317	ACE	ACE	Daphnia magna	Methoprene results in decreased expression of ACE mRNA	https://ctdbase.org/detail.go?type=gene&acc=1636
BIMP090429	ACE	ACE	Mus musculus (house mouse)	Dexamethasone results in increased expression of ACE mRNA	https://ctdbase.org/detail.go?type=gene&acc=1636
BIMP090429	ACE	ACE	Mus musculus (house mouse)	Dexamethasone results in increased expression of ACE protein\|enalapril inhibits the reaction [dexamethasone results in increased expression of ACE protein]\|diisononyl phthalate promotes the reaction [dexamethasone results in increased expression of ACE protein]\|enalapril inhibits the reaction [diisononyl phthalate promotes the reaction [dexamethasone results in increased expression of ACE protein]]	https://ctdbase.org/detail.go?type=gene&acc=1636
BIMP090429	ACE	ACE	Rattus norvegicus (Norway rat)	Dexamethasone results in decreased activity of ACE protein	https://ctdbase.org/detail.go?type=gene&acc=1636
BIMP090429	ACE	ACE	Rattus norvegicus (Norway rat)	Mifepristone inhibits the reaction [dexamethasone results in increased expression of ACE mrna]\|dexamethasone results in increased expression of ACE mRNA	https://ctdbase.org/detail.go?type=gene&acc=1636
BIMP090429	ACE	ACE	Rattus norvegicus (Norway rat)	Dexamethasone results in increased expression of ACE protein\|[lithium chloride co-treated with pilocarpine] affects the reaction [dexamethasone results in increased expression of ACE mrna]\|[lithium chloride co-treated with pilocarpine] affects the reaction [dexamethasone results in increased expression of ACE protein]	https://ctdbase.org/detail.go?type=gene&acc=1636

BIMP017672

ACE

Mus musculus (house mouse)

APLN protein modified form inhibits the reaction [uric acid results in increased expression of ACE mrna]|uric acid results in increased expression of ACE mRNA