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SCFBio, IIT Delhi Hauz Khas, New Delhi
MOLECULAR TARGET

ACE2

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81

Interactions

Homo sapiens (human)

Organism

ACE2

Gene Name

Compound Associations

S.No BIMP ID Organism Action References
1 BIMP105229 Homo sapiens (human) 3-hydroxy-4-prenyl-5-methoxystilbene-2-carboxylic acid analog results in decreased expression of ACE2 mRNA
2 BIMP101100 Homo sapiens (human) Pentanal results in increased expression of ACE2 mRNA
3 BIMP101315 Homo sapiens (human) [ampicillin co-treated with neomycin co-treated with gentamicins co-treated with metronidazole co-treated with vancomycin] results in increased expression of ACE2 protein
4 BIMP101570 Homo sapiens (human) Pyrazolanthrone inhibits the reaction [7-ala-angiotensin (1-7) inhibits the reaction [ACE2 protein inhibits the reaction [lipopolysaccharides results in increased expression of IL1B protein]]]|pyrazolanthrone inhibits the reaction [2-(1-carboxy-2-(3-(3,5-dichlorobenzyl)-3H-imidazol-4-yl)ethylamino)-4-methylpentanoic acid inhibits the reaction [ACE2 protein inhibits the reaction [lipopolysaccharides results in increased expression of TNF protein]]]|pyrazolanthrone inhibits the reaction [7-ala-angiotensin (1-7) inhibits the reaction [ACE2 protein inhibits the reaction [lipopolysaccharides results in increased expression of TNF protein]]]|pyrazolanthrone inhibits the reaction [2-(1-carboxy-2-(3-(3,5-dichlorobenzyl)-3H-imidazol-4-yl)ethylamino)-4-methylpentanoic acid inhibits the reaction [ACE2 protein inhibits the reaction [lipopolysaccharides results in increased expression of IL1B protein]]]
5 BIMP102821 Homo sapiens (human) Melatonin inhibits the reaction [cadmium chloride results in decreased expression of ACE2 protein]
6 BIMP104532 Homo sapiens (human) [streptozocin co-treated with niacinamide] results in decreased expression of ACE2 mrna|2,5-dihydroxybenzoic acid inhibits the reaction [[streptozocin co-treated with niacinamide] results in decreased expression of ACE2 mrna]|metformin inhibits the reaction [[streptozocin co-treated with niacinamide] results in decreased expression of ACE2 mrna]
7 BIMP104555 Homo sapiens (human) Magnolol inhibits the reaction [monocrotaline results in decreased expression of ACE2 protein]|monocrotaline results in decreased expression of ACE2 protein
8 BIMP104555 Homo sapiens (human) [monocrotaline co-treated with angiotensin I (1-7)] results in increased expression of ACE2 mRNA
9 BIMP105027 Homo sapiens (human) Curcumin inhibits the reaction [AGT protein results in increased expression of ACE2 protein]
10 BIMP105027 Homo sapiens (human) Curcumin binds to ACE2 protein
11 BIMP094130 Homo sapiens (human) Triptonide results in increased expression of ACE2 mRNA
12 BIMP095242 Homo sapiens (human) Xanthone inhibits the reaction [[isoproterenol results in decreased activity of ACE2 protein] which results in decreased abundance of angiotensin I (1-7)]|xanthone inhibits the reaction [isoproterenol results in decreased activity of ACE2 protein]
13 BIMP095242 Homo sapiens (human) Xanthone inhibits the reaction [LEP protein results in increased expression of ace2]|xanthone inhibits the reaction [LEP protein results in increased activity of ACE2 protein]
14 BIMP095241 Homo sapiens (human) Ethanol results in decreased expression of ACE2 mRNA
15 BIMP091110 Homo sapiens (human) [estradiol 3-benzoate co-treated with [testosterone co-treated with estradiol]] results in decreased expression of ACE2 mRNA
16 BIMP091521 Homo sapiens (human) Colchicine results in decreased expression of ACE2 mRNA
17 BIMP096881 Homo sapiens (human) Magnolol inhibits the reaction [monocrotaline results in decreased expression of ACE2 protein]
18 BIMP100631 Homo sapiens (human) Rosiglitazone results in decreased expression of ACE2 mRNA
19 BIMP100888 Homo sapiens (human) Hydroquinone results in decreased expression of ACE2 mRNA
20 BIMP094277 Homo sapiens (human) Bisphenol A results in decreased expression of ACE2 mRNA
21 BIMP094277 Homo sapiens (human) Bisphenol A results in increased expression of ACE2 mrna|bisphenol A results in increased expression of ACE2 protein
22 BIMP080495 Homo sapiens (human) Pioglitazone results in increased expression of ACE2 protein
23 BIMP080495 Homo sapiens (human) Pioglitazone results in increased secretion of ACE2 protein
24 BIMP079668 Homo sapiens (human) ERN1 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ACE2 protein]|benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ACE2 protein|atf6 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ACE2 protein]
25 BIMP079768 Homo sapiens (human) Papaverine results in decreased expression of ACE2 mRNA
26 BIMP077156 Homo sapiens (human) Vitamin A results in increased expression of ACE2 mRNA
27 BIMP090535 Homo sapiens (human) [estradiol 3-benzoate co-treated with [testosterone co-treated with estradiol]] results in decreased expression of ACE2 mRNA
28 BIMP090429 Homo sapiens (human) Dexamethasone results in increased expression of ACE2 mRNA
29 BIMP090429 Homo sapiens (human) Dexamethasone results in decreased expression of ACE2 mRNA
30 BIMP089937 Homo sapiens (human) [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of ACE2 mRNA
31 BIMP089402 Homo sapiens (human) Trigonelline affects the reaction [INS2 protein affects the expression of ACE2 mrna]|oltipraz inhibits the reaction [trigonelline inhibits the reaction [glucose results in decreased expression of ACE2 mrna]]|oltipraz affects the reaction [trigonelline affects the reaction [INS2 protein affects the expression of ACE2 mrna]]|oltipraz affects the reaction [trigonelline affects the reaction [INS2 protein affects the expression of ACE2 protein]]|trigonelline inhibits the reaction [glucose results in decreased expression of ACE2 mrna]|trigonelline affects the reaction [INS2 protein affects the expression of ACE2 protein]
32 BIMP089374 Homo sapiens (human) Triclosan results in decreased expression of ACE2 mRNA
33 BIMP082880 Homo sapiens (human) Cyclosporine results in decreased expression of ACE2 mRNA
34 BIMP088120 Homo sapiens (human) Arsenite inhibits the reaction [G3BP1 protein binds to ACE2 mrna]
35 BIMP087317 Homo sapiens (human) Methoprene results in decreased expression of ACE2 mRNA
36 BIMP088673 Homo sapiens (human) Tetracycline results in increased expression of ACE2 mRNA
37 BIMP088640 Homo sapiens (human) [quercetin co-treated with ascorbic acid] results in decreased expression of ACE2 mRNA
38 BIMP090682 Homo sapiens (human) Spironolactone affects the expression of ACE2 protein
39 BIMP090682 Homo sapiens (human) Spironolactone results in increased expression of ACE2 protein
40 BIMP090784 Homo sapiens (human) Estrone results in decreased expression of ACE2 mRNA
41 BIMP091061 Homo sapiens (human) Ethinyl estradiol results in decreased expression of ACE2 mRNA
42 BIMP082095 Homo sapiens (human) [quercetin co-treated with ascorbic acid] results in decreased expression of ACE2 mRNA
43 BIMP082446 Homo sapiens (human) Zearalenone results in decreased expression of ACE2 mRNA
44 BIMP071142 Homo sapiens (human) Chloroquine results in decreased glycosylation of ACE2 protein
45 BIMP071583 Homo sapiens (human) Amphetamine results in increased expression of ACE2 mRNA
46 BIMP071653 Homo sapiens (human) Diazepam results in decreased expression of ACE2 mRNA
47 BIMP074608 Homo sapiens (human) ACE2 gene SNP results in decreased susceptibility to captopril
48 BIMP074608 Homo sapiens (human) Captopril inhibits the reaction [AGT protein results in decreased expression of ACE2 protein]|captopril inhibits the reaction [AGT protein results in decreased expression of ACE2 mrna]|captopril inhibits the reaction [silicon dioxide results in decreased expression of ACE2 mrna]|captopril inhibits the reaction [silicon dioxide results in decreased expression of ACE2 protein]
49 BIMP074608 Homo sapiens (human) Captopril inhibits the reaction [pregabalin results in decreased expression of ACE2 protein]
50 BIMP074634 Homo sapiens (human) Quinidine results in decreased expression of ACE2 mRNA
51 BIMP072777 Homo sapiens (human) [ampicillin co-treated with neomycin co-treated with gentamicins co-treated with metronidazole co-treated with vancomycin] results in increased expression of ACE2 protein
52 BIMP072653 Homo sapiens (human) Fluorouracil results in increased expression of ACE2 mrna|olmesartan medoxomil inhibits the reaction [fluorouracil results in increased expression of ACE2 mrna]
53 BIMP072781 Homo sapiens (human) 2,5-dihydroxybenzoic acid inhibits the reaction [[streptozocin co-treated with niacinamide] results in decreased expression of ACE2 mrna]
54 BIMP072829 Homo sapiens (human) Glyburide results in decreased expression of ACE2 mRNA
55 BIMP072198 Homo sapiens (human) Valproic acid affects the expression of ACE2 mRNA
56 BIMP072198 Homo sapiens (human) Valproic acid results in decreased expression of ACE2 mRNA
57 BIMP072300 Homo sapiens (human) Doxorubicin results in decreased expression of ACE2 mRNA
58 BIMP072300 Homo sapiens (human) Doxorubicin results in increased expression of ACE2 mRNA
59 BIMP072300 Homo sapiens (human) ACE2 protein results in decreased susceptibility to doxorubicin
60 BIMP071726 Homo sapiens (human) Diclofenac results in decreased expression of ACE2 mRNA
61 BIMP072841 Homo sapiens (human) Glyphosate affects the methylation of ACE2 gene
62 BIMP073251 Homo sapiens (human) Isoproterenol results in increased expression of ACE2 mRNA
63 BIMP073251 Homo sapiens (human) Isoproterenol results in decreased activity of ACE2 protein|xanthone inhibits the reaction [[isoproterenol results in decreased activity of ACE2 protein] which results in decreased abundance of angiotensin I (1-7)]|[isoproterenol results in decreased activity of ACE2 protein] which results in decreased abundance of angiotensin I (1-7)|xanthone inhibits the reaction [isoproterenol results in decreased activity of ACE2 protein]
64 BIMP073251 Homo sapiens (human) Isoproterenol results in increased expression of ACE2 protein
65 BIMP073199 Homo sapiens (human) ACE2 gene polymorphism affects the susceptibility to irbesartan
66 BIMP073239 Homo sapiens (human) Isoniazid results in decreased expression of ACE2 mRNA
67 BIMP073529 Homo sapiens (human) Loratadine binds to ACE2 protein
68 BIMP073059 Homo sapiens (human) Etoposide results in decreased expression of ACE2 mRNA
69 BIMP073059 Homo sapiens (human) Etoposide results in increased expression of ACE2 mRNA
70 BIMP070286 Homo sapiens (human) Caffeine results in decreased phosphorylation of ACE2 protein
71 BIMP065145 Homo sapiens (human) [mono-(2-ethylhexyl)phthalate co-treated with tretinoin] results in increased expression of ACE2 mRNA
72 BIMP064420 Homo sapiens (human) Aflatoxin B1 results in decreased methylation of ACE2 gene
73 BIMP064420 Homo sapiens (human) Aflatoxin B1 results in increased expression of ACE2 mRNA
74 BIMP016127 Homo sapiens (human) 2,7-dihydroxynaphthalene results in decreased expression of ACE2 mRNA
75 BIMP020350 Homo sapiens (human) ACE2 protein affects the reaction [[[lisinopril co-treated with thiorphan co-treated with N-benzyloxycarbonylprolylprolinal] affects the metabolism of AGT protein] which results in decreased abundance of angiotensin I (1-7)]|ACE2 protein affects the reaction [[N-benzyloxycarbonylprolylprolinal affects the metabolism of AGT protein] which results in decreased abundance of angiotensin I (1-7)]
76 BIMP016724 Homo sapiens (human) [NOG protein co-treated with phenylmercuric acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ACE2 mRNA
77 BIMP068482 Homo sapiens (human) Benzo(a)pyrene affects the methylation of ACE2 promoter
78 BIMP035572 Homo sapiens (human) Naproxen results in decreased expression of ACE2 mRNA
79 BIMP032534 Homo sapiens (human) [ampicillin co-treated with neomycin co-treated with gentamicins co-treated with metronidazole co-treated with vancomycin] results in increased expression of ACE2 protein
80 BIMP068094 Homo sapiens (human) Atrazine results in decreased expression of ACE2 mRNA
81 BIMP065553 Homo sapiens (human) Theophylline results in decreased expression of ACE2 mRNA