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SCFBio, IIT Delhi Hauz Khas, New Delhi

Molecular Targets

Interactions between compounds and specific gene/protein targets.

Total Rows 750,454
Pages 30,019
BIMP_ID Target Name Gene Organism Action Source URL
ABCG8
Mus musculus (house mouse)
Diosgenin promotes the reaction [ABCG8 protein results in increased secretion of cholesterol]
https://ctdbase.org/detail.go?type=gene&acc=64241
ABCG8
Rattus norvegicus (Norway rat)
[diosgenin results in increased expression of ABCG8 mrna] which results in increased secretion of cholesterol|diosgenin results in increased expression of ABCG8 mRNA
https://ctdbase.org/detail.go?type=gene&acc=64241
ABCG8
Rattus norvegicus (Norway rat)
[ethinyl estradiol co-treated with diosgenin] results in decreased expression of ABCG8 mRNA
https://ctdbase.org/detail.go?type=gene&acc=64241
ABCG8
Mus musculus (house mouse)
[APOE gene mutant form results in increased susceptibility to diethylhexyl phthalate] which results in decreased expression of ABCG8 protein
https://ctdbase.org/detail.go?type=gene&acc=64241
ABCG8
Mus musculus (house mouse)
[tetrachlorodibenzodioxin co-treated with bisphenol A co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with diethylhexyl phthalate] promotes the reaction [dietary fats results in increased expression of ABCG8 mrna]
https://ctdbase.org/detail.go?type=gene&acc=64241
ABCG8
Rattus norvegicus (Norway rat)
Diethylhexyl phthalate results in decreased expression of ABCG8 protein|diethylhexyl phthalate results in decreased expression of ABCG8 mRNA
https://ctdbase.org/detail.go?type=gene&acc=64241
abch1
Danio rerio (zebrafish)
Bisphenol A affects the methylation of ABCH1 intron
https://ctdbase.org/detail.go?type=gene&acc=558667
abch1
Danio rerio (zebrafish)
Diisobutyl phthalate results in increased expression of ABCH1 mRNA
https://ctdbase.org/detail.go?type=gene&acc=558667
abd-A
Drosophila melanogaster (fruit fly)
Bisphenol A results in decreased expression of ABD-A mRNA
https://ctdbase.org/detail.go?type=gene&acc=42037
abd-A
Drosophila melanogaster (fruit fly)
ABD-A affects the susceptibility to vitamin K 3
https://ctdbase.org/detail.go?type=gene&acc=42037
Abd-B
Drosophila melanogaster (fruit fly)
ABD-B affects the susceptibility to vitamin K 3
https://ctdbase.org/detail.go?type=gene&acc=47763
Abd-B
Drosophila melanogaster (fruit fly)
ABD-B gene polymorphism affects the susceptibility to toluene
https://ctdbase.org/detail.go?type=gene&acc=47763
ABL2
Homo sapiens (human)
http://www.t3db.ca/biodb/bio_entities/BE0000435
ABL2
Homo sapiens (human)
Inhibitor
https://www.drugbank.ca/bio_entities/BE0000435
ABL2
Homo sapiens (human)
http://www.t3db.ca/biodb/bio_entities/BE0000435
ABHD1
Rattus norvegicus (Norway rat)
Dexamethasone results in increased expression of ABHD1 mrna|testosterone inhibits the reaction [dexamethasone results in increased expression of ABHD1 mrna]
https://ctdbase.org/detail.go?type=gene&acc=84696
ABHD1
Mus musculus (house mouse)
Pirinixic acid results in increased expression of ABHD1 mRNA
https://ctdbase.org/detail.go?type=gene&acc=84696
ABHD1
Rattus norvegicus (Norway rat)
Pirinixic acid affects the expression of ABHD1 mRNA
https://ctdbase.org/detail.go?type=gene&acc=84696
ABHD1
Rattus norvegicus (Norway rat)
Pirinixic acid results in increased expression of ABHD1 mRNA
https://ctdbase.org/detail.go?type=gene&acc=84696
ABHD1
Rattus norvegicus (Norway rat)
Testosterone inhibits the reaction [dexamethasone results in increased expression of ABHD1 mrna]
https://ctdbase.org/detail.go?type=gene&acc=84696
ABHD1
Homo sapiens (human)
Abrine results in decreased expression of ABHD1 mRNA
https://ctdbase.org/detail.go?type=gene&acc=84696
ABHD1
Rattus norvegicus (Norway rat)
Schizandrin B inhibits the reaction [carbon tetrachloride results in decreased expression of ABHD1 mrna]
https://ctdbase.org/detail.go?type=gene&acc=84696
ABHD1
Mus musculus (house mouse)
Vancomycin results in increased expression of ABHD1 mRNA
https://ctdbase.org/detail.go?type=gene&acc=84696
ABHD1
Mus musculus (house mouse)
Aflatoxin B1 results in increased expression of ABHD1 mRNA
https://ctdbase.org/detail.go?type=gene&acc=84696
ABHD1
Homo sapiens (human)
[bisphenol A co-treated with fulvestrant] results in decreased methylation of ABHD1 gene|bisphenol A results in decreased methylation of ABHD1 gene
https://ctdbase.org/detail.go?type=gene&acc=84696
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