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Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
ABCG8
|
Rattus norvegicus (Norway rat)
|
Aflatoxin B1 results in increased expression of ABCG8 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=64241
|
||
|
ABCG8
|
Mus musculus (house mouse)
|
[vancomycin co-treated with imipenem] affects the expression of ABCG8 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=64241
|
||
|
ABCG8
|
Rattus norvegicus (Norway rat)
|
Schizandrin B inhibits the reaction [carbon tetrachloride results in decreased expression of ABCG8 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=64241
|
||
|
ABCG8
|
Homo sapiens (human)
|
2,4,6-trimethyl-N-((3'-(methylsulfonyl)-4-biphenylyl)methyl)-N-((5-(trifluoromethyl)-2-furanyl)methyl)benzenesulfonamide inhibits the reaction [alisol B 23-acetate results in increased expression of ABCG8 mrna]|alisol B 23-acetate results in increased expression of ABCG8 mrna|2,4,6-trimethyl-N-((3'-(methylsulfonyl)-4-biphenylyl)methyl)-N-((5-(trifluoromethyl)-2-furanyl)methyl)benzenesulfonamide inhibits the reaction [alisol B 23-acetate results in increased expression of ABCG8 protein]
|
https://ctdbase.org/detail.go?type=gene&acc=64241
|
||
|
ABCG8
|
Homo sapiens (human)
|
Alisol B 23-acetate results in increased expression of ABCG8 protein
|
https://ctdbase.org/detail.go?type=gene&acc=64241
|
||
|
ABCG8
|
Homo sapiens (human)
|
Pregna-4,17-diene-3,16-dione inhibits the reaction [alisol B 23-acetate results in increased expression of ABCG8 protein]
|
https://ctdbase.org/detail.go?type=gene&acc=64241
|
||
|
ABCG8
|
Homo sapiens (human)
|
N-nitrosopyrrolidine results in decreased expression of ABCG8 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=64241
|
||
|
ABCG8
|
Mus musculus (house mouse)
|
Cholates promotes the reaction [ABCG8 protein results in increased secretion of cholesterol]|cholates results in increased expression of ABCG8 protein|cholates results in increased expression of ABCG8 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=64241
|
||
|
ABCG8
|
Mus musculus (house mouse)
|
Cholic acid results in increased expression of ABCG8 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=64241
|
||
|
ABCG8
|
Mus musculus (house mouse)
|
[NR1H4 protein mutant form inhibits the reaction [cholic acid results in increased phosphorylation of NR1H4 protein]] which results in decreased expression of ABCG8 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=64241
|
||
|
ABCG8
|
Homo sapiens (human)
|
Aristolochic acid I results in increased expression of ABCG8 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=64241
|
||
|
ABCG8
|
Homo sapiens (human)
|
[glycochenodeoxycholic acid co-treated with deoxycholic acid co-treated with chenodeoxycholic acid co-treated with glycodeoxycholic acid co-treated with glycocholic acid co-treated with tartrazine] results in decreased expression of ABCG8 mrna|[glycochenodeoxycholic acid co-treated with deoxycholic acid co-treated with chenodeoxycholic acid co-treated with glycodeoxycholic acid co-treated with glycocholic acid co-treated with atazanavir sulfate] results in decreased expression of ABCG8 mrna|[glycochenodeoxycholic acid co-treated with deoxycholic acid co-treated with chenodeoxycholic acid co-treated with glycodeoxycholic acid co-treated with glycocholic acid co-treated with 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt] results in decreased expression of ABCG8 mrna|[glycochenodeoxycholic acid co-treated with deoxycholic acid co-treated with chenodeoxycholic acid co-treated with glycodeoxycholic acid co-treated with glycocholic acid co-treated with nefazodone] results in decreased expression of ABCG8 mrna|[glycochenodeoxycholic acid co-treated with deoxycholic acid co-treated with chenodeoxycholic acid co-treated with glycodeoxycholic acid co-treated with glycocholic acid co-treated with cyclosporine] results in decreased expression of ABCG8 mrna|[glycochenodeoxycholic acid co-treated with deoxycholic acid co-treated with chenodeoxycholic acid co-treated with glycodeoxycholic acid co-treated with glycocholic acid co-treated with acetaminophen] results in decreased expression of ABCG8 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=64241
|
||
|
ABCG8
|
Mus musculus (house mouse)
|
Deoxycholic acid results in increased expression of ABCG8 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=64241
|
||
|
ABCG8
|
Mus musculus (house mouse)
|
SLCO1A1 protein affects the susceptibility to [deoxycholic acid results in increased expression of ABCG8 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=64241
|
||
|
ABCG8
|
Danio rerio (zebrafish)
|
Ethanol results in decreased expression of ABCG8 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=64241
|
||
|
ABCG8
|
Mus musculus (house mouse)
|
[tetrachlorodibenzodioxin co-treated with bisphenol A co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with diethylhexyl phthalate] promotes the reaction [dietary fats results in increased expression of ABCG8 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=64241
|
||
|
ABCG8
|
Rattus norvegicus (Norway rat)
|
Bisphenol A affects the expression of ABCG8 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=64241
|
||
|
ABCG8
|
Rattus norvegicus (Norway rat)
|
[bisphenol A co-treated with estradiol] results in increased expression of ABCG8 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=64241
|
||
|
ABCG8
|
Rattus norvegicus (Norway rat)
|
Bisphenol A results in decreased expression of ABCG8 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=64241
|
||
|
ABCG8
|
Homo sapiens (human)
|
Pregna-4,17-diene-3,16-dione inhibits the reaction [alisol B 23-acetate results in increased expression of ABCG8 protein]
|
https://ctdbase.org/detail.go?type=gene&acc=64241
|
||
|
ABCG8
|
Mus musculus (house mouse)
|
Triptonide results in increased expression of ABCG8 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=64241
|
||
|
ABCG8
|
Homo sapiens (human)
|
Methyleugenol results in decreased expression of ABCG8 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=64241
|
||
|
ABCG8
|
Xenopus tropicalis (tropical clawed frog)
|
Dimethyl phthalate affects the expression of ABCG8 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=64241
|
||
|
ABCG8
|
Mus musculus (house mouse)
|
Lithocholic acid results in decreased expression of ABCG8 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=64241
|
||
|
ABCG8
|
Mus musculus (house mouse)
|
Lithocholic acid results in increased expression of ABCG8 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=64241
|
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