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SCFBio, IIT Delhi Hauz Khas, New Delhi
MOLECULAR TARGET

ABCG8

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81

Interactions

Rattus norvegicus (Norway rat)

Organism

ABCG8

Gene Name

Compound Associations

S.No BIMP ID Organism Action References
1 BIMP091061 Rattus norvegicus (Norway rat) Ethinyl estradiol results in decreased expression of ABCG8 mRNA
2 BIMP091061 Rattus norvegicus (Norway rat) [ethinyl estradiol co-treated with cholic acids] affects the expression of ABCG8 mRNA
3 BIMP091061 Rattus norvegicus (Norway rat) Ethinyl estradiol results in decreased expression of ABCG8 mrna|esr1 protein promotes the reaction [ethinyl estradiol results in decreased expression of ABCG8 mrna]
4 BIMP091061 Rattus norvegicus (Norway rat) [ethinyl estradiol co-treated with diosgenin] results in decreased expression of ABCG8 mRNA
5 BIMP091061 Rattus norvegicus (Norway rat) Ethinyl estradiol results in decreased expression of ABCG8 mRNA
6 BIMP091061 Rattus norvegicus (Norway rat) [ethinyl estradiol results in decreased expression of ABCG8 mrna] which results in decreased secretion of cholesterol
7 BIMP091061 Rattus norvegicus (Norway rat) Ethinyl estradiol results in decreased expression of ABCG8 mRNA
8 BIMP090682 Rattus norvegicus (Norway rat) Spironolactone results in decreased expression of ABCG8 mRNA
9 BIMP090802 Rattus norvegicus (Norway rat) Dehydroepiandrosterone results in increased activity of [ABCG5 protein binds to ABCG8 protein]
10 BIMP089937 Rattus norvegicus (Norway rat) [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of ABCG8 mRNA
11 BIMP089937 Rattus norvegicus (Norway rat) Pirinixic acid results in decreased expression of ABCG8 mRNA
12 BIMP089937 Rattus norvegicus (Norway rat) Pirinixic acid results in increased expression of ABCG8 mRNA
13 BIMP089374 Rattus norvegicus (Norway rat) Triclosan affects the expression of ABCG8 mRNA
14 BIMP082880 Rattus norvegicus (Norway rat) Cyclosporine results in decreased expression of ABCG8 mRNA
15 BIMP082880 Rattus norvegicus (Norway rat) [glycochenodeoxycholic acid co-treated with deoxycholic acid co-treated with chenodeoxycholic acid co-treated with glycodeoxycholic acid co-treated with glycocholic acid co-treated with cyclosporine] results in decreased expression of ABCG8 mRNA
16 BIMP090535 Rattus norvegicus (Norway rat) Estradiol results in decreased expression of ABCG8 mRNA
17 BIMP090535 Rattus norvegicus (Norway rat) [bisphenol A co-treated with estradiol] results in increased expression of ABCG8 mRNA
18 BIMP090535 Rattus norvegicus (Norway rat) Estradiol affects the expression of ABCG8 mRNA
19 BIMP090535 Rattus norvegicus (Norway rat) [testosterone co-treated with estradiol] results in increased expression of ABCG8 mRNA
20 BIMP079193 Rattus norvegicus (Norway rat) Halofuginone results in decreased expression of ABCG8 mRNA
21 BIMP078712 Rattus norvegicus (Norway rat) Diethylstilbestrol results in increased expression of ABCG8 mRNA
22 BIMP082095 Rattus norvegicus (Norway rat) Quercetin results in decreased expression of ABCG8 mRNA
23 BIMP082208 Rattus norvegicus (Norway rat) [stigmasterol co-treated with oligomycins] results in decreased expression of ABCG8 mrna|stigmasterol results in decreased expression of ABCG8 mrna|[stigmasterol co-treated with rotenone] results in decreased expression of ABCG8 mRNA
24 BIMP088572 Rattus norvegicus (Norway rat) Trilinolenin results in decreased expression of ABCG8 mRNA
25 BIMP085911 Rattus norvegicus (Norway rat) Trilinolein results in decreased expression of ABCG8 mRNA
26 BIMP088673 Rattus norvegicus (Norway rat) Tetracycline results in decreased expression of ABCG8 mRNA
27 BIMP089279 Rattus norvegicus (Norway rat) Triolein results in decreased expression of ABCG8 mRNA
28 BIMP072264 Rattus norvegicus (Norway rat) Ursodeoxycholic acid results in increased expression of ABCG8 mRNA
29 BIMP072264 Rattus norvegicus (Norway rat) Ursodeoxycholic acid affects the expression of ABCG8 mRNA
30 BIMP072198 Rattus norvegicus (Norway rat) Valproic acid affects the methylation of ABCG8 gene
31 BIMP072198 Rattus norvegicus (Norway rat) Valproic acid results in decreased expression of ABCG8 mRNA
32 BIMP072198 Rattus norvegicus (Norway rat) Valproic acid results in decreased methylation of ABCG8 gene
33 BIMP072198 Rattus norvegicus (Norway rat) Valproic acid affects the expression of ABCG8 mRNA
34 BIMP072198 Rattus norvegicus (Norway rat) Valproic acid results in increased expression of ABCG8 mRNA
35 BIMP071289 Rattus norvegicus (Norway rat) Clofibrate inhibits the reaction [PPARA gene mutant form results in increased expression of ABCG8 mrna]
36 BIMP071289 Rattus norvegicus (Norway rat) Clofibrate results in decreased expression of ABCG8 mRNA
37 BIMP071185 Rattus norvegicus (Norway rat) [NR1H3 protein affects the susceptibility to fumonisin B1] which affects the expression of ABCG8 mrna|[nr1h2 protein affects the susceptibility to fumonisin B1] which affects the expression of ABCG8 mRNA
38 BIMP068482 Rattus norvegicus (Norway rat) Benzo(a)pyrene results in decreased expression of ABCG8 mRNA
39 BIMP068482 Rattus norvegicus (Norway rat) Benzo(a)pyrene results in decreased methylation of ABCG8 promoter
40 BIMP077135 Rattus norvegicus (Norway rat) [plant extracts co-treated with resveratrol] results in decreased expression of ABCG8 mRNA
41 BIMP073146 Rattus norvegicus (Norway rat) Indole-3-carbinol affects the expression of ABCG8 mRNA
42 BIMP073146 Rattus norvegicus (Norway rat) [indole-3-carbinol co-treated with diethylnitrosamine] results in increased expression of ABCG8 mRNA
43 BIMP072904 Rattus norvegicus (Norway rat) Zidovudine results in decreased expression of ABCG8 mRNA
44 BIMP026639 Rattus norvegicus (Norway rat) N-nitrosopyrrolidine results in decreased expression of ABCG8 mRNA
45 BIMP028660 Rattus norvegicus (Norway rat) 2,4,6-trimethyl-N-((3'-(methylsulfonyl)-4-biphenylyl)methyl)-N-((5-(trifluoromethyl)-2-furanyl)methyl)benzenesulfonamide inhibits the reaction [alisol B 23-acetate results in increased expression of ABCG8 mrna]|alisol B 23-acetate results in increased expression of ABCG8 mrna|2,4,6-trimethyl-N-((3'-(methylsulfonyl)-4-biphenylyl)methyl)-N-((5-(trifluoromethyl)-2-furanyl)methyl)benzenesulfonamide inhibits the reaction [alisol B 23-acetate results in increased expression of ABCG8 protein]
46 BIMP028660 Rattus norvegicus (Norway rat) Alisol B 23-acetate results in increased expression of ABCG8 protein
47 BIMP028660 Rattus norvegicus (Norway rat) Pregna-4,17-diene-3,16-dione inhibits the reaction [alisol B 23-acetate results in increased expression of ABCG8 protein]
48 BIMP036503 Rattus norvegicus (Norway rat) Schizandrin B inhibits the reaction [carbon tetrachloride results in decreased expression of ABCG8 mrna]
49 BIMP032534 Rattus norvegicus (Norway rat) [vancomycin co-treated with imipenem] affects the expression of ABCG8 mRNA
50 BIMP014566 Rattus norvegicus (Norway rat) ABCG8 protein affects the export of sterols
51 BIMP014566 Rattus norvegicus (Norway rat) ABCG8 protein affects the export of sterols
52 BIMP016143 Rattus norvegicus (Norway rat) Toluene affects the expression of ABCG8 mRNA
53 BIMP067854 Rattus norvegicus (Norway rat) Cholates promotes the reaction [ABCG8 protein results in increased secretion of cholesterol]|cholates results in increased expression of ABCG8 protein|cholates results in increased expression of ABCG8 mRNA
54 BIMP067854 Rattus norvegicus (Norway rat) Cholic acid results in increased expression of ABCG8 mRNA
55 BIMP067854 Rattus norvegicus (Norway rat) [NR1H4 protein mutant form inhibits the reaction [cholic acid results in increased phosphorylation of NR1H4 protein]] which results in decreased expression of ABCG8 mRNA
56 BIMP067942 Rattus norvegicus (Norway rat) [glycochenodeoxycholic acid co-treated with deoxycholic acid co-treated with chenodeoxycholic acid co-treated with glycodeoxycholic acid co-treated with glycocholic acid co-treated with tartrazine] results in decreased expression of ABCG8 mrna|[glycochenodeoxycholic acid co-treated with deoxycholic acid co-treated with chenodeoxycholic acid co-treated with glycodeoxycholic acid co-treated with glycocholic acid co-treated with atazanavir sulfate] results in decreased expression of ABCG8 mrna|[glycochenodeoxycholic acid co-treated with deoxycholic acid co-treated with chenodeoxycholic acid co-treated with glycodeoxycholic acid co-treated with glycocholic acid co-treated with 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt] results in decreased expression of ABCG8 mrna|[glycochenodeoxycholic acid co-treated with deoxycholic acid co-treated with chenodeoxycholic acid co-treated with glycodeoxycholic acid co-treated with glycocholic acid co-treated with nefazodone] results in decreased expression of ABCG8 mrna|[glycochenodeoxycholic acid co-treated with deoxycholic acid co-treated with chenodeoxycholic acid co-treated with glycodeoxycholic acid co-treated with glycocholic acid co-treated with cyclosporine] results in decreased expression of ABCG8 mrna|[glycochenodeoxycholic acid co-treated with deoxycholic acid co-treated with chenodeoxycholic acid co-treated with glycodeoxycholic acid co-treated with glycocholic acid co-treated with acetaminophen] results in decreased expression of ABCG8 mRNA
57 BIMP067942 Rattus norvegicus (Norway rat) Deoxycholic acid results in increased expression of ABCG8 mRNA
58 BIMP067942 Rattus norvegicus (Norway rat) SLCO1A1 protein affects the susceptibility to [deoxycholic acid results in increased expression of ABCG8 mrna]
59 BIMP068008 Rattus norvegicus (Norway rat) Aristolochic acid I results in increased expression of ABCG8 mRNA
60 BIMP064420 Rattus norvegicus (Norway rat) Aflatoxin B1 affects the expression of ABCG8 protein
61 BIMP064420 Rattus norvegicus (Norway rat) Aflatoxin B1 results in decreased expression of ABCG8 mrna|aflatoxin B1 results in decreased methylation of ABCG8 gene
62 BIMP064420 Rattus norvegicus (Norway rat) Aflatoxin B1 results in increased expression of ABCG8 mRNA
63 BIMP095782 Rattus norvegicus (Norway rat) Methyleugenol results in decreased expression of ABCG8 mRNA
64 BIMP095241 Rattus norvegicus (Norway rat) Ethanol results in decreased expression of ABCG8 mRNA
65 BIMP094130 Rattus norvegicus (Norway rat) Triptonide results in increased expression of ABCG8 mRNA
66 BIMP093430 Rattus norvegicus (Norway rat) Pregna-4,17-diene-3,16-dione inhibits the reaction [alisol B 23-acetate results in increased expression of ABCG8 protein]
67 BIMP105606 Rattus norvegicus (Norway rat) Diosgenin promotes the reaction [ABCG8 protein results in increased secretion of cholesterol]
68 BIMP105606 Rattus norvegicus (Norway rat) [diosgenin results in increased expression of ABCG8 mrna] which results in increased secretion of cholesterol|diosgenin results in increased expression of ABCG8 mRNA
69 BIMP105606 Rattus norvegicus (Norway rat) [ethinyl estradiol co-treated with diosgenin] results in decreased expression of ABCG8 mRNA
70 BIMP105476 Rattus norvegicus (Norway rat) Lithocholic acid results in decreased expression of ABCG8 mRNA
71 BIMP105476 Rattus norvegicus (Norway rat) Lithocholic acid results in increased expression of ABCG8 mRNA
72 BIMP101295 Rattus norvegicus (Norway rat) [APOE gene mutant form results in increased susceptibility to diethylhexyl phthalate] which results in decreased expression of ABCG8 protein
73 BIMP101295 Rattus norvegicus (Norway rat) [tetrachlorodibenzodioxin co-treated with bisphenol A co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with diethylhexyl phthalate] promotes the reaction [dietary fats results in increased expression of ABCG8 mrna]
74 BIMP101295 Rattus norvegicus (Norway rat) Diethylhexyl phthalate results in decreased expression of ABCG8 protein|diethylhexyl phthalate results in decreased expression of ABCG8 mRNA
75 BIMP101994 Rattus norvegicus (Norway rat) Dimethyl phthalate affects the expression of ABCG8 mRNA
76 BIMP094277 Rattus norvegicus (Norway rat) [tetrachlorodibenzodioxin co-treated with bisphenol A co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with diethylhexyl phthalate] promotes the reaction [dietary fats results in increased expression of ABCG8 mrna]
77 BIMP094277 Rattus norvegicus (Norway rat) Bisphenol A affects the expression of ABCG8 mRNA
78 BIMP094277 Rattus norvegicus (Norway rat) [bisphenol A co-treated with estradiol] results in increased expression of ABCG8 mRNA
79 BIMP094277 Rattus norvegicus (Norway rat) Bisphenol A results in decreased expression of ABCG8 mRNA
80 BIMP091430 Rattus norvegicus (Norway rat) Dimethylnitrosamine results in decreased expression of ABCG8 mRNA
81 BIMP091110 Rattus norvegicus (Norway rat) [testosterone co-treated with estradiol] results in increased expression of ABCG8 mRNA