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SCFBio, IIT Delhi Hauz Khas, New Delhi

Molecular Targets

Interactions between compounds and specific gene/protein targets.

Total Rows 750,454
Pages 30,019
BIMP_ID Target Name Gene Organism Action Source URL
ABCG2
Homo sapiens (human)
Lapatinib promotes the reaction [ABCG2 protein results in increased hydrolysis of adenosine triphosphate]|abcg2 protein results in increased hydrolysis of adenosine triphosphate
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Homo sapiens (human)
[adenosine triphosphate co-treated with ABCG2 protein] results in increased uptake of estrone sulfate|sulfasalazine inhibits the reaction [[adenosine triphosphate co-treated with ABCG2 protein] results in increased uptake of estrone sulfate]
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Homo sapiens (human)
Sulfasalazine promotes the reaction [ABCG2 protein results in increased hydrolysis of adenosine triphosphate]|vanadates inhibits the reaction [sulfasalazine promotes the reaction [ABCG2 protein results in increased hydrolysis of adenosine triphosphate]]|abcg2 protein results in increased hydrolysis of adenosine triphosphate
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Homo sapiens (human)
Luteolin affects the activity of ABCG2 protein
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Homo sapiens (human)
Quercetin results in increased expression of ABCG2 mrna|quercetin results in increased expression of ABCG2 protein|ahr protein promotes the reaction [quercetin results in increased expression of ABCG2 protein]
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Homo sapiens (human)
Quercetin affects the expression of ABCG2 mRNA
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Homo sapiens (human)
Quercetin results in decreased expression of ABCG2 mrna|quercetin results in decreased expression of ABCG2 protein
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Mus musculus (house mouse)
ABCG2 protein affects the export of quercetin metabolite|abcg2 protein affects the export of quercetin
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Homo sapiens (human)
https://www.dgidb.org/genes/hgnc:74
ABCG2
Mus musculus (house mouse)
Probenecid inhibits the reaction [potassium oxonate results in increased expression of ABCG2 protein]
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Homo sapiens (human)
Silymarin results in increased expression of ABCG2 protein|ahr protein promotes the reaction [silymarin results in increased expression of ABCG2 protein]
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Homo sapiens (human)
Benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [indolo(3,2-b)carbazole results in increased expression of ABCG2 mrna]
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Homo sapiens (human)
Hippuric acid inhibits the reaction [ABCG2 protein results in increased export of estrone sulfate]
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Homo sapiens (human)
Colforsin inhibits the reaction [anandamide inhibits the reaction [CREB1 protein modified form binds to ABCG2 promoter]]
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Homo sapiens (human)
Colforsin results in increased expression of ABCG2 mRNA
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Mus musculus (house mouse)
ABCG2 protein affects the export of hymecromone analog
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Homo sapiens (human)
Flavonoids results in decreased activity of ABCG2 protein
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Homo sapiens (human)
[glycochenodeoxycholic acid co-treated with deoxycholic acid co-treated with chenodeoxycholic acid co-treated with glycodeoxycholic acid co-treated with glycocholic acid co-treated with 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt] results in increased expression of ABCG2 mrna|[glycochenodeoxycholic acid co-treated with deoxycholic acid co-treated with chenodeoxycholic acid co-treated with glycodeoxycholic acid co-treated with glycocholic acid co-treated with atazanavir sulfate] results in increased expression of ABCG2 mrna|[glycochenodeoxycholic acid co-treated with deoxycholic acid co-treated with chenodeoxycholic acid co-treated with glycodeoxycholic acid co-treated with glycocholic acid co-treated with nefazodone] results in increased expression of ABCG2 mrna|[glycochenodeoxycholic acid co-treated with deoxycholic acid co-treated with chenodeoxycholic acid co-treated with glycodeoxycholic acid co-treated with glycocholic acid co-treated with tartrazine] results in decreased expression of ABCG2 mrna|[glycochenodeoxycholic acid co-treated with deoxycholic acid co-treated with chenodeoxycholic acid co-treated with glycodeoxycholic acid co-treated with glycocholic acid co-treated with cyclosporine] results in increased expression of ABCG2 mRNA
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Homo sapiens (human)
[docetaxel results in decreased susceptibility to docetaxel] which results in decreased expression of ABCG2 mRNA
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Homo sapiens (human)
https://www.dgidb.org/genes/hgnc:74
ABCG2
Oryctolagus cuniculus (rabbit)
Chlormequat inhibits the reaction [ABCG2 protein results in increased secretion of bisbenzimide ethoxide trihydrochloride]
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Homo sapiens (human)
AHR protein promotes the reaction [2-tert-butylhydroquinone results in increased expression of ABCG2 protein]|2-tert-butylhydroquinone results in increased expression of ABCG2 mrna|2-tert-butylhydroquinone results in increased expression of ABCG2 protein
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Mus musculus (house mouse)
Allopurinol inhibits the reaction [[oxonic acid analog co-treated with hypoxanthine] results in decreased expression of ABCG2 mrna]|allopurinol inhibits the reaction [[oxonic acid analog co-treated with hypoxanthine] results in decreased expression of ABCG2 protein]
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Mus musculus (house mouse)
Allopurinol inhibits the reaction [potassium oxonate results in increased expression of ABCG2 protein]
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Homo sapiens (human)
[3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester results in decreased activity of ABCG2 protein] inhibits the reaction [folic acid deficiency results in decreased susceptibility to mitoxantrone]|[folic acid deficiency results in increased expression of ABCG2 protein] which results in decreased susceptibility to mitoxantrone|folic acid deficiency results in increased expression of ABCG2 protein|folic acid deficiency results in increased expression of ABCG2 mRNA
https://ctdbase.org/detail.go?type=gene&acc=9429
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