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SCFBio, IIT Delhi Hauz Khas, New Delhi

Molecular Targets

Interactions between compounds and specific gene/protein targets.

Total Rows 750,454
Pages 30,019
BIMP_ID Target Name Gene Organism Action Source URL
ABCG2
Homo sapiens (human)
ABCG2 protein affects the transport of folic acid|protons promotes the reaction [ABCG2 protein results in increased transport of folic acid]
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Homo sapiens (human)
Folic acid affects the localization of and affects the expression of ABCG2 protein
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Mus musculus (house mouse)
[methionine deficiency co-treated with choline deficiency co-treated with folic acid deficiency] results in increased methylation of ABCG2 gene
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Rattus norvegicus (Norway rat)
Folic acid results in decreased expression of ABCG2 protein|folic acid results in decreased expression of ABCG2 mRNA
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Homo sapiens (human)
https://www.dgidb.org/genes/hgnc:74
ABCG2
Mus musculus (house mouse)
[vancomycin co-treated with neomycin co-treated with ampicillin co-treated with metronidazole co-treated with amphotericin B] results in increased expression of ABCG2 mrna|[sodium selenite results in increased abundance of selenium] inhibits the reaction [[vancomycin co-treated with neomycin co-treated with ampicillin co-treated with metronidazole co-treated with amphotericin B] results in increased expression of ABCG2 mrna]
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Homo sapiens (human)
Naproxen affects the expression of ABCG2 protein|naproxen affects the activity of ABCG2 protein
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Rattus norvegicus (Norway rat)
Schizandrin B inhibits the reaction [carbon tetrachloride results in decreased expression of ABCG2 mrna]
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Homo sapiens (human)
Aflatoxin B1 affects the expression of ABCG2 protein
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Homo sapiens (human)
[aflatoxin B1 co-treated with finrozole] results in increased expression of ABCG2 mrna|[aflatoxin B1 co-treated with finrozole] results in decreased expression of ABCG2 protein|aflatoxin B1 results in decreased expression of ABCG2 protein|aflatoxin B1 results in increased expression of ABCG2 mRNA
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Rattus norvegicus (Norway rat)
Tadalafil inhibits the reaction [[aflatoxin B1 co-treated with ethanol] results in increased expression of ABCG2 mrna]|[aflatoxin B1 co-treated with ethanol] results in increased expression of ABCG2 mrna|sildenafil citrate inhibits the reaction [[aflatoxin B1 co-treated with ethanol] results in increased expression of ABCG2 mrna]
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Rattus norvegicus (Norway rat)
Aflatoxin B1 results in increased expression of ABCG2 mRNA
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Homo sapiens (human)
https://www.dgidb.org/genes/hgnc:74
ABCG2
Mus musculus (house mouse)
[perfluorooctane sulfonic acid co-treated with cellulose] results in increased expression of ABCG2 mRNA
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Homo sapiens (human)
Fulvestrant affects the reaction [4-nonylphenol results in decreased expression of ABCG2 protein]|4-nonylphenol results in decreased expression of ABCG2 protein
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Homo sapiens (human)
Abrine results in decreased expression of ABCG2 mRNA
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Homo sapiens (human)
[NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ABCG2 mrna|[nog protein co-treated with phenylmercuric acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ABCG2 mrna|[nog protein co-treated with valproic acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ABCG2 mrna|[nog protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ABCG2 mrna|[nog protein co-treated with panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ABCG2 mrna|[nog protein co-treated with p-chloromercuribenzoic acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ABCG2 mRNA
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Homo sapiens (human)
Protoapigenone analog results in decreased expression of ABCG2 protein
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Homo sapiens (human)
Alpha-naphthoflavone results in decreased activity of ABCG2 protein
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Mus musculus (house mouse)
[oxonic acid analog co-treated with hypoxanthine] results in decreased expression of ABCG2 mrna|polysaccharides inhibits the reaction [[oxonic acid analog co-treated with hypoxanthine] results in decreased expression of ABCG2 mrna]|allopurinol inhibits the reaction [[oxonic acid analog co-treated with hypoxanthine] results in decreased expression of ABCG2 mrna]|polysaccharides inhibits the reaction [[oxonic acid analog co-treated with hypoxanthine] results in decreased expression of ABCG2 protein]|allopurinol inhibits the reaction [[oxonic acid analog co-treated with hypoxanthine] results in decreased expression of ABCG2 protein]|[oxonic acid analog co-treated with hypoxanthine] results in decreased expression of ABCG2 protein
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Homo sapiens (human)
Methotrexate inhibits the reaction [ABCG2 protein results in increased export of glutathione]|abcg2 protein results in increased export of glutathione|2',5'-dihydroxychalcone promotes the reaction [ABCG2 protein results in increased export of glutathione]
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Mus musculus (house mouse)
Oleanolic acid results in increased expression of ABCG2 mRNA
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Rattus norvegicus (Norway rat)
Toluene affects the expression of ABCG2 mRNA
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Rattus norvegicus (Norway rat)
Triptolide results in increased expression of ABCG2 protein
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Homo sapiens (human)
Indican inhibits the reaction [ABCG2 protein results in increased export of estrone sulfate]
https://ctdbase.org/detail.go?type=gene&acc=9429
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