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SCFBio, IIT Delhi Hauz Khas, New Delhi

Molecular Targets

Interactions between compounds and specific gene/protein targets.

Total Rows 750,454
Pages 30,019
BIMP_ID Target Name Gene Organism Action Source URL
ABCG2
Rattus norvegicus (Norway rat)
Ethinyl estradiol results in decreased expression of ABCG2 mRNA
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Rattus norvegicus (Norway rat)
Ethinyl estradiol results in decreased expression of and results in decreased activity of ABCG2 protein|fulvestrant inhibits the reaction [ethinyl estradiol results in decreased expression of ABCG2 protein]
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Xenopus tropicalis (tropical clawed frog)
Ethinyl estradiol results in increased expression of ABCG2 mRNA
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Homo sapiens (human)
ABCG2 affects the susceptibility to irinotecan
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Homo sapiens (human)
ABCG2 protein affects the metabolism of irinotecan|abcg2 gene polymorphism affects the susceptibility to and affects the metabolism of irinotecan
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Homo sapiens (human)
ABCG2 mRNA results in increased susceptibility to irinotecan
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Homo sapiens (human)
ABCG2 protein affects the export of irinotecan
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Homo sapiens (human)
ABCG2 protein results in decreased susceptibility to irinotecan
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Homo sapiens (human)
ABCG2 protein results in increased susceptibility to irinotecan
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Homo sapiens (human)
ABCG2 results in decreased susceptibility to irinotecan|reserpine inhibits the reaction [ABCG2 protein results in increased transport of irinotecan]|abcg2 protein results in increased transport of irinotecan
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Homo sapiens (human)
Porphyrins inhibits the reaction [ABCG2 protein results in decreased susceptibility to irinotecan]
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Mus musculus (house mouse)
ABCG2 protein affects the metabolism of irinotecan|bis(4-nitrophenyl)phosphate inhibits the reaction [ABCG2 protein affects the metabolism of irinotecan]|everolimus inhibits the reaction [ABCG2 protein affects the metabolism of irinotecan]
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Homo sapiens (human)
ABCG2 protein results in increased export of irinotecan
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Homo sapiens (human)
https://www.dgidb.org/genes/hgnc:74
ABCG2
Homo sapiens (human)
[pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of ABCG2 mRNA
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Mus musculus (house mouse)
Pirinixic acid results in increased expression of ABCG2 mRNA
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Mus musculus (house mouse)
PPARA protein promotes the reaction [pirinixic acid results in increased expression of ABCG2 mrna]
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Homo sapiens (human)
ABCG2 protein affects the reaction [mifepristone results in decreased transport of pheophorbide a]
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Homo sapiens (human)
Triclosan results in increased expression of ABCG2 mRNA
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Mus musculus (house mouse)
Tetracycline results in decreased expression of ABCG2 mRNA
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Homo sapiens (human)
ABCG2 protein affects the transport of estrogens
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Homo sapiens (human)
Estrone results in increased expression of ABCG2 mRNA
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Homo sapiens (human)
Reserpine inhibits the reaction [ABCG2 protein results in increased transport of irinotecan]|reserpine inhibits the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Homo sapiens (human)
https://www.dgidb.org/genes/hgnc:74
ABCG2
Rattus norvegicus (Norway rat)
[diethyl phthalate co-treated with diethylhexyl phthalate co-treated with dibutyl phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of ABCG2 mRNA
https://ctdbase.org/detail.go?type=gene&acc=9429
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