Molecular Targets : Dataset Browser

BIMP_ID	Target Name	Gene	Organism	Action	Source URL
BIMP082465	ABCG2	ABCG2	Homo sapiens (human)	Chrysin inhibits the reaction [ABCG2 protein results in increased secretion of mitoxantrone]\|chrysin inhibits the reaction [ABCG2 protein results in increased transport of nitrofurantoin]\|chrysin results in decreased activity of ABCG2 protein	https://ctdbase.org/detail.go?type=gene&acc=9429
BIMP082465	ABCG2	ABCG2	Homo sapiens (human)	Chrysin results in increased expression of ABCG2 protein\|chrysin results in decreased activity of ABCG2 protein\|[chrysin results in decreased activity of ABCG2 protein] which results in decreased export of topotecan	https://ctdbase.org/detail.go?type=gene&acc=9429
BIMP082465	ABCG2	ABCG2	Homo sapiens (human)	Chrysin results in decreased expression of ABCG2 mRNA	https://ctdbase.org/detail.go?type=gene&acc=9429
BIMP082465	ABCG2	ABCG2	Homo sapiens (human)	Chrysin results in increased expression of ABCG2 mRNA	https://ctdbase.org/detail.go?type=gene&acc=9429
BIMP082465	ABCG2	ABCG2	Rattus norvegicus (Norway rat)	Chrysin inhibits the reaction [ABCG2 protein affects the transport of nitrofurantoin]	https://ctdbase.org/detail.go?type=gene&acc=9429
BIMP090535	ABCG2	ABCG2	Homo sapiens (human)	ESR1 protein promotes the reaction [[estradiol co-treated with testosterone] results in increased expression of ABCG2 mrna]\|estradiol affects the expression of ABCG2 protein\|flutamide inhibits the reaction [[estradiol co-treated with testosterone] results in increased expression of ABCG2 mrna]\|[estradiol co-treated with testosterone] results in increased expression of ABCG2 protein\|flutamide inhibits the reaction [[estradiol co-treated with testosterone] results in increased expression of ABCG2 protein]\|fulvestrant inhibits the reaction [[estradiol co-treated with testosterone] results in increased expression of ABCG2 protein]\|[estradiol co-treated with testosterone] results in increased expression of ABCG2 mrna\|fulvestrant inhibits the reaction [[estradiol co-treated with testosterone] results in increased expression of ABCG2 mrna]	https://ctdbase.org/detail.go?type=gene&acc=9429
BIMP090535	ABCG2	ABCG2	Homo sapiens (human)	[estradiol binds to ESR1 protein] which results in decreased expression of abcg2\|estradiol results in decreased expression of abcg2\|tamoxifen inhibits the reaction [estradiol results in decreased expression of ABCG2]	https://ctdbase.org/detail.go?type=gene&acc=9429
BIMP090535	ABCG2	ABCG2	Homo sapiens (human)	[estradiol co-treated with tetrachlorodibenzodioxin] results in increased expression of ABCG2 mRNA	https://ctdbase.org/detail.go?type=gene&acc=9429
BIMP090535	ABCG2	ABCG2	Homo sapiens (human)	Estradiol inhibits the reaction [ABCG2 protein affects the transport of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine]	https://ctdbase.org/detail.go?type=gene&acc=9429
BIMP090535	ABCG2	ABCG2	Homo sapiens (human)	Estradiol inhibits the reaction [ABCG2 protein results in increased uptake of estrone sulfate]	https://ctdbase.org/detail.go?type=gene&acc=9429
BIMP090535	ABCG2	ABCG2	Homo sapiens (human)	Estradiol results in decreased activity of ABCG2 protein	https://ctdbase.org/detail.go?type=gene&acc=9429
BIMP090535	ABCG2	ABCG2	Homo sapiens (human)	[estradiol results in decreased activity of ABCG2 protein] which results in increased uptake of abacavir	https://ctdbase.org/detail.go?type=gene&acc=9429
BIMP090535	ABCG2	ABCG2	Homo sapiens (human)	Estradiol results in decreased expression of ABCG2 protein\|fulvestrant affects the reaction [estradiol results in decreased expression of ABCG2 protein]	https://ctdbase.org/detail.go?type=gene&acc=9429
BIMP090535	ABCG2	ABCG2	Homo sapiens (human)	Estradiol results in increased expression of ABCG2 mRNA	https://ctdbase.org/detail.go?type=gene&acc=9429
BIMP090535	ABCG2	ABCG2	Homo sapiens (human)	Progesterone inhibits the reaction [estradiol results in increased expression of abcg2]\|estradiol results in increased expression of ABCG2 protein	https://ctdbase.org/detail.go?type=gene&acc=9429
BIMP090535	ABCG2	ABCG2	Mus musculus (house mouse)	Estradiol results in decreased expression of ABCG2 protein	https://ctdbase.org/detail.go?type=gene&acc=9429
BIMP090534	ABCG2	ABCG2	Homo sapiens (human)	Estriol results in increased expression of ABCG2 mRNA	https://ctdbase.org/detail.go?type=gene&acc=9429
BIMP090534	ABCG2	ABCG2	Homo sapiens (human)	Fulvestrant inhibits the reaction [estriol results in increased expression of ABCG2 protein]\|fulvestrant inhibits the reaction [estriol results in increased expression of ABCG2 mrna]\|estriol results in increased expression of ABCG2 protein	https://ctdbase.org/detail.go?type=gene&acc=9429
BIMP090429	ABCG2	ABCG2	Homo sapiens (human)	Dexamethasone inhibits the reaction [ABCG2 protein affects the transport of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine]	https://ctdbase.org/detail.go?type=gene&acc=9429
BIMP090429	ABCG2	ABCG2	Rattus norvegicus (Norway rat)	Dexamethasone results in decreased expression of ABCG2 mRNA	https://ctdbase.org/detail.go?type=gene&acc=9429
BIMP091430	ABCG2	ABCG2	Homo sapiens (human)	Dimethylnitrosamine results in increased expression of ABCG2 mRNA	https://ctdbase.org/detail.go?type=gene&acc=9429
BIMP091300	ABCG2	ABCG2	Mus musculus (house mouse)	ABCG2 gene mutant form results in increased susceptibility to irinotecan	https://ctdbase.org/detail.go?type=gene&acc=9429
BIMP091110	ABCG2	ABCG2	Homo sapiens (human)	ESR1 protein promotes the reaction [[estradiol co-treated with testosterone] results in increased expression of ABCG2 mrna]\|flutamide inhibits the reaction [[estradiol co-treated with testosterone] results in increased expression of ABCG2 mrna]\|[estradiol co-treated with testosterone] results in increased expression of ABCG2 protein\|flutamide inhibits the reaction [[estradiol co-treated with testosterone] results in increased expression of ABCG2 protein]\|fulvestrant inhibits the reaction [[estradiol co-treated with testosterone] results in increased expression of ABCG2 protein]\|[estradiol co-treated with testosterone] results in increased expression of ABCG2 mrna\|fulvestrant inhibits the reaction [[estradiol co-treated with testosterone] results in increased expression of ABCG2 mrna]	https://ctdbase.org/detail.go?type=gene&acc=9429
BIMP091110	ABCG2	ABCG2	Homo sapiens (human)	Testosterone results in decreased activity of ABCG2 protein\|testosterone inhibits the reaction [ABCG2 protein results in increased uptake of estrone sulfate]	https://ctdbase.org/detail.go?type=gene&acc=9429
BIMP091110	ABCG2	ABCG2	Mus musculus (house mouse)	Testosterone results in increased expression of ABCG2 mRNA	https://ctdbase.org/detail.go?type=gene&acc=9429

BIMP082465

ABCG2

Homo sapiens (human)

Chrysin inhibits the reaction [ABCG2 protein results in increased secretion of mitoxantrone]|chrysin inhibits the reaction [ABCG2 protein results in increased transport of nitrofurantoin]|chrysin results in decreased activity of ABCG2 protein