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Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
ABCG2
|
Homo sapiens (human)
|
Inhibition
|
https://guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=792
|
||
|
ABCG2
|
Homo sapiens (human)
|
|
https://www.dgidb.org/genes/hgnc:74
|
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|
ABCG2
|
Rattus norvegicus (Norway rat)
|
[morphine co-treated with naloxone] results in increased expression of ABCG2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Homo sapiens (human)
|
|
https://www.dgidb.org/genes/hgnc:74
|
||
|
ABCG2
|
Mus musculus (house mouse)
|
Fenretinide results in increased expression of ABCG2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Homo sapiens (human)
|
5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one results in decreased activity of ABCG2 protein|5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one inhibits the reaction [ABCG2 protein results in increased uptake of lucifer yellow]
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Rattus norvegicus (Norway rat)
|
[3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester results in decreased activity of ABCG2 protein] which results in decreased secretion of diferuloylputrescine metabolite
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Rattus norvegicus (Norway rat)
|
[morphine co-treated with naloxone] results in increased expression of ABCG2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Homo sapiens (human)
|
|
https://www.dgidb.org/genes/hgnc:74
|
||
|
ABCG2
|
Mus musculus (house mouse)
|
[vancomycin co-treated with neomycin co-treated with ampicillin co-treated with metronidazole co-treated with amphotericin B] results in increased expression of ABCG2 mrna|[sodium selenite results in increased abundance of selenium] inhibits the reaction [[vancomycin co-treated with neomycin co-treated with ampicillin co-treated with metronidazole co-treated with amphotericin B] results in increased expression of ABCG2 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Homo sapiens (human)
|
Genistein inhibits the reaction [ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride]|genistein results in decreased expression of ABCG2 protein|genistein inhibits the reaction [ABCG2 protein results in increased export of glyburide]|genistein promotes the reaction [ABCG2 protein polymorphism results in decreased export of bisbenzimide ethoxide trihydrochloride]|genistein results in decreased expression of ABCG2 mrna|genistein promotes the reaction [ABCG2 protein polymorphism results in decreased export of glyburide]|fulvestrant inhibits the reaction [genistein results in decreased expression of ABCG2 protein]
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Ovis aries (sheep)
|
[genistein co-treated with daidzein] inhibits the reaction [ABCG2 protein results in increased transport of nitrofurantoin]
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Rattus norvegicus (Norway rat)
|
Genistein results in increased expression of ABCG2 mrna|ketoconazole inhibits the reaction [genistein results in increased expression of ABCG2 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Homo sapiens (human)
|
Tectochrysin results in decreased activity of ABCG2 protein
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Homo sapiens (human)
|
Anandamide inhibits the reaction [CREB1 protein modified form binds to ABCG2 promoter]|iodopravadoline inhibits the reaction [anandamide results in decreased expression of ABCG2 mrna]|8-bromo cyclic adenosine monophosphate inhibits the reaction [anandamide results in decreased expression of ABCG2 mrna]|anandamide results in decreased expression of ABCG2 protein|colforsin inhibits the reaction [anandamide inhibits the reaction [CREB1 protein modified form binds to ABCG2 promoter]]|anandamide results in decreased expression of ABCG2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Homo sapiens (human)
|
Anandamide affects the reaction [O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate affects the expression of ABCG2 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Mus musculus (house mouse)
|
Pterostilbene inhibits the reaction [potassium oxonate results in increased expression of ABCG2 protein]
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Homo sapiens (human)
|
|
https://www.dgidb.org/genes/hgnc:74
|
||
|
ABCG2
|
Mus musculus (house mouse)
|
ABCG2 protein affects the transport of daidzein
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Ovis aries (sheep)
|
[genistein co-treated with daidzein] inhibits the reaction [ABCG2 protein results in increased transport of nitrofurantoin]
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Mus musculus (house mouse)
|
Polydatin inhibits the reaction [potassium oxonate results in increased expression of ABCG2 protein]
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Canis lupus familiaris (dog)
|
ABCG2 protein results in increased transport of zearalenone
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Homo sapiens (human)
|
Zearalenone results in increased expression of ABCG2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Rattus norvegicus (Norway rat)
|
Zearalenone results in decreased expression of ABCG2 mrna|zearalenone results in decreased expression of ABCG2 protein
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Rattus norvegicus (Norway rat)
|
Zearalenone results in increased expression of ABCG2 protein|zearalenone results in increased expression of ABCG2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
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