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SCFBio, IIT Delhi Hauz Khas, New Delhi

Molecular Targets

Interactions between compounds and specific gene/protein targets.

Total Rows 750,454
Pages 30,019
BIMP_ID Target Name Gene Organism Action Source URL
ABCG2
Homo sapiens (human)
Porphyrins results in decreased activity of ABCG2 protein|porphyrins inhibits the reaction [ABCG2 protein results in increased export of mitoxantrone]|porphyrins inhibits the reaction [ABCG2 protein results in decreased susceptibility to irinotecan]|porphyrins inhibits the reaction [ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride]
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Rattus norvegicus (Norway rat)
[diethyl phthalate co-treated with diethylhexyl phthalate co-treated with dibutyl phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of ABCG2 mRNA
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Rattus norvegicus (Norway rat)
[diethyl phthalate co-treated with diethylhexyl phthalate co-treated with dibutyl phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of ABCG2 mRNA
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Homo sapiens (human)
Methylprednisolone inhibits the reaction [ABCG2 protein affects the transport of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine]
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Homo sapiens (human)
Zoledronic acid results in increased expression of ABCG2 mRNA
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Homo sapiens (human)
https://www.dgidb.org/genes/hgnc:74
ABCG2
Homo sapiens (human)
Epigallocatechin gallate results in decreased activity of ABCG2 protein
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Homo sapiens (human)
Epigallocatechin gallate results in increased expression of ABCG2 mRNA
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Mus musculus (house mouse)
Mulberroside A inhibits the reaction [potassium oxonate results in increased expression of ABCG2 protein]
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Homo sapiens (human)
Ginkgo biloba extract results in increased expression of ABCG2 mRNA alternative form
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Homo sapiens (human)
Rosiglitazone results in increased expression of ABCG2 protein|rosiglitazone inhibits the reaction [T 0070907 results in decreased expression of ABCG2 mrna]|rosiglitazone results in increased expression of ABCG2 mRNA
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Ovis aries (sheep)
Isoflavones inhibits the reaction [ABCG2 protein results in increased transport of nitrofurantoin]
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Bos taurus (cattle)
Prochloraz results in increased expression of ABCG2 mrna|prochloraz results in increased expression of ABCG2 protein
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Capra hircus (goat)
Salicylamide inhibits the reaction [prochloraz promotes the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]]|2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [prochloraz promotes the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]]|3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [prochloraz results in increased activity of ABCG2 protein]|prochloraz results in increased expression of ABCG2 mrna|3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [prochloraz promotes the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]]|2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [prochloraz results in increased expression of ABCG2 mrna]|salicylamide inhibits the reaction [prochloraz results in increased expression of ABCG2 mrna]|prochloraz results in increased activity of ABCG2 protein|2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [prochloraz results in increased activity of ABCG2 protein]|prochloraz promotes the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]|salicylamide inhibits the reaction [prochloraz results in increased activity of ABCG2 protein]
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Mus musculus (house mouse)
Prochloraz results in decreased expression of ABCG2 mRNA
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Mus musculus (house mouse)
Dichloroacetic acid results in increased expression of ABCG2 mRNA
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Homo sapiens (human)
[paclitaxel results in decreased expression of ABCG2] which results in decreased susceptibility to vincristine
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Homo sapiens (human)
[vincristine results in decreased susceptibility to vincristine] which results in increased expression of ABCG2 mRNA
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Homo sapiens (human)
Cyclosporine affects the expression of ABCG2 mRNA
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Homo sapiens (human)
Cyclosporine inhibits the reaction [ABCG2 protein results in increased export of mitoxantrone]
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Homo sapiens (human)
Cyclosporine inhibits the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Homo sapiens (human)
Cyclosporine results in decreased activity of ABCG2 protein
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Homo sapiens (human)
Cyclosporine results in increased expression of ABCG2 mRNA
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Homo sapiens (human)
[glycochenodeoxycholic acid co-treated with deoxycholic acid co-treated with chenodeoxycholic acid co-treated with glycodeoxycholic acid co-treated with glycocholic acid co-treated with cyclosporine] results in increased expression of ABCG2 mRNA
https://ctdbase.org/detail.go?type=gene&acc=9429
ABCG2
Mus musculus (house mouse)
Cyclosporine results in decreased expression of ABCG2 mRNA
https://ctdbase.org/detail.go?type=gene&acc=9429
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