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Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
ABCG2
|
Homo sapiens (human)
|
Protons promotes the reaction [ABCG2 protein results in increased export of resveratrol]|abcg2 protein affects the transport of resveratrol|elacridar inhibits the reaction [ABCG2 protein affects the transport of resveratrol]|elacridar inhibits the reaction [protons promotes the reaction [ABCG2 protein results in increased export of resveratrol]]
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Homo sapiens (human)
|
ABCG2 protein results in increased transport of resveratrol metabolite|resveratrol analog inhibits the reaction [ABCG2 protein results in increased transport of methotrexate]
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Homo sapiens (human)
|
AHR protein promotes the reaction [resveratrol results in increased expression of ABCG2 protein]|resveratrol results in increased expression of ABCG2 protein
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Homo sapiens (human)
|
Resveratrol results in decreased expression of ABCG2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Homo sapiens (human)
|
Resveratrol results in decreased expression of ABCG2 mRNA alternative form
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Homo sapiens (human)
|
Resveratrol results in increased expression of ABCG2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Mus musculus (house mouse)
|
Resveratrol inhibits the reaction [potassium oxonate results in increased expression of ABCG2 protein]
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Homo sapiens (human)
|
|
https://www.dgidb.org/genes/hgnc:74
|
||
|
ABCG2
|
Mus musculus (house mouse)
|
Dibutyl phthalate results in increased expression of ABCG2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Rattus norvegicus (Norway rat)
|
[diethyl phthalate co-treated with diethylhexyl phthalate co-treated with dibutyl phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of ABCG2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Mus musculus (house mouse)
|
[clofibrate co-treated with acetaminophen] affects the expression of ABCG2 mrna|ppara affects the reaction [[clofibrate co-treated with acetaminophen] affects the expression of ABCG2 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Mus musculus (house mouse)
|
Clofibrate results in increased expression of ABCG2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Mus musculus (house mouse)
|
Clofibrate results in increased expression of ABCG2 protein|ppara promotes the reaction [clofibrate results in increased expression of ABCG2 mrna]|ppara promotes the reaction [clofibrate results in increased expression of ABCG2 protein]
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Mus musculus (house mouse)
|
[methionine deficiency co-treated with choline deficiency co-treated with folic acid deficiency] results in increased methylation of ABCG2 gene
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Rattus norvegicus (Norway rat)
|
[methionine deficiency co-treated with choline deficiency] results in increased expression of ABCG2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Rattus norvegicus (Norway rat)
|
[methionine deficiency co-treated with choline deficiency] results in increased expression of ABCG2 protein
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Homo sapiens (human)
|
|
https://www.dgidb.org/genes/hgnc:74
|
||
|
ABCG2
|
Homo sapiens (human)
|
Enasidenib inhibits the reaction [ABCG2 protein results in decreased susceptibility to daunorubicin]|[enasidenib inhibits the reaction [ABCG2 protein results in increased export of daunorubicin]] which results in increased susceptibility to daunorubicin|abcg2 protein results in decreased susceptibility to daunorubicin|abcg2 protein results in increased export of daunorubicin|enasidenib inhibits the reaction [ABCG2 protein results in increased export of daunorubicin]|3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein results in increased export of daunorubicin]
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Homo sapiens (human)
|
Dactinomycin inhibits the reaction [daunorubicin results in increased expression of ABCG2 mrna]|daunorubicin results in increased expression of ABCG2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Homo sapiens (human)
|
Digoxin results in decreased activity of ABCG2 protein
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Homo sapiens (human)
|
Ciprofloxacin results in increased expression of ABCG2 protein
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Rattus norvegicus (Norway rat)
|
Amphetamine results in increased expression of ABCG2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Homo sapiens (human)
|
ABCG2 protein affects the export of estrone sulfate
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Homo sapiens (human)
|
ABCG2 protein affects the transport of estrone sulfate
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Homo sapiens (human)
|
Hippuric acid inhibits the reaction [ABCG2 protein results in increased export of estrone sulfate]|indican inhibits the reaction [ABCG2 protein results in increased export of estrone sulfate]|abcg2 protein results in increased export of estrone sulfate|kynurenic acid inhibits the reaction [ABCG2 protein results in increased export of estrone sulfate]
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
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