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Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
ABCG2
|
Homo sapiens (human)
|
ABCG2 protein results in increased uptake of estrone sulfate
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Homo sapiens (human)
|
[adenosine triphosphate co-treated with ABCG2 protein] results in increased uptake of estrone sulfate|sulfasalazine inhibits the reaction [[adenosine triphosphate co-treated with ABCG2 protein] results in increased uptake of estrone sulfate]
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Homo sapiens (human)
|
Estradiol inhibits the reaction [ABCG2 protein results in increased uptake of estrone sulfate]|progesterone inhibits the reaction [ABCG2 protein results in increased uptake of estrone sulfate]|androstenedione inhibits the reaction [ABCG2 protein results in increased uptake of estrone sulfate]|testosterone inhibits the reaction [ABCG2 protein results in increased uptake of estrone sulfate]
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Homo sapiens (human)
|
Risperidone inhibits the reaction [ABCG2 protein results in increased uptake of estrone sulfate]
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Homo sapiens (human)
|
Mitragynine affects the activity of ABCG2 protein
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Homo sapiens (human)
|
ABCG2 protein results in increased transport of notoginsenoside R1
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Homo sapiens (human)
|
ABCG2 protein results in decreased transport of ochratoxin A|ABCG2 protein affects the susceptibility to ochratoxin A|ABCG2 protein affects the transport of ochratoxin A|ABCG2 protein results in decreased susceptibility to ochratoxin A
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Mus musculus (house mouse)
|
ABCG2 protein results in increased transport of ochratoxin A
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Rattus norvegicus (Norway rat)
|
Ochratoxin A results in decreased expression of ABCG2 mrna|ochratoxin A results in increased expression of ABCG2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Canis lupus familiaris (dog)
|
[3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester results in decreased activity of ABCG2 protein] which results in decreased transport of hypaconitine|abcg2 protein results in increased transport of hypaconitine
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Mus musculus (house mouse)
|
ABCG2 protein affects the susceptibility to hypaconitine
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Homo sapiens (human)
|
ABCG2 protein results in increased transport of ginsenoside re
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Mus musculus (house mouse)
|
Isoproterenol results in increased expression of ABCG2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Homo sapiens (human)
|
Methoxsalen results in increased expression of ABCG2 mrna|[methoxsalen results in decreased activity of ABCG2 protein] which results in decreased export of and results in increased abundance of mitoxantrone|novobiocin inhibits the reaction [[methoxsalen results in decreased activity of ABCG2 protein] which results in decreased export of and results in increased abundance of mitoxantrone]|novobiocin inhibits the reaction [methoxsalen results in decreased activity of ABCG2 protein]|methoxsalen results in decreased activity of ABCG2 protein
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Homo sapiens (human)
|
ABCG2 protein affects the susceptibility to [fluorouracil co-treated with epirubicin co-treated with cyclophosphamide]
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Homo sapiens (human)
|
ABCG2 protein results in decreased susceptibility to epirubicin
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Homo sapiens (human)
|
Mitotane results in increased expression of ABCG2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Homo sapiens (human)
|
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ERBB2 results in increased expression of ABCG2 protein]|2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ERBB2 results in increased expression of ABCG2 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Homo sapiens (human)
|
Kynurenic acid inhibits the reaction [ABCG2 protein results in increased export of estrone sulfate]
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Homo sapiens (human)
|
Vitamin K 3 affects the expression of ABCG2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Homo sapiens (human)
|
Permethrin results in decreased activity of ABCG2 protein
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Mus musculus (house mouse)
|
Permethrin results in increased expression of ABCG2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Homo sapiens (human)
|
Curcumin results in increased expression of ABCG2 protein|ahr protein promotes the reaction [curcumin results in increased expression of ABCG2 protein]
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Homo sapiens (human)
|
Curcumin results in decreased expression of ABCG2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Homo sapiens (human)
|
|
https://www.dgidb.org/genes/hgnc:74
|
No matching records found on this page.