SCFBio, IIT Delhi
Hauz Khas, New Delhi
BIMP
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SCFBio, IIT Delhi
Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
ABCG2
|
Homo sapiens (human)
|
Zidovudine results in increased expression of ABCG2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Mus musculus (house mouse)
|
3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein results in decreased export of zidovudine]|elacridar inhibits the reaction [ABCG2 protein results in decreased export of zidovudine]|abcg2 protein results in decreased export of zidovudine
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Mus musculus (house mouse)
|
Elacridar inhibits the reaction [ABCG2 protein results in increased export of zidovudine]|abcg2 protein results in increased export of zidovudine|pluronic block copolymer p85 inhibits the reaction [ABCG2 protein results in increased export of zidovudine]|nelfinavir inhibits the reaction [ABCG2 protein results in increased export of zidovudine]|3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein results in increased export of zidovudine]
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Rattus norvegicus (Norway rat)
|
Zidovudine results in decreased expression of ABCG2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Rattus norvegicus (Norway rat)
|
Zidovudine results in increased expression of ABCG2 protein
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Homo sapiens (human)
|
[[chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with glyphosate] results in decreased susceptibility to cisplatin] which results in increased expression of ABCG2 mrna|[[chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with glyphosate] results in decreased susceptibility to fluorouracil] which results in increased expression of ABCG2 protein|[[chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with glyphosate] results in decreased susceptibility to fluorouracil] which results in increased expression of ABCG2 mrna|[[chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with glyphosate] results in decreased susceptibility to cisplatin] which results in increased expression of ABCG2 protein|[[chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with glyphosate] results in decreased susceptibility to temozolomide] which results in increased expression of ABCG2 protein|[[chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with glyphosate] results in decreased susceptibility to temozolomide] which results in increased expression of ABCG2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Homo sapiens (human)
|
|
https://www.dgidb.org/genes/hgnc:74
|
||
|
ABCG2
|
Homo sapiens (human)
|
ABCG2 mutant form inhibits the reaction [ERBB2 results in decreased susceptibility to doxorubicin]|[erbb2 results in increased expression of ABCG2] which results in decreased susceptibility to doxorubicin
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Homo sapiens (human)
|
ABCG2 protein affects the susceptibility to doxorubicin|doxorubicin results in increased expression of ABCG2 protein
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Homo sapiens (human)
|
ABCG2 protein affects the transport of doxorubicin
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Homo sapiens (human)
|
Gefitinib inhibits the reaction [ABCG2 protein results in decreased susceptibility to doxorubicin]|abcg2 protein results in decreased susceptibility to doxorubicin|[[gefitinib results in decreased activity of EGFR protein] which affects the localization of ABCG2 protein] which results in decreased export of doxorubicin
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Homo sapiens (human)
|
Abemaciclib inhibits the reaction [ABCG2 protein results in increased export of doxorubicin]|abcg2 protein results in increased export of doxorubicin
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Homo sapiens (human)
|
ABCG2 results in decreased abundance of and results in decreased susceptibility to doxorubicin|sunitinib inhibits the reaction [ABCG2 results in decreased abundance of and results in decreased susceptibility to doxorubicin]
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Homo sapiens (human)
|
Doxorubicin results in increased expression of ABCG2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Homo sapiens (human)
|
[paclitaxel results in decreased expression of ABCG2] which results in decreased susceptibility to doxorubicin
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Homo sapiens (human)
|
ABCG2 results in decreased susceptibility to doxorubicin
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Homo sapiens (human)
|
Dactinomycin inhibits the reaction [doxorubicin results in increased expression of ABCG2 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Homo sapiens (human)
|
[NOG protein co-treated with valproic acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ABCG2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Homo sapiens (human)
|
Valproic acid affects the expression of ABCG2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Homo sapiens (human)
|
Valproic acid results in increased expression of ABCG2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Mus musculus (house mouse)
|
Valproic acid results in increased expression of ABCG2 protein
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Rattus norvegicus (Norway rat)
|
Valproic acid results in increased expression of ABCG2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Homo sapiens (human)
|
|
https://www.dgidb.org/genes/hgnc:74
|
||
|
ABCG2
|
Rattus norvegicus (Norway rat)
|
Diethylstilbestrol results in increased expression of ABCG2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
||
|
ABCG2
|
Homo sapiens (human)
|
Oleic acid results in increased expression of ABCG2 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=9429
|
No matching records found on this page.