Molecular Targets : Dataset Browser

BIMP_ID	Target Name	Gene	Organism	Action	Source URL
BIMP068482	ABCG2	ABCG2	Homo sapiens (human)	6,2',4'-trimethoxyflavone inhibits the reaction [benzo(a)pyrene results in increased expression of ABCG2 protein]\|n-(2-(3H-indol-3-yl)ethyl)-9-isopropyl-2-(5-methyl-3-pyridyl)purin-6-amine inhibits the reaction [benzo(a)pyrene results in increased expression of ABCG2 protein]	https://ctdbase.org/detail.go?type=gene&acc=9429
BIMP068482	ABCG2	ABCG2	Homo sapiens (human)	Benzo(a)pyrene results in decreased methylation of ABCG2 5' utr\|benzo(a)pyrene results in increased methylation of ABCG2 intron	https://ctdbase.org/detail.go?type=gene&acc=9429
BIMP068482	ABCG2	ABCG2	Homo sapiens (human)	Benzo(a)pyrene results in increased activity of ABCG2 protein	https://ctdbase.org/detail.go?type=gene&acc=9429
BIMP068482	ABCG2	ABCG2	Homo sapiens (human)	Benzo(a)pyrene results in increased expression of ABCG2 mRNA	https://ctdbase.org/detail.go?type=gene&acc=9429
BIMP068482	ABCG2	ABCG2	Homo sapiens (human)	Benzo(a)pyrene results in increased expression of ABCG2 protein	https://ctdbase.org/detail.go?type=gene&acc=9429
BIMP068482	ABCG2	ABCG2	Mus musculus (house mouse)	ABCG2 protein results in increased transport of benzo(a)pyrene metabolite\|abcg2 protein results in increased transport of benzo(a)pyrene	https://ctdbase.org/detail.go?type=gene&acc=9429
BIMP068482	ABCG2	ABCG2	Mytilus galloprovincialis (Mediterranean mussel)	Benzo(a)pyrene results in decreased expression of ABCG2 mRNA	https://ctdbase.org/detail.go?type=gene&acc=9429
BIMP068482	ABCG2	ABCG2	Oreochromis niloticus (Nile tilapia)	Benzo(a)pyrene results in increased expression of ABCG2 mRNA	https://ctdbase.org/detail.go?type=gene&acc=9429
BIMP070805	ABCG2	ABCG2	Homo sapiens (human)	ABCG2 protein affects the reaction [3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester results in decreased transport of pheophorbide a]\|abcg2 protein affects the reaction [mifepristone results in decreased transport of pheophorbide a]	https://ctdbase.org/detail.go?type=gene&acc=9429
BIMP070805	ABCG2	ABCG2	Homo sapiens (human)	ABCG2 protein results in increased export of pheophorbide a analog	https://ctdbase.org/detail.go?type=gene&acc=9429
BIMP070821	ABCG2	ABCG2	Oryctolagus cuniculus (rabbit)	Carbendazim inhibits the reaction [ABCG2 protein results in increased secretion of bisbenzimide ethoxide trihydrochloride]	https://ctdbase.org/detail.go?type=gene&acc=9429
BIMP070935	ABCG2	ABCG2	Mus musculus (house mouse)	Lupeol results in decreased expression of ABCG2 protein	https://ctdbase.org/detail.go?type=gene&acc=9429
BIMP068581	ABCG2	ABCG2	Rattus norvegicus (Norway rat)	[diethyl phthalate co-treated with diethylhexyl phthalate co-treated with dibutyl phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of ABCG2 mRNA	https://ctdbase.org/detail.go?type=gene&acc=9429
BIMP068606	ABCG2	ABCG2	Homo sapiens (human)	Novobiocin inhibits the reaction [[5-methoxypsoralen results in decreased activity of ABCG2 protein] which results in decreased export of and results in increased abundance of mitoxantrone]\|5-methoxypsoralen results in decreased activity of ABCG2 protein\|novobiocin inhibits the reaction [5-methoxypsoralen results in decreased activity of ABCG2 protein]\|5-methoxypsoralen results in increased expression of ABCG2 mrna\|[5-methoxypsoralen results in decreased activity of ABCG2 protein] which results in decreased export of and results in increased abundance of mitoxantrone	https://ctdbase.org/detail.go?type=gene&acc=9429
BIMP071142	ABCG2	ABCG2	Homo sapiens (human)	Chloroquine results in decreased expression of ABCG2 protein\|chloroquine results in decreased expression of ABCG2 mRNA	https://ctdbase.org/detail.go?type=gene&acc=9429
BIMP071048	ABCG2	ABCG2	Homo sapiens (human)	Butyric acid results in increased expression of ABCG2 mRNA	https://ctdbase.org/detail.go?type=gene&acc=9429
BIMP073146	ABCG2	ABCG2	Homo sapiens (human)	Indole-3-carbinol results in increased expression of ABCG2 mRNA	https://ctdbase.org/detail.go?type=gene&acc=9429
BIMP073059	ABCG2	ABCG2	Homo sapiens (human)	ABCG2 mutant form inhibits the reaction [ERBB2 results in decreased susceptibility to etoposide]\|[erbb2 results in increased expression of ABCG2] which results in decreased susceptibility to etoposide	https://ctdbase.org/detail.go?type=gene&acc=9429
BIMP072777	ABCG2	ABCG2	Rattus norvegicus (Norway rat)	Gentamicins affects the expression of ABCG2 mRNA	https://ctdbase.org/detail.go?type=gene&acc=9429
BIMP072777	ABCG2	ABCG2	Rattus norvegicus (Norway rat)	Gentamicins results in increased expression of ABCG2 protein	https://ctdbase.org/detail.go?type=gene&acc=9429
BIMP072829	ABCG2	ABCG2	Homo sapiens (human)	3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein results in increased export of glyburide]\|abcg2 protein polymorphism results in decreased export of glyburide\|abcg2 protein results in increased export of glyburide\|3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester promotes the reaction [ABCG2 protein polymorphism results in decreased export of glyburide]\|genistein promotes the reaction [ABCG2 protein polymorphism results in decreased export of glyburide]\|genistein inhibits the reaction [ABCG2 protein results in increased export of glyburide]	https://ctdbase.org/detail.go?type=gene&acc=9429
BIMP072653	ABCG2	ABCG2	Homo sapiens (human)	ABCG2 mutant form inhibits the reaction [ERBB2 results in decreased susceptibility to fluorouracil]\|[erbb2 results in increased expression of ABCG2] which results in decreased susceptibility to fluorouracil	https://ctdbase.org/detail.go?type=gene&acc=9429
BIMP072653	ABCG2	ABCG2	Homo sapiens (human)	ABCG2 protein affects the susceptibility to [fluorouracil co-treated with epirubicin co-treated with cyclophosphamide]	https://ctdbase.org/detail.go?type=gene&acc=9429
BIMP072653	ABCG2	ABCG2	Homo sapiens (human)	[[chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with glyphosate] results in decreased susceptibility to fluorouracil] which results in increased expression of ABCG2 protein\|[[chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with glyphosate] results in decreased susceptibility to fluorouracil] which results in increased expression of ABCG2 mRNA	https://ctdbase.org/detail.go?type=gene&acc=9429
BIMP072653	ABCG2	ABCG2	Homo sapiens (human)	[paclitaxel results in decreased expression of ABCG2] which results in decreased susceptibility to fluorouracil	https://ctdbase.org/detail.go?type=gene&acc=9429

BIMP068482

ABCG2

Homo sapiens (human)

6,2',4'-trimethoxyflavone inhibits the reaction [benzo(a)pyrene results in increased expression of ABCG2 protein]|n-(2-(3H-indol-3-yl)ethyl)-9-isopropyl-2-(5-methyl-3-pyridyl)purin-6-amine inhibits the reaction [benzo(a)pyrene results in increased expression of ABCG2 protein]