SCFBio, IIT Delhi
Hauz Khas, New Delhi
BIMP
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SCFBio, IIT Delhi
Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
HTR2A
|
Homo sapiens (human)
|
LSH acts as an agonist at 5-HT2 receptors, causing direct stimulation of the uterine smooth musculature, resulting in increased muscular tone and an enhancement of the rate and force of rhythmical contractions. (A2919)
|
http://www.t3db.ca/biodb/bio_entities/BE0000451
|
||
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HTR2A
|
Homo sapiens (human)
|
Ergovalie acts as an agonist at vascular 5-HT2A receptors, causing the constriction of blood vessels. (A2924)
|
http://www.t3db.ca/biodb/bio_entities/BE0000451
|
||
|
HTR2A
|
Homo sapiens (human)
|
Bufotenin is a neurotoxin similar to the mushroom toxin psilocin. thus it likely acts as a partial agonist at the 5-HT2A serotonin receptor in the brain where it mimics the effects of serotonin (5-HT). it is likely also a 5-HT1A and 5-HT2A/2C agonist. (L1081, L1673)
|
http://www.t3db.ca/biodb/bio_entities/BE0000451
|
||
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HTR2A
|
Homo sapiens (human)
|
Psilocybin is rapidly dephosphorylated in the body to psilocin which then acts as a partial agonist at the 5-HT2A serotonin receptor in the brain where it mimics the effects of serotonin (5-HT). psilocin is an 5-HT1A and 5-HT2A/2C agonist. (L1143)
|
http://www.t3db.ca/biodb/bio_entities/BE0000451
|
||
|
HTR2A
|
Homo sapiens (human)
|
Agonist
|
https://www.drugbank.ca/bio_entities/BE0000451
|
||
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HTR2A
|
Homo sapiens (human)
|
Antagonist
|
https://www.drugbank.ca/bio_entities/BE0000451
|
||
|
HTR2A
|
Homo sapiens (human)
|
Aripiprazole exhibits high affinity for dopamine D2 and D3, serotonin 5-HT1A and 5- HT2A receptors, moderate affinity for dopamine D4, serotonin 5-HT2C and 5-HT7, alpha1-adrenergic and histamine H1 receptors and moderate affinity for the serotonin reuptake pump. aripiprazole has no appreciable affinity for cholinergic muscarinic receptors. aripiprazole functions as a partial agonist at the dopamine D2 and the serotonin 5-HT1A receptors, and as an antagonist at serotonin 5-HT2A receptor.
|
http://www.t3db.ca/biodb/bio_entities/BE0000451
|
||
|
HTR2A
|
Homo sapiens (human)
|
|
https://www.drugbank.ca/bio_entities/BE0000451
|
||
|
HTR2A
|
Homo sapiens (human)
|
|
https://www.drugbank.ca/bio_entities/BE0000451
|
||
|
HTR2A
|
Homo sapiens (human)
|
|
http://www.t3db.ca/biodb/bio_entities/BE0000451
|
||
|
HTR2A
|
Homo sapiens (human)
|
|
http://www.t3db.ca/biodb/bio_entities/BE0000451
|
||
|
HTR2A
|
Homo sapiens (human)
|
Antagonist
|
https://www.drugbank.ca/bio_entities/BE0000451
|
||
|
HTR2A
|
Homo sapiens (human)
|
Ergometrine acts as an agonist at 5-HT2 receptors, causing direct stimulation of the uterine smooth musculature, resulting in increased muscular tone and an enhancement of the rate and force of rhythmical contractions. (A2915)
|
http://www.t3db.ca/biodb/bio_entities/BE0000451
|
||
|
HTR2B
|
Homo sapiens (human)
|
Ergometrine acts as an agonist at 5-HT2 receptors, causing direct stimulation of the uterine smooth musculature, resulting in increased muscular tone and an enhancement of the rate and force of rhythmical contractions. (A2915)
|
http://www.t3db.ca/biodb/bio_entities/BE0000393
|
||
|
HTR2B
|
Homo sapiens (human)
|
|
http://www.t3db.ca/biodb/bio_entities/BE0000393
|
||
|
HTR2B
|
Homo sapiens (human)
|
|
http://www.t3db.ca/biodb/bio_entities/BE0000393
|
||
|
HTR2B
|
Homo sapiens (human)
|
LSH acts as an agonist at 5-HT2 receptors, causing direct stimulation of the uterine smooth musculature, resulting in increased muscular tone and an enhancement of the rate and force of rhythmical contractions. (A2919)
|
http://www.t3db.ca/biodb/bio_entities/BE0000393
|
||
|
HTR2B
|
Homo sapiens (human)
|
|
http://www.t3db.ca/biodb/bio_entities/BE0000393
|
||
|
HTR2B
|
Homo sapiens (human)
|
|
https://www.drugbank.ca/bio_entities/BE0000393
|
||
|
HTR2B
|
Homo sapiens (human)
|
Ergotamine acts as an agonist at 5-HT2 receptors, causing vasoconstriction. (A1505, A1506, A365)
|
http://www.t3db.ca/biodb/bio_entities/BE0000393
|
||
|
HTR2B
|
Homo sapiens (human)
|
Inverse agonist
|
https://www.drugbank.ca/bio_entities/BE0000393
|
||
|
HTR2B
|
Homo sapiens (human)
|
|
http://www.t3db.ca/biodb/bio_entities/BE0000393
|
||
|
HTR2C
|
Homo sapiens (human)
|
Antagonist|Partial agonist
|
https://www.drugbank.ca/bio_entities/BE0000533
|
||
|
HTR2C
|
Homo sapiens (human)
|
|
http://www.t3db.ca/biodb/bio_entities/BE0000533
|
||
|
HTR2C
|
Homo sapiens (human)
|
|
http://www.t3db.ca/biodb/bio_entities/BE0000533
|
No matching records found on this page.