BIMP Logo
SCFBio, IIT Delhi Hauz Khas, New Delhi
MOLECULAR TARGET

5-hydroxytryptamine receptor 2A

View External Source

23

Interactions

Homo sapiens (human)

Organism

HTR2A

Gene Name

Compound Associations

S.No BIMP ID Organism Action References
1 BIMP101253 Homo sapiens (human) Agonist
2 BIMP101253 Homo sapiens (human) Ergotamine acts as an agonist at 5-HT2 receptors, causing vasoconstriction. (A1505, A1506, A365)
3 BIMP105331 Homo sapiens (human) -
4 BIMP102821 Homo sapiens (human) -
5 BIMP091293 Homo sapiens (human) Antagonist
6 BIMP091293 Homo sapiens (human) Aripiprazole exhibits high affinity for dopamine D2 and D3, serotonin 5-HT1A and 5- HT2A receptors, moderate affinity for dopamine D4, serotonin 5-HT2C and 5-HT7, alpha1-adrenergic and histamine H1 receptors and moderate affinity for the serotonin reuptake pump. aripiprazole has no appreciable affinity for cholinergic muscarinic receptors. aripiprazole functions as a partial agonist at the dopamine D2 and the serotonin 5-HT1A receptors, and as an antagonist at serotonin 5-HT2A receptor.
7 BIMP091309 Homo sapiens (human) -
8 BIMP093437 Homo sapiens (human) Agonist
9 BIMP098141 Homo sapiens (human) -
10 BIMP098119 Homo sapiens (human) Agroclavin moderates the activity of the serotonin and noradrenergic systems of the brain by acting as an antagonist and partial agonist of 5-HT2A receptors. (A2925)
11 BIMP081628 Homo sapiens (human) -
12 BIMP079116 Homo sapiens (human) -
13 BIMP079116 Homo sapiens (human) Antagonist
14 BIMP076702 Homo sapiens (human) Ergometrine acts as an agonist at 5-HT2 receptors, causing direct stimulation of the uterine smooth musculature, resulting in increased muscular tone and an enhancement of the rate and force of rhythmical contractions. (A2915)
15 BIMP072654 Homo sapiens (human) -
16 BIMP032544 Homo sapiens (human) Lysergol moderates the activity of the serotonin and noradrenergic systems of the brain by acting as an antagonist and partial agonist of 5-HT receptors. this also causes vasoconstriction. (A2925, A2931)
17 BIMP066605 Homo sapiens (human) -
18 BIMP026163 Homo sapiens (human) LSH acts as an agonist at 5-HT2 receptors, causing direct stimulation of the uterine smooth musculature, resulting in increased muscular tone and an enhancement of the rate and force of rhythmical contractions. (A2919)
19 BIMP011339 Homo sapiens (human) Ergovalie acts as an agonist at vascular 5-HT2A receptors, causing the constriction of blood vessels. (A2924)
20 BIMP009815 Homo sapiens (human) Bufotenin is a neurotoxin similar to the mushroom toxin psilocin. thus it likely acts as a partial agonist at the 5-HT2A serotonin receptor in the brain where it mimics the effects of serotonin (5-HT). it is likely also a 5-HT1A and 5-HT2A/2C agonist. (L1081, L1673)
21 BIMP012019 Homo sapiens (human) Psilocybin is rapidly dephosphorylated in the body to psilocin which then acts as a partial agonist at the 5-HT2A serotonin receptor in the brain where it mimics the effects of serotonin (5-HT). psilocin is an 5-HT1A and 5-HT2A/2C agonist. (L1143)
No ref
22 BIMP064165 Homo sapiens (human) Agonist
23 BIMP037066 Homo sapiens (human) Costaclavine moderates the activity of the serotonin and noradrenergic systems of the brain by acting as an antagonist and partial agonist of 5-HT2A receptors. (A2925)