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SCFBio, IIT Delhi Hauz Khas, New Delhi

Molecular Targets

Interactions between compounds and specific gene/protein targets.

Total Rows 750,454
Pages 30,019
BIMP_ID Target Name Gene Organism Action Source URL
HTR1B
Homo sapiens (human)
Ergotamine acts as an agonist at 5-HT1B receptors located on intracranial blood vessels, including those on arterio-venous anastomoses, leading to vasoconstriction. it also activates 5-HT1B receptors on sensory nerve endings of the trigeminal system, resulting in the inhibition of pro-inflammatory neuropeptide release. (A1503, A948, A1462, A1504)
http://www.t3db.ca/biodb/bio_entities/BE0000797
HTR1B
Homo sapiens (human)
Lysergol moderates the activity of the serotonin and noradrenergic systems of the brain by acting as an antagonist and partial agonist of 5-HT receptors. this also causes vasoconstriction. (A2925, A2931)
http://www.t3db.ca/biodb/bio_entities/BE0000797
HTR1B
Homo sapiens (human)
Ergovalie acts as an agonist at vascular 5-HT1B receptors, causing the constriction of blood vessels. (A2924)
http://www.t3db.ca/biodb/bio_entities/BE0000797
HTR1D
Homo sapiens (human)
Ergovalie acts as an agonist at vascular 5-HT1D receptors, causing the constriction of blood vessels. (A2924)
http://www.t3db.ca/biodb/bio_entities/BE0000659
HTR1D
Homo sapiens (human)
http://www.t3db.ca/biodb/bio_entities/BE0000659
HTR1D
Homo sapiens (human)
Agonist
https://www.drugbank.ca/bio_entities/BE0000659
HTR1D
Homo sapiens (human)
Ergotamine acts as an agonist at 5-HT1D receptors located on intracranial blood vessels, including those on arterio-venous anastomoses, leading to vasoconstriction. it also activates 5-HT1D receptors on sensory nerve endings of the trigeminal system, resulting in the inhibition of pro-inflammatory neuropeptide release. (A946, A1500, A947, A1501, A1502)
http://www.t3db.ca/biodb/bio_entities/BE0000659
HTR1D
Homo sapiens (human)
Antagonist|Ligand
https://www.drugbank.ca/bio_entities/BE0000659
HTR1D
Homo sapiens (human)
http://www.t3db.ca/biodb/bio_entities/BE0000659
HTR1E
Homo sapiens (human)
Antagonist|Ligand
https://www.drugbank.ca/bio_entities/BE0000476
HTR1E
Homo sapiens (human)
http://www.t3db.ca/biodb/bio_entities/BE0000476
HTR1E
Homo sapiens (human)
http://www.t3db.ca/biodb/bio_entities/BE0000476
HTR1F
Homo sapiens (human)
Agonist
https://www.drugbank.ca/bio_entities/BE0000460
HTR1F
Homo sapiens (human)
http://www.t3db.ca/biodb/bio_entities/BE0000460
HTR1F
Homo sapiens (human)
http://www.t3db.ca/biodb/bio_entities/BE0000460
HTR2A
Homo sapiens (human)
Agonist
https://www.drugbank.ca/bio_entities/BE0000451
HTR2A
Homo sapiens (human)
Ergotamine acts as an agonist at 5-HT2 receptors, causing vasoconstriction. (A1505, A1506, A365)
http://www.t3db.ca/biodb/bio_entities/BE0000451
HTR2A
Homo sapiens (human)
https://www.drugbank.ca/bio_entities/BE0000451
HTR2A
Homo sapiens (human)
http://www.t3db.ca/biodb/bio_entities/BE0000451
HTR2A
Homo sapiens (human)
Agonist
https://www.drugbank.ca/bio_entities/BE0000451
HTR2A
Homo sapiens (human)
Agroclavin moderates the activity of the serotonin and noradrenergic systems of the brain by acting as an antagonist and partial agonist of 5-HT2A receptors. (A2925)
http://www.t3db.ca/biodb/bio_entities/BE0000451
HTR2A
Homo sapiens (human)
https://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?tag=pol&polymerid=687
HTR2A
Homo sapiens (human)
Lysergol moderates the activity of the serotonin and noradrenergic systems of the brain by acting as an antagonist and partial agonist of 5-HT receptors. this also causes vasoconstriction. (A2925, A2931)
http://www.t3db.ca/biodb/bio_entities/BE0000451
HTR2A
Homo sapiens (human)
Costaclavine moderates the activity of the serotonin and noradrenergic systems of the brain by acting as an antagonist and partial agonist of 5-HT2A receptors. (A2925)
http://www.t3db.ca/biodb/bio_entities/BE0000451
HTR2A
Homo sapiens (human)
http://www.t3db.ca/biodb/bio_entities/BE0000451
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