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Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
HTR1B
|
Homo sapiens (human)
|
Ergotamine acts as an agonist at 5-HT1B receptors located on intracranial blood vessels, including those on arterio-venous anastomoses, leading to vasoconstriction. it also activates 5-HT1B receptors on sensory nerve endings of the trigeminal system, resulting in the inhibition of pro-inflammatory neuropeptide release. (A1503, A948, A1462, A1504)
|
http://www.t3db.ca/biodb/bio_entities/BE0000797
|
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HTR1B
|
Homo sapiens (human)
|
Lysergol moderates the activity of the serotonin and noradrenergic systems of the brain by acting as an antagonist and partial agonist of 5-HT receptors. this also causes vasoconstriction. (A2925, A2931)
|
http://www.t3db.ca/biodb/bio_entities/BE0000797
|
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HTR1B
|
Homo sapiens (human)
|
Ergovalie acts as an agonist at vascular 5-HT1B receptors, causing the constriction of blood vessels. (A2924)
|
http://www.t3db.ca/biodb/bio_entities/BE0000797
|
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HTR1D
|
Homo sapiens (human)
|
Ergovalie acts as an agonist at vascular 5-HT1D receptors, causing the constriction of blood vessels. (A2924)
|
http://www.t3db.ca/biodb/bio_entities/BE0000659
|
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HTR1D
|
Homo sapiens (human)
|
|
http://www.t3db.ca/biodb/bio_entities/BE0000659
|
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HTR1D
|
Homo sapiens (human)
|
Agonist
|
https://www.drugbank.ca/bio_entities/BE0000659
|
||
|
HTR1D
|
Homo sapiens (human)
|
Ergotamine acts as an agonist at 5-HT1D receptors located on intracranial blood vessels, including those on arterio-venous anastomoses, leading to vasoconstriction. it also activates 5-HT1D receptors on sensory nerve endings of the trigeminal system, resulting in the inhibition of pro-inflammatory neuropeptide release. (A946, A1500, A947, A1501, A1502)
|
http://www.t3db.ca/biodb/bio_entities/BE0000659
|
||
|
HTR1D
|
Homo sapiens (human)
|
Antagonist|Ligand
|
https://www.drugbank.ca/bio_entities/BE0000659
|
||
|
HTR1D
|
Homo sapiens (human)
|
|
http://www.t3db.ca/biodb/bio_entities/BE0000659
|
||
|
HTR1E
|
Homo sapiens (human)
|
Antagonist|Ligand
|
https://www.drugbank.ca/bio_entities/BE0000476
|
||
|
HTR1E
|
Homo sapiens (human)
|
|
http://www.t3db.ca/biodb/bio_entities/BE0000476
|
||
|
HTR1E
|
Homo sapiens (human)
|
|
http://www.t3db.ca/biodb/bio_entities/BE0000476
|
||
|
HTR1F
|
Homo sapiens (human)
|
Agonist
|
https://www.drugbank.ca/bio_entities/BE0000460
|
||
|
HTR1F
|
Homo sapiens (human)
|
|
http://www.t3db.ca/biodb/bio_entities/BE0000460
|
||
|
HTR1F
|
Homo sapiens (human)
|
|
http://www.t3db.ca/biodb/bio_entities/BE0000460
|
||
|
HTR2A
|
Homo sapiens (human)
|
Agonist
|
https://www.drugbank.ca/bio_entities/BE0000451
|
||
|
HTR2A
|
Homo sapiens (human)
|
Ergotamine acts as an agonist at 5-HT2 receptors, causing vasoconstriction. (A1505, A1506, A365)
|
http://www.t3db.ca/biodb/bio_entities/BE0000451
|
||
|
HTR2A
|
Homo sapiens (human)
|
|
https://www.drugbank.ca/bio_entities/BE0000451
|
||
|
HTR2A
|
Homo sapiens (human)
|
|
http://www.t3db.ca/biodb/bio_entities/BE0000451
|
||
|
HTR2A
|
Homo sapiens (human)
|
Agonist
|
https://www.drugbank.ca/bio_entities/BE0000451
|
||
|
HTR2A
|
Homo sapiens (human)
|
Agroclavin moderates the activity of the serotonin and noradrenergic systems of the brain by acting as an antagonist and partial agonist of 5-HT2A receptors. (A2925)
|
http://www.t3db.ca/biodb/bio_entities/BE0000451
|
||
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HTR2A
|
Homo sapiens (human)
|
|
https://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?tag=pol&polymerid=687
|
||
|
HTR2A
|
Homo sapiens (human)
|
Lysergol moderates the activity of the serotonin and noradrenergic systems of the brain by acting as an antagonist and partial agonist of 5-HT receptors. this also causes vasoconstriction. (A2925, A2931)
|
http://www.t3db.ca/biodb/bio_entities/BE0000451
|
||
|
HTR2A
|
Homo sapiens (human)
|
Costaclavine moderates the activity of the serotonin and noradrenergic systems of the brain by acting as an antagonist and partial agonist of 5-HT2A receptors. (A2925)
|
http://www.t3db.ca/biodb/bio_entities/BE0000451
|
||
|
HTR2A
|
Homo sapiens (human)
|
|
http://www.t3db.ca/biodb/bio_entities/BE0000451
|
No matching records found on this page.