Molecular Targets : Dataset Browser

BIMP_ID	Target Name	Gene	Organism	Action	Source URL
BIMP101295	ABCC8	ABCC8	Homo sapiens (human)	Diethylhexyl phthalate results in decreased expression of ABCC8 mRNA	https://ctdbase.org/detail.go?type=gene&acc=6833
BIMP101295	ABCC8	ABCC8	Mus musculus (house mouse)	Diethylhexyl phthalate results in increased expression of ABCC8 mRNA	https://ctdbase.org/detail.go?type=gene&acc=6833
BIMP101342	ABCC8	ABCC8	Homo sapiens (human)	Ethyl-p-hydroxybenzoate results in decreased expression of ABCC8 mRNA	https://ctdbase.org/detail.go?type=gene&acc=6833
BIMP103258	ABCC8	ABCC8	Homo sapiens (human)	Benzo(e)pyrene results in increased methylation of ABCC8 intron	https://ctdbase.org/detail.go?type=gene&acc=6833
BIMP064420	ABCC8	ABCC8	Homo sapiens (human)	Aflatoxin B1 results in increased methylation of ABCC8 exon	https://ctdbase.org/detail.go?type=gene&acc=6833
BIMP064424	ABCC8	ABCC8	Rattus norvegicus (Norway rat)	ABCC8 protein inhibits the reaction [acetylcholine promotes the reaction [KCNJ8 protein results in increased transport of potassium]]	https://ctdbase.org/detail.go?type=gene&acc=6833
BIMP068094	ABCC8	ABCC8	Homo sapiens (human)	Atrazine results in decreased expression of ABCC8 mRNA	https://ctdbase.org/detail.go?type=gene&acc=6833
BIMP068094	ABCC8	ABCC8	Rattus norvegicus (Norway rat)	Atrazine affects the methylation of ABCC8 gene	https://ctdbase.org/detail.go?type=gene&acc=6833
BIMP036503	ABCC8	ABCC8	Rattus norvegicus (Norway rat)	Schizandrin B inhibits the reaction [carbon tetrachloride results in decreased expression of ABCC8 mrna]	https://ctdbase.org/detail.go?type=gene&acc=6833
BIMP026434	ABCC8	ABCC8	Mus musculus (house mouse)	[1,2-dimethylhydrazine co-treated with folic acid] results in increased expression of ABCC8 mRNA	https://ctdbase.org/detail.go?type=gene&acc=6833
BIMP037097	ABCC8	ABCC8	Homo sapiens (human)	Abrine results in decreased expression of ABCC8 mRNA	https://ctdbase.org/detail.go?type=gene&acc=6833
BIMP089333	ABCC8	ABCC8	Homo sapiens (human)	Mifepristone results in decreased expression of ABCC8 mRNA	https://ctdbase.org/detail.go?type=gene&acc=6833
BIMP090535	ABCC8	ABCC8	Mus musculus (house mouse)	ABCC8 protein promotes the reaction [estradiol results in increased activity of CASP9 protein]\|estradiol inhibits the reaction [glyburide binds to ABCC8 protein mutant form]\|abcc8 protein promotes the reaction [estradiol results in increased activity of CASP8 protein]\|abcc8 protein promotes the reaction [estradiol results in increased activity of CASP3 protein]\|abcc8 protein results in increased susceptibility to estradiol\|abcc8 protein mutant form results in increased susceptibility to estradiol\|estradiol inhibits the reaction [glyburide binds to ABCC8 protein]\|abcc8 protein mutant form results in decreased susceptibility to estradiol\|adenosine triphosphate deficiency inhibits the reaction [estradiol inhibits the reaction [glyburide binds to ABCC8 protein]]\|abcc8 protein affects the susceptibility to estradiol\|estradiol binds to and affects the activity of ABCC8 protein\|estradiol binds to ABCC8 protein mutant form	https://ctdbase.org/detail.go?type=gene&acc=6833
BIMP090535	ABCC8	ABCC8	Rattus norvegicus (Norway rat)	[estradiol 3-benzoate co-treated with [testosterone co-treated with estradiol]] results in increased expression of ABCC8 mRNA	https://ctdbase.org/detail.go?type=gene&acc=6833
BIMP090429	ABCC8	ABCC8	Danio rerio (zebrafish)	Dexamethasone inhibits the reaction [RX3 gene mutant form affects the expression of ABCC8 mrna]	https://ctdbase.org/detail.go?type=gene&acc=6833
BIMP091430	ABCC8	ABCC8	Rattus norvegicus (Norway rat)	Dimethylnitrosamine results in decreased expression of ABCC8 mRNA	https://ctdbase.org/detail.go?type=gene&acc=6833
BIMP091110	ABCC8	ABCC8	Rattus norvegicus (Norway rat)	[estradiol 3-benzoate co-treated with [testosterone co-treated with estradiol]] results in increased expression of ABCC8 mRNA	https://ctdbase.org/detail.go?type=gene&acc=6833
BIMP082212	ABCC8	ABCC8	Rattus norvegicus (Norway rat)	Flavonoids results in increased expression of ABCC8 mRNA	https://ctdbase.org/detail.go?type=gene&acc=6833
BIMP085926	ABCC8	ABCC8	Rattus norvegicus (Norway rat)	Sulfadimethoxine results in decreased expression of ABCC8 mRNA	https://ctdbase.org/detail.go?type=gene&acc=6833
BIMP090994	ABCC8	ABCC8	Rattus norvegicus (Norway rat)	Adenosine triphosphate deficiency inhibits the reaction [estradiol inhibits the reaction [glyburide binds to ABCC8 protein]]	https://ctdbase.org/detail.go?type=gene&acc=6833
BIMP090784	ABCC8	ABCC8	Rattus norvegicus (Norway rat)	ABCC8 protein results in increased susceptibility to estrone	https://ctdbase.org/detail.go?type=gene&acc=6833
BIMP082231	ABCC8	ABCC8	Mus musculus (house mouse)	Genistein results in increased expression of ABCC8 mRNA	https://ctdbase.org/detail.go?type=gene&acc=6833
BIMP082231	ABCC9	ABCC9	Mus musculus (house mouse)	Genistein results in increased expression of ABCC9 mRNA	https://ctdbase.org/detail.go?type=gene&acc=10060
BIMP082231	ABCC9	ABCC9	Rattus norvegicus (Norway rat)	Genistein results in increased expression of ABCC9 mRNA	https://ctdbase.org/detail.go?type=gene&acc=10060
BIMP082446	ABCC9	ABCC9	Sus scrofa (pig)	Zearalenone results in decreased expression of ABCC9 mRNA	https://ctdbase.org/detail.go?type=gene&acc=10060

BIMP101295

ABCC8

Homo sapiens (human)

Diethylhexyl phthalate results in decreased expression of ABCC8 mRNA