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SCFBio, IIT Delhi Hauz Khas, New Delhi
MOLECULAR TARGET

ABCC8

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50

Interactions

Rattus norvegicus (Norway rat)

Organism

ABCC8

Gene Name

Compound Associations

S.No BIMP ID Organism Action References
1 BIMP068482 Rattus norvegicus (Norway rat) Benzo(a)pyrene affects the methylation of ABCC8 intron
2 BIMP068482 Rattus norvegicus (Norway rat) Benzo(a)pyrene results in increased methylation of ABCC8 5' utr|benzo(a)pyrene results in increased methylation of ABCC8 intron|benzo(a)pyrene affects the methylation of ABCC8 promoter|benzo(a)pyrene results in increased methylation of ABCC8 exon
3 BIMP068482 Rattus norvegicus (Norway rat) Benzo(a)pyrene promotes the reaction [AHR protein binds to ABCC8 promoter]
4 BIMP072249 Rattus norvegicus (Norway rat) Picrotoxin results in increased expression of ABCC8 mrna|picrotoxin results in decreased expression of ABCC8 mrna|picrotoxin results in increased expression of ABCC8 protein
5 BIMP077135 Rattus norvegicus (Norway rat) [plant extracts co-treated with resveratrol] results in decreased expression of ABCC8 mRNA
6 BIMP077135 Rattus norvegicus (Norway rat) Resveratrol affects the activity of ABCC8 protein|abcc8 protein results in increased susceptibility to resveratrol
7 BIMP077135 Rattus norvegicus (Norway rat) Resveratrol inhibits the reaction [glyburide binds to ABCC8 protein]|resveratrol binds to ABCC8 protein
8 BIMP072777 Rattus norvegicus (Norway rat) Gentamicins results in increased expression of ABCC8 mRNA
9 BIMP072829 Rattus norvegicus (Norway rat) Inhibitor
10 BIMP072829 Rattus norvegicus (Norway rat) Estradiol inhibits the reaction [glyburide binds to ABCC8 protein mutant form]|abcc8 protein results in increased susceptibility to glyburide|glyburide binds to ABCC8 protein|glyburide binds to ABCC8 protein mutant form|estradiol inhibits the reaction [glyburide binds to ABCC8 protein]|adenosine triphosphate deficiency inhibits the reaction [estradiol inhibits the reaction [glyburide binds to ABCC8 protein]]
11 BIMP072829 Rattus norvegicus (Norway rat) Resveratrol inhibits the reaction [glyburide binds to ABCC8 protein]
12 BIMP072829 Rattus norvegicus (Norway rat) Glyburide binds to and results in decreased activity of ABCC8 protein
13 BIMP072829 Rattus norvegicus (Norway rat) -
No ref
14 BIMP072829 Rattus norvegicus (Norway rat) Blocker
No ref
15 BIMP072798 Rattus norvegicus (Norway rat) Blocker
No ref
16 BIMP072798 Rattus norvegicus (Norway rat) -
No ref
17 BIMP072798 Rattus norvegicus (Norway rat) [KCNJ11 mutant form co-treated with ABCC8 mutant form] results in decreased susceptibility to glimepiride
18 BIMP072198 Rattus norvegicus (Norway rat) Valproic acid results in increased methylation of ABCC8 gene
19 BIMP094277 Rattus norvegicus (Norway rat) Bisphenol A results in increased expression of ABCC8 mRNA
20 BIMP094277 Rattus norvegicus (Norway rat) Bisphenol A affects the expression of ABCC8 mRNA
21 BIMP094277 Rattus norvegicus (Norway rat) Bisphenol A results in decreased expression of ABCC8 mRNA
22 BIMP094277 Rattus norvegicus (Norway rat) Bisphenol A results in increased expression of ABCC8 mRNA
23 BIMP094277 Rattus norvegicus (Norway rat) Bisphenol A results in increased methylation of ABCC8 gene
24 BIMP095241 Rattus norvegicus (Norway rat) Ethanol results in increased expression of ABCC8 mrna|ethanol affects the expression of ABCC8 mRNA
25 BIMP094347 Rattus norvegicus (Norway rat) Mercaptopurine results in decreased expression of ABCC8 mRNA
26 BIMP094130 Rattus norvegicus (Norway rat) Triptonide results in increased expression of ABCC8 mRNA
27 BIMP091110 Rattus norvegicus (Norway rat) [estradiol 3-benzoate co-treated with [testosterone co-treated with estradiol]] results in increased expression of ABCC8 mRNA
28 BIMP091430 Rattus norvegicus (Norway rat) Dimethylnitrosamine results in decreased expression of ABCC8 mRNA
29 BIMP101071 Rattus norvegicus (Norway rat) Furan results in decreased expression of ABCC8 mRNA
30 BIMP101295 Rattus norvegicus (Norway rat) Diethylhexyl phthalate results in decreased expression of ABCC8 mRNA
31 BIMP101295 Rattus norvegicus (Norway rat) Diethylhexyl phthalate results in increased expression of ABCC8 mRNA
32 BIMP103258 Rattus norvegicus (Norway rat) Benzo(e)pyrene results in increased methylation of ABCC8 intron
33 BIMP101342 Rattus norvegicus (Norway rat) Ethyl-p-hydroxybenzoate results in decreased expression of ABCC8 mRNA
34 BIMP064420 Rattus norvegicus (Norway rat) Aflatoxin B1 results in increased methylation of ABCC8 exon
35 BIMP064424 Rattus norvegicus (Norway rat) ABCC8 protein inhibits the reaction [acetylcholine promotes the reaction [KCNJ8 protein results in increased transport of potassium]]
36 BIMP037097 Rattus norvegicus (Norway rat) Abrine results in decreased expression of ABCC8 mRNA
37 BIMP036503 Rattus norvegicus (Norway rat) Schizandrin B inhibits the reaction [carbon tetrachloride results in decreased expression of ABCC8 mrna]
38 BIMP026434 Rattus norvegicus (Norway rat) [1,2-dimethylhydrazine co-treated with folic acid] results in increased expression of ABCC8 mRNA
39 BIMP068094 Rattus norvegicus (Norway rat) Atrazine results in decreased expression of ABCC8 mRNA
40 BIMP068094 Rattus norvegicus (Norway rat) Atrazine affects the methylation of ABCC8 gene
41 BIMP090429 Rattus norvegicus (Norway rat) Dexamethasone inhibits the reaction [RX3 gene mutant form affects the expression of ABCC8 mrna]
42 BIMP090535 Rattus norvegicus (Norway rat) ABCC8 protein promotes the reaction [estradiol results in increased activity of CASP9 protein]|estradiol inhibits the reaction [glyburide binds to ABCC8 protein mutant form]|abcc8 protein promotes the reaction [estradiol results in increased activity of CASP8 protein]|abcc8 protein promotes the reaction [estradiol results in increased activity of CASP3 protein]|abcc8 protein results in increased susceptibility to estradiol|abcc8 protein mutant form results in increased susceptibility to estradiol|estradiol inhibits the reaction [glyburide binds to ABCC8 protein]|abcc8 protein mutant form results in decreased susceptibility to estradiol|adenosine triphosphate deficiency inhibits the reaction [estradiol inhibits the reaction [glyburide binds to ABCC8 protein]]|abcc8 protein affects the susceptibility to estradiol|estradiol binds to and affects the activity of ABCC8 protein|estradiol binds to ABCC8 protein mutant form
43 BIMP090535 Rattus norvegicus (Norway rat) [estradiol 3-benzoate co-treated with [testosterone co-treated with estradiol]] results in increased expression of ABCC8 mRNA
44 BIMP090994 Rattus norvegicus (Norway rat) Adenosine triphosphate deficiency inhibits the reaction [estradiol inhibits the reaction [glyburide binds to ABCC8 protein]]
45 BIMP090784 Rattus norvegicus (Norway rat) ABCC8 protein results in increased susceptibility to estrone
46 BIMP082212 Rattus norvegicus (Norway rat) Flavonoids results in increased expression of ABCC8 mRNA
47 BIMP082231 Rattus norvegicus (Norway rat) Genistein results in increased expression of ABCC8 mRNA
48 BIMP085926 Rattus norvegicus (Norway rat) Sulfadimethoxine results in decreased expression of ABCC8 mRNA
49 BIMP089333 Rattus norvegicus (Norway rat) Mifepristone results in decreased expression of ABCC8 mRNA
50 BIMP078712 Rattus norvegicus (Norway rat) Diethylstilbestrol results in decreased expression of ABCC8 mRNA