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Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
ABCC8
|
Homo sapiens (human)
|
Inhibitor
|
|
||
|
ABCC8
|
Rattus norvegicus (Norway rat)
|
Estradiol inhibits the reaction [glyburide binds to ABCC8 protein mutant form]|abcc8 protein results in increased susceptibility to glyburide|glyburide binds to ABCC8 protein|glyburide binds to ABCC8 protein mutant form|estradiol inhibits the reaction [glyburide binds to ABCC8 protein]|adenosine triphosphate deficiency inhibits the reaction [estradiol inhibits the reaction [glyburide binds to ABCC8 protein]]
|
https://ctdbase.org/detail.go?type=gene&acc=6833
|
||
|
ABCC8
|
Rattus norvegicus (Norway rat)
|
Resveratrol inhibits the reaction [glyburide binds to ABCC8 protein]
|
https://ctdbase.org/detail.go?type=gene&acc=6833
|
||
|
ABCC8
|
Homo sapiens (human)
|
Glyburide binds to and results in decreased activity of ABCC8 protein
|
https://ctdbase.org/detail.go?type=gene&acc=6833
|
||
|
ABCC8
|
Homo sapiens (human)
|
|
https://www.dgidb.org/genes/hgnc:59
|
||
|
ABCC8
|
Homo sapiens (human)
|
Blocker
|
https://www.dgidb.org/genes/hgnc:59
|
||
|
ABCC8
|
Homo sapiens (human)
|
Blocker
|
https://www.dgidb.org/genes/hgnc:59
|
||
|
ABCC8
|
Homo sapiens (human)
|
|
https://www.dgidb.org/genes/hgnc:59
|
||
|
ABCC8
|
Homo sapiens (human)
|
[KCNJ11 mutant form co-treated with ABCC8 mutant form] results in decreased susceptibility to glimepiride
|
https://ctdbase.org/detail.go?type=gene&acc=6833
|
||
|
ABCC8
|
Rattus norvegicus (Norway rat)
|
Gentamicins results in increased expression of ABCC8 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=6833
|
||
|
ABCC8
|
Homo sapiens (human)
|
Valproic acid results in increased methylation of ABCC8 gene
|
https://ctdbase.org/detail.go?type=gene&acc=6833
|
||
|
ABCC8
|
Homo sapiens (human)
|
[plant extracts co-treated with resveratrol] results in decreased expression of ABCC8 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=6833
|
||
|
ABCC8
|
Rattus norvegicus (Norway rat)
|
Resveratrol affects the activity of ABCC8 protein|abcc8 protein results in increased susceptibility to resveratrol
|
https://ctdbase.org/detail.go?type=gene&acc=6833
|
||
|
ABCC8
|
Rattus norvegicus (Norway rat)
|
Resveratrol inhibits the reaction [glyburide binds to ABCC8 protein]|resveratrol binds to ABCC8 protein
|
https://ctdbase.org/detail.go?type=gene&acc=6833
|
||
|
ABCC8
|
Rattus norvegicus (Norway rat)
|
Diethylstilbestrol results in decreased expression of ABCC8 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=6833
|
||
|
ABCC8
|
Rattus norvegicus (Norway rat)
|
Picrotoxin results in increased expression of ABCC8 mrna|picrotoxin results in decreased expression of ABCC8 mrna|picrotoxin results in increased expression of ABCC8 protein
|
https://ctdbase.org/detail.go?type=gene&acc=6833
|
||
|
ABCC8
|
Mus musculus (house mouse)
|
Bisphenol A results in increased expression of ABCC8 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=6833
|
||
|
ABCC8
|
Rattus norvegicus (Norway rat)
|
Bisphenol A affects the expression of ABCC8 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=6833
|
||
|
ABCC8
|
Rattus norvegicus (Norway rat)
|
Bisphenol A results in decreased expression of ABCC8 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=6833
|
||
|
ABCC8
|
Rattus norvegicus (Norway rat)
|
Bisphenol A results in increased expression of ABCC8 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=6833
|
||
|
ABCC8
|
Rattus norvegicus (Norway rat)
|
Bisphenol A results in increased methylation of ABCC8 gene
|
https://ctdbase.org/detail.go?type=gene&acc=6833
|
||
|
ABCC8
|
Mus musculus (house mouse)
|
Ethanol results in increased expression of ABCC8 mrna|ethanol affects the expression of ABCC8 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=6833
|
||
|
ABCC8
|
Rattus norvegicus (Norway rat)
|
Mercaptopurine results in decreased expression of ABCC8 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=6833
|
||
|
ABCC8
|
Mus musculus (house mouse)
|
Triptonide results in increased expression of ABCC8 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=6833
|
||
|
ABCC8
|
Rattus norvegicus (Norway rat)
|
Furan results in decreased expression of ABCC8 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=6833
|
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