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SCFBio, IIT Delhi Hauz Khas, New Delhi

Molecular Targets

Interactions between compounds and specific gene/protein targets.

Total Rows 750,454
Pages 30,019
BIMP_ID Target Name Gene Organism Action Source URL
ABCC8
Homo sapiens (human)
Inhibitor
ABCC8
Rattus norvegicus (Norway rat)
Estradiol inhibits the reaction [glyburide binds to ABCC8 protein mutant form]|abcc8 protein results in increased susceptibility to glyburide|glyburide binds to ABCC8 protein|glyburide binds to ABCC8 protein mutant form|estradiol inhibits the reaction [glyburide binds to ABCC8 protein]|adenosine triphosphate deficiency inhibits the reaction [estradiol inhibits the reaction [glyburide binds to ABCC8 protein]]
https://ctdbase.org/detail.go?type=gene&acc=6833
ABCC8
Rattus norvegicus (Norway rat)
Resveratrol inhibits the reaction [glyburide binds to ABCC8 protein]
https://ctdbase.org/detail.go?type=gene&acc=6833
ABCC8
Homo sapiens (human)
Glyburide binds to and results in decreased activity of ABCC8 protein
https://ctdbase.org/detail.go?type=gene&acc=6833
ABCC8
Homo sapiens (human)
https://www.dgidb.org/genes/hgnc:59
ABCC8
Homo sapiens (human)
Blocker
https://www.dgidb.org/genes/hgnc:59
ABCC8
Homo sapiens (human)
Blocker
https://www.dgidb.org/genes/hgnc:59
ABCC8
Homo sapiens (human)
https://www.dgidb.org/genes/hgnc:59
ABCC8
Homo sapiens (human)
[KCNJ11 mutant form co-treated with ABCC8 mutant form] results in decreased susceptibility to glimepiride
https://ctdbase.org/detail.go?type=gene&acc=6833
ABCC8
Rattus norvegicus (Norway rat)
Gentamicins results in increased expression of ABCC8 mRNA
https://ctdbase.org/detail.go?type=gene&acc=6833
ABCC8
Homo sapiens (human)
Valproic acid results in increased methylation of ABCC8 gene
https://ctdbase.org/detail.go?type=gene&acc=6833
ABCC8
Homo sapiens (human)
[plant extracts co-treated with resveratrol] results in decreased expression of ABCC8 mRNA
https://ctdbase.org/detail.go?type=gene&acc=6833
ABCC8
Rattus norvegicus (Norway rat)
Resveratrol affects the activity of ABCC8 protein|abcc8 protein results in increased susceptibility to resveratrol
https://ctdbase.org/detail.go?type=gene&acc=6833
ABCC8
Rattus norvegicus (Norway rat)
Resveratrol inhibits the reaction [glyburide binds to ABCC8 protein]|resveratrol binds to ABCC8 protein
https://ctdbase.org/detail.go?type=gene&acc=6833
ABCC8
Rattus norvegicus (Norway rat)
Diethylstilbestrol results in decreased expression of ABCC8 mRNA
https://ctdbase.org/detail.go?type=gene&acc=6833
ABCC8
Rattus norvegicus (Norway rat)
Picrotoxin results in increased expression of ABCC8 mrna|picrotoxin results in decreased expression of ABCC8 mrna|picrotoxin results in increased expression of ABCC8 protein
https://ctdbase.org/detail.go?type=gene&acc=6833
ABCC8
Mus musculus (house mouse)
Bisphenol A results in increased expression of ABCC8 mRNA
https://ctdbase.org/detail.go?type=gene&acc=6833
ABCC8
Rattus norvegicus (Norway rat)
Bisphenol A affects the expression of ABCC8 mRNA
https://ctdbase.org/detail.go?type=gene&acc=6833
ABCC8
Rattus norvegicus (Norway rat)
Bisphenol A results in decreased expression of ABCC8 mRNA
https://ctdbase.org/detail.go?type=gene&acc=6833
ABCC8
Rattus norvegicus (Norway rat)
Bisphenol A results in increased expression of ABCC8 mRNA
https://ctdbase.org/detail.go?type=gene&acc=6833
ABCC8
Rattus norvegicus (Norway rat)
Bisphenol A results in increased methylation of ABCC8 gene
https://ctdbase.org/detail.go?type=gene&acc=6833
ABCC8
Mus musculus (house mouse)
Ethanol results in increased expression of ABCC8 mrna|ethanol affects the expression of ABCC8 mRNA
https://ctdbase.org/detail.go?type=gene&acc=6833
ABCC8
Rattus norvegicus (Norway rat)
Mercaptopurine results in decreased expression of ABCC8 mRNA
https://ctdbase.org/detail.go?type=gene&acc=6833
ABCC8
Mus musculus (house mouse)
Triptonide results in increased expression of ABCC8 mRNA
https://ctdbase.org/detail.go?type=gene&acc=6833
ABCC8
Rattus norvegicus (Norway rat)
Furan results in decreased expression of ABCC8 mRNA
https://ctdbase.org/detail.go?type=gene&acc=6833
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