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Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
ABCC4
|
Mus musculus (house mouse)
|
NFE2L1 alternative form affects the reaction [arsenite results in increased expression of ABCC4 mrna]|arsenite results in increased expression of ABCC4 mrna|arsenite results in increased expression of ABCC4 protein|nfe2l1 alternative form affects the reaction [arsenite results in increased expression of ABCC4 protein]
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Danio rerio (zebrafish)
|
Cyclosporine affects the expression of ABCC4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Homo sapiens (human)
|
Cyclosporine affects the expression of ABCC4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Homo sapiens (human)
|
Cyclosporine results in increased expression of ABCC4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Mus musculus (house mouse)
|
Cyclosporine results in increased expression of ABCC4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Rattus norvegicus (Norway rat)
|
Cyclosporine results in increased expression of ABCC4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Mus musculus (house mouse)
|
Sulforaphane results in increased expression of ABCC4 protein|sulforaphane results in increased expression of ABCC4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Rattus norvegicus (Norway rat)
|
Sulfadimethoxine results in increased expression of ABCC4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Mus musculus (house mouse)
|
Fenretinide results in increased expression of ABCC4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Mus musculus (house mouse)
|
[andrographolide co-treated with beta-naphthoflavone] results in increased expression of ABCC4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Mus musculus (house mouse)
|
[piperonyl butoxide co-treated with diethylnitrosamine] results in increased expression of ABCC4 mrna|piperonyl butoxide results in increased expression of ABCC4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Homo sapiens (human)
|
Quercetin inhibits the reaction [alprostadil promotes the reaction [ABCC4 protein results in increased hydrolysis of adenosine triphosphate]]|abcc4 protein results in increased hydrolysis of adenosine triphosphate|hesperetin promotes the reaction [ABCC4 protein results in increased hydrolysis of adenosine triphosphate]|naringenin promotes the reaction [ABCC4 protein results in increased hydrolysis of adenosine triphosphate]|silymarin inhibits the reaction [ABCC4 protein results in increased hydrolysis of adenosine triphosphate]|silymarin inhibits the reaction [alprostadil promotes the reaction [ABCC4 protein results in increased hydrolysis of adenosine triphosphate]]|resveratrol promotes the reaction [ABCC4 protein results in increased hydrolysis of adenosine triphosphate]|quercetin affects the reaction [ABCC4 protein results in increased hydrolysis of adenosine triphosphate]|daidzein promotes the reaction [ABCC4 protein results in increased hydrolysis of adenosine triphosphate]
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Homo sapiens (human)
|
Adenosine triphosphate affects the activity of ABCC4 protein|[adenosine triphosphate affects the activity of ABCC4 protein] which results in increased transport of acetaminophen metabolite
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Homo sapiens (human)
|
ABCC4 protein binds to and results in increased hydrolysis of adenosine triphosphate|disulfiram inhibits the reaction [ABCC4 protein results in increased hydrolysis of adenosine triphosphate]
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Homo sapiens (human)
|
ABCC4 protein results in increased transport of penicillin G
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Homo sapiens (human)
|
Ethyl methanesulfonate results in decreased expression of ABCC4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Mus musculus (house mouse)
|
Testosterone deficiency results in increased expression of ABCC4 mrna|abcc1 gene mutant form inhibits the reaction [testosterone deficiency results in increased expression of ABCC4 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Homo sapiens (human)
|
|
https://www.dgidb.org/genes/hgnc:55
|
||
|
ABCC4
|
Homo sapiens (human)
|
ABCC4 protein affects the export of irinotecan
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Homo sapiens (human)
|
ABCC4 protein results in increased transport of cyclic AMP
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Mus musculus (house mouse)
|
ABCC4 protein affects the uptake of cyclic AMP analog|probenecid affects the reaction [ABCC4 protein affects the uptake of cyclic AMP analog]
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Danio rerio (zebrafish)
|
Ethinyl estradiol affects the expression of ABCC4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Mus musculus (house mouse)
|
Ethinyl estradiol results in increased expression of ABCC4 protein|metformin inhibits the reaction [ethinyl estradiol results in increased expression of ABCC4 protein]
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Rattus norvegicus (Norway rat)
|
Ethinyl estradiol results in increased expression of ABCC4 protein
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Homo sapiens (human)
|
[pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of ABCC4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
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