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Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
ABCC4
|
Mus musculus (house mouse)
|
Pirinixic acid results in increased expression of ABCC4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Rattus norvegicus (Norway rat)
|
Doxycycline results in decreased expression of ABCC4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Danio rerio (zebrafish)
|
Tetracycline affects the expression of ABCC4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Homo sapiens (human)
|
ABCC4 protein results in increased transport of tetracycline
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Rattus norvegicus (Norway rat)
|
Tetracycline results in increased expression of ABCC4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Danio rerio (zebrafish)
|
Thiram results in decreased expression of ABCC4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Homo sapiens (human)
|
[glycochenodeoxycholic acid co-treated with deoxycholic acid co-treated with chenodeoxycholic acid co-treated with glycodeoxycholic acid co-treated with glycocholic acid co-treated with triclosan] results in increased expression of ABCC4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Homo sapiens (human)
|
Triclosan results in increased expression of ABCC4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Mus musculus (house mouse)
|
[tectorigenin co-treated with 1-naphthylisothiocyanate] results in increased expression of ABCC4 protein
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Homo sapiens (human)
|
Daidzein inhibits the reaction [ABCC4 protein results in increased export of cyclic gmp]|daidzein promotes the reaction [ABCC4 protein results in increased hydrolysis of adenosine triphosphate]
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Rattus norvegicus (Norway rat)
|
Zearalenone results in decreased expression of ABCC4 protein|fulvestrant inhibits the reaction [zearalenone results in increased expression of ABCC4 mrna]|zearalenone results in increased expression of ABCC4 mrna|zearalenone results in increased expression of ABCC4 protein
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Mus musculus (house mouse)
|
Senecionine results in decreased expression of ABCC4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Homo sapiens (human)
|
Quercitrin results in decreased expression of ABCC4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Homo sapiens (human)
|
Silymarin inhibits the reaction [alprostadil promotes the reaction [ABCC4 protein results in increased hydrolysis of adenosine triphosphate]]|quercetin inhibits the reaction [alprostadil promotes the reaction [ABCC4 protein results in increased hydrolysis of adenosine triphosphate]]
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Homo sapiens (human)
|
Cholecalciferol results in decreased expression of ABCC4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Rattus norvegicus (Norway rat)
|
Calcitriol results in increased expression of ABCC4 protein|calcitriol results in increased activity of ABCC4 protein
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Mus musculus (house mouse)
|
Luteolin inhibits the reaction [cisplatin results in increased expression of ABCC4 protein]
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Homo sapiens (human)
|
Probenecid inhibits the reaction [ABCC4 protein results in increased transport of cyclic GMP]
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Mus musculus (house mouse)
|
Probenecid affects the reaction [ABCC4 protein affects the uptake of cyclic AMP analog]
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Rattus norvegicus (Norway rat)
|
[adefovir co-treated with probenecid] results in decreased expression of ABCC4 protein|[adefovir co-treated with probenecid co-treated with valsartan] affects the expression of ABCC4 protein|[adefovir co-treated with probenecid co-treated with cromolyn sodium] affects the expression of ABCC4 protein
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Mus musculus (house mouse)
|
[liquiritin co-treated with 1-naphthylisothiocyanate] results in increased expression of ABCC4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Homo sapiens (human)
|
Silymarin inhibits the reaction [alprostadil promotes the reaction [ABCC4 protein results in increased hydrolysis of adenosine triphosphate]]|silymarin inhibits the reaction [ABCC4 protein results in increased hydrolysis of adenosine triphosphate]|silymarin inhibits the reaction [ABCC4 protein results in increased export of cyclic GMP]
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Homo sapiens (human)
|
Hippuric acid inhibits the reaction [ABCC4 protein results in increased export of methotrexate]
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Homo sapiens (human)
|
Valproic acid inhibits the reaction [colforsin results in decreased expression of ABCC4 mrna]|colforsin results in decreased expression of ABCC4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Homo sapiens (human)
|
ABCC4 gene SNP affects the export of dinoprostone
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
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