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Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
ABCC4
|
Rattus norvegicus (Norway rat)
|
Doxorubicin affects the methylation of ABCC4 gene
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Homo sapiens (human)
|
Coumarin results in increased phosphorylation of ABCC4 protein
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Mus musculus (house mouse)
|
PPARA protein affects the reaction [clofibrate results in increased expression of ABCC4 mrna]|[clofibrate results in increased activity of PPARA protein] which results in increased expression of ABCC4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Mus musculus (house mouse)
|
Clofibrate results in increased expression of ABCC4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Mus musculus (house mouse)
|
PPARA promotes the reaction [clofibrate results in increased expression of ABCC4 protein]|clofibrate results in increased expression of ABCC4 protein|ppara promotes the reaction [clofibrate results in increased expression of ABCC4 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Rattus norvegicus (Norway rat)
|
[bisphenol A co-treated with diethylhexyl phthalate co-treated with dibutyl phthalate] affects the methylation of ABCC4 promoter
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Homo sapiens (human)
|
|
https://www.dgidb.org/genes/hgnc:55
|
||
|
ABCC4
|
Homo sapiens (human)
|
Ciprofloxacin results in increased expression of ABCC4 protein|gemfibrozil inhibits the reaction [[ciprofloxacin results in increased expression of ABCC4 protein] which results in decreased uptake of ciprofloxacin]|ciprofloxacin results in increased expression of ABCC4 mrna|[ciprofloxacin results in increased expression of ABCC4 protein] which results in decreased uptake of ciprofloxacin
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Mus musculus (house mouse)
|
ABCC4 protein results in increased export of ciprofloxacin
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Mus musculus (house mouse)
|
LEP gene mutant form affects the reaction [[methionine deficiency co-treated with choline deficiency] results in increased expression of ABCC4 mrna]|[methionine deficiency co-treated with choline deficiency] results in increased expression of ABCC4 protein|lepr gene mutant form affects the reaction [[methionine deficiency co-treated with choline deficiency] results in increased expression of ABCC4 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Mus musculus (house mouse)
|
[methionine co-treated with choline co-treated with folic acid co-treated with betaine co-treated with vitamin B 12 co-treated with zinc co-treated with phenobarbital] results in increased expression of ABCC4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Mus musculus (house mouse)
|
[methionine deficiency co-treated with choline deficiency co-treated with folic acid deficiency] results in increased expression of ABCC4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Mus musculus (house mouse)
|
[methionine deficiency co-treated with choline deficiency] results in increased expression of ABCC4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Mus musculus (house mouse)
|
RXRA affects the reaction [[methionine deficiency co-treated with choline deficiency] results in increased expression of ABCC4 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Rattus norvegicus (Norway rat)
|
[methionine deficiency co-treated with choline deficiency] results in increased expression of ABCC4 protein|[methionine deficiency co-treated with choline deficiency] results in increased expression of ABCC4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Homo sapiens (human)
|
Diclofenac affects the expression of ABCC4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Homo sapiens (human)
|
[estradiol co-treated with tetrachlorodibenzodioxin] results in increased expression of ABCC4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Rattus norvegicus (Norway rat)
|
Dexamethasone results in decreased expression of ABCC4 mrna|dexamethasone results in decreased expression of ABCC4 protein
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Homo sapiens (human)
|
[estradiol co-treated with progesterone] results in increased expression of ABCC4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Homo sapiens (human)
|
Estradiol results in increased expression of ABCC4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Rattus norvegicus (Norway rat)
|
[bisphenol A co-treated with estradiol] results in decreased expression of ABCC4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Homo sapiens (human)
|
ABCC4 protein results in increased transport of enalapril
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Homo sapiens (human)
|
[vincristine results in decreased susceptibility to vincristine] which results in decreased expression of ABCC4 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Homo sapiens (human)
|
Arsenite promotes the reaction [G3BP1 protein binds to ABCC4 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
||
|
ABCC4
|
Homo sapiens (human)
|
Sodium selenide inhibits the reaction [arsenite results in increased expression of ABCC4 protein]|sodium selenite inhibits the reaction [arsenite results in increased expression of ABCC4 protein]|arsenite results in increased expression of ABCC4 protein
|
https://ctdbase.org/detail.go?type=gene&acc=10257
|
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