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Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
ABCC3
|
Mus musculus (house mouse)
|
[caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with yohimbine co-treated with hydrolyzable tannins] results in increased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Mus musculus (house mouse)
|
8-epidiosbulbin E acetate results in decreased expression of ABCC3 protein
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Mus musculus (house mouse)
|
Menthol results in increased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Homo sapiens (human)
|
ABCC3 protein affects the reaction [chrysin results in increased transport of glutathione]
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Homo sapiens (human)
|
Glutathione promotes the reaction [ABCC3 protein affects the transport of calcein AM]
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Mus musculus (house mouse)
|
Uric acid promotes the reaction [1-naphthylisothiocyanate results in increased expression of ABCC3 mrna]|[1-naphthylisothiocyanate co-treated with uric acid] results in increased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Homo sapiens (human)
|
|
https://www.dgidb.org/genes/hgnc:54
|
||
|
ABCC3
|
Homo sapiens (human)
|
Allyl sulfide affects the expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Mus musculus (house mouse)
|
Allyl sulfide results in increased expression of ABCC3 mrna|[allyl sulfide results in increased activity of NR1I3 protein] which results in increased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Rattus norvegicus (Norway rat)
|
Allyl sulfide results in increased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Rattus norvegicus (Norway rat)
|
Allyl sulfide results in increased expression of ABCC3 protein|[allyl sulfide results in increased expression of ABCC3 protein] which affects the export of acetaminophen metabolite
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Homo sapiens (human)
|
Acetylcysteine inhibits the reaction [sulindac results in increased expression of ABCC3 protein]
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Homo sapiens (human)
|
[INS protein co-treated with dexamethasone co-treated with 1-methyl-3-isobutylxanthine co-treated with indomethacin co-treated with bisphenol F] results in decreased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Mus musculus (house mouse)
|
[caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with yohimbine co-treated with hydrolyzable tannins] results in increased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Mus musculus (house mouse)
|
Folic acid inhibits the reaction [1,2-dimethylhydrazine results in decreased expression of ABCC3 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Mus musculus (house mouse)
|
[methionine deficiency co-treated with choline deficiency co-treated with folic acid deficiency] results in decreased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Mus musculus (house mouse)
|
[vancomycin co-treated with imipenem] results in decreased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Mus musculus (house mouse)
|
[vancomycin co-treated with neomycin co-treated with ampicillin co-treated with metronidazole co-treated with amphotericin B] results in increased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Mus musculus (house mouse)
|
Glycyrrhizic acid affects the reaction [1-naphthylisothiocyanate affects the expression of ABCC3 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Homo sapiens (human)
|
[docetaxel results in decreased susceptibility to docetaxel] which results in increased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Homo sapiens (human)
|
ABCC3 affects the susceptibility to sorafenib
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Homo sapiens (human)
|
[[gasoline co-treated with 1-butanol] results in increased abundance of [particulate matter co-treated with polycyclic aromatic hydrocarbons]] which results in increased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Homo sapiens (human)
|
Aflatoxin B1 results in decreased methylation of ABCC3 exon
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Homo sapiens (human)
|
Aflatoxin B1 results in decreased methylation of ABCC3 gene
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Rattus norvegicus (Norway rat)
|
Aflatoxin B1 results in increased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
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