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Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
ABCC3
|
Homo sapiens (human)
|
Diallyl trisulfide results in decreased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Homo sapiens (human)
|
Diallyl trisulfide results in increased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Ovis aries (sheep)
|
[[biotin co-treated with pantothenic acid co-treated with INS protein co-treated with dexamethasone co-treated with 1-methyl-3-isobutylxanthine co-treated with rosiglitazone] results in increased susceptibility to bisphenol A] which results in decreased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Homo sapiens (human)
|
Diallyl disulfide affects the expression of ABCC3 mrna|diallyl disulfide results in increased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Mus musculus (house mouse)
|
[perfluorooctane sulfonic acid co-treated with cellulose] results in increased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Rattus norvegicus (Norway rat)
|
Acetamide results in increased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Homo sapiens (human)
|
[cyclosporine co-treated with glycochenodeoxycholic acid co-treated with deoxycholic acid co-treated with chenodeoxycholic acid co-treated with glycodeoxycholic acid co-treated with glycocholic acid] results in decreased expression of ABCC3 mrna|[nefazodone co-treated with glycochenodeoxycholic acid co-treated with deoxycholic acid co-treated with chenodeoxycholic acid co-treated with glycodeoxycholic acid co-treated with glycocholic acid] results in decreased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Homo sapiens (human)
|
Deoxycholic acid results in increased activity of ABCC3 protein
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Homo sapiens (human)
|
Deoxycholic acid results in increased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Homo sapiens (human)
|
[glycochenodeoxycholic acid co-treated with deoxycholic acid co-treated with chenodeoxycholic acid co-treated with glycodeoxycholic acid co-treated with glycocholic acid co-treated with 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt] results in decreased expression of ABCC3 mrna|[glycochenodeoxycholic acid co-treated with deoxycholic acid co-treated with chenodeoxycholic acid co-treated with glycodeoxycholic acid co-treated with glycocholic acid co-treated with tartrazine] results in decreased expression of ABCC3 mrna|[glycochenodeoxycholic acid co-treated with deoxycholic acid co-treated with chenodeoxycholic acid co-treated with glycodeoxycholic acid co-treated with glycocholic acid co-treated with acetaminophen] results in decreased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Mus musculus (house mouse)
|
Deoxycholic acid affects the expression of ABCC3 mrna|slco1a1 protein affects the susceptibility to [deoxycholic acid affects the expression of ABCC3 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Mus musculus (house mouse)
|
Deoxycholic acid results in decreased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Homo sapiens (human)
|
Aristolochic acid I results in increased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Rattus norvegicus (Norway rat)
|
[aristolochic acid I co-treated with aristolochic acid II] results in increased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Rattus norvegicus (Norway rat)
|
Aristolochic acid I results in increased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Homo sapiens (human)
|
Cholates results in increased activity of ABCC3 protein
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Homo sapiens (human)
|
Cholic acid results in increased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Mus musculus (house mouse)
|
Cholic acid results in increased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Homo sapiens (human)
|
Valproic acid affects the expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Homo sapiens (human)
|
Valproic acid results in decreased expression of ABCC3 mrna|valproic acid results in increased expression of ABCC3 protein|valproic acid results in decreased methylation of ABCC3 gene
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Homo sapiens (human)
|
Valproic acid results in increased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Rattus norvegicus (Norway rat)
|
Valproic acid results in decreased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Rattus norvegicus (Norway rat)
|
Valproic acid results in increased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Homo sapiens (human)
|
Resveratrol metabolite promotes the reaction [ABCC3 protein results in increased transport of estradiol-17 beta-glucuronide]
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Homo sapiens (human)
|
Resveratrol results in increased expression of ABCC3 protein|resveratrol results in increased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
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