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Interactions between compounds and specific gene/protein targets.
| BIMP_ID | Target Name | Gene | Organism | Action | Source URL |
|---|---|---|---|---|---|
|
ABCC3
|
Mus musculus (house mouse)
|
Dibenzofurans results in increased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Rattus norvegicus (Norway rat)
|
Doxycycline results in decreased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Rattus norvegicus (Norway rat)
|
Tetracycline results in increased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Homo sapiens (human)
|
Mifepristone results in increased expression of ABCC3 mrna|[mifepristone results in increased activity of NR1I2 protein] which results in increased expression of ABCC3 mrna|mifepristone results in increased activity of ABCC3 protein
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Mus musculus (house mouse)
|
Mifepristone results in increased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Homo sapiens (human)
|
Dexamethasone results in increased expression of ABCC3 protein|dexamethasone results in increased activity of ABCC3 protein|dexamethasone promotes the reaction [ABCC3 protein affects the transport of calcein AM]
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Homo sapiens (human)
|
Dexamethasone results in increased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Homo sapiens (human)
|
[INS protein co-treated with dexamethasone co-treated with 1-methyl-3-isobutylxanthine co-treated with indomethacin co-treated with bisphenol A] results in decreased expression of ABCC3 mrna|[ins protein co-treated with dexamethasone co-treated with 1-methyl-3-isobutylxanthine co-treated with indomethacin co-treated with bisphenol S] results in decreased expression of ABCC3 mrna|[ins protein co-treated with dexamethasone co-treated with 1-methyl-3-isobutylxanthine co-treated with indomethacin co-treated with bisphenol F] results in decreased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Ovis aries (sheep)
|
[[biotin co-treated with pantothenic acid co-treated with INS protein co-treated with dexamethasone co-treated with 1-methyl-3-isobutylxanthine co-treated with rosiglitazone] results in increased susceptibility to bisphenol A] which results in decreased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Rattus norvegicus (Norway rat)
|
Dexamethasone affects the expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Rattus norvegicus (Norway rat)
|
Dexamethasone inhibits the reaction [lipopolysaccharides results in increased expression of ABCC3 mrna]
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Rattus norvegicus (Norway rat)
|
Dexamethasone results in decreased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Rattus norvegicus (Norway rat)
|
Dexamethasone results in decreased expression of ABCC3 protein
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Rattus norvegicus (Norway rat)
|
Dexamethasone results in increased expression of ABCC3 protein
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Homo sapiens (human)
|
ABCC3 protein results in increased uptake of estradiol
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Homo sapiens (human)
|
[cycloheximide co-treated with estradiol] results in increased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Homo sapiens (human)
|
[estradiol co-treated with tetrachlorodibenzodioxin] results in increased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Homo sapiens (human)
|
Estradiol results in decreased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Homo sapiens (human)
|
Estradiol results in increased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Homo sapiens (human)
|
[progesterone co-treated with estradiol] results in decreased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Rattus norvegicus (Norway rat)
|
Estradiol results in decreased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Homo sapiens (human)
|
Hydrocortisone results in increased expression of ABCC3 mrna|hydrocortisone results in increased activity of ABCC3 protein|hydrocortisone promotes the reaction [ABCC3 protein affects the transport of calcein AM]
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Homo sapiens (human)
|
|
https://www.dgidb.org/genes/hgnc:54
|
||
|
ABCC3
|
Mus musculus (house mouse)
|
[acetaminophen co-treated with propylene glycol] results in increased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
||
|
ABCC3
|
Homo sapiens (human)
|
Dihydrotestosterone results in increased expression of ABCC3 mRNA
|
https://ctdbase.org/detail.go?type=gene&acc=8714
|
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